dc.contributor.advisorIsaza-Restrepo, Daniel 
dc.contributor.advisorDennis Verano, Rodolfo José 
dc.creatorIdrovo Turbay, Álvaro Enrique 
dc.creatorCortes-Puentes, Luis Arcadio 
dc.creatorAldana, Víctor 
dc.creatorVasquez, Sergio 
dc.creatorIsaza, Daniel 
dc.creatorDennis, Rodolfo 
dc.date.accessioned2017-02-22T16:14:32Z
dc.date.available2017-02-22T16:14:32Z
dc.date.created2017-02
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/13063
dc.descriptionObjetivo: Evaluar la eficacia diagnóstica de CardioDetect (Proteína ligadora de ácidos grasos del miocito) contra la troponina I en la detección temprana del Infarto Agudo de Miocardio, en un grupo de pacientes con dolor torácico típico agudo en el servicio urgencias de la Fundación Cardioinfantil – Instituto de Cardiología. Métodos: Estudio de prueba diagnóstica, de corte transversal en el servicio de urgencias de la Fundación Cardioinfantil – Instituto de Cardiología. Se evaluó el rendimiendo diagnóstico de la proteína ligadora de ácidos grasos del miocito en 38 pacientes (28 pacientes con diagnóstico de infarto agudo de miocardio y 10 pacientes con diagnóstico de angina inestable) quienes consultaron al servicio de urgencias de la Fundación Cardioinfantil dentro de las 3 pimeras horas de inicio de los síntomas. Resultados: El promedio de edad fue de 63 años. De los 28 pacientes con síndrome coronario tipo infarto agudo de miocardio, Cardiodetect® resultó positiva en 27 ocasiones, mientras que resultó positiva en 1 de 10 pacientes con diagnóstico final de angina inestable, calculándose sensibilidad y valor predictivo positivo de 96.4%, especificidad y valor predictivo negativo de 90%, LR positivo 9.64 y LR negativo 0.04. En cuanto a la troponina, de los 28 pacientes con infarto agudo de miocardio, mostró positividad en 15 casos mientras en los pacientes con diagnóstico final de angina inestable no hubo positividad en ningún paciente, calculándose entonces sensibilidad del 53%, especificidad de 100%, VPP 100% y valor predictivo negativo 43.5%.
dc.description.abstractObjective To evaluate the diagnostic efficacy of CardioDetect (Heart type fatty acid binding protein) against Troponin I in the early detection of myocardial infarction in patients with acute chest pain in the emergency department of the Cardioinfantil Foundation – Cardiology Institute . Materials and methods: Diagnostic test study, cross-sectional in the emergency department of the Cardioinfantil Foundation - Cardiology Institute. The diagnostic performance of the myocyte fatty acid binding protein was evaluated in 38 patients (28 patients with a diagnosis of acute myocardial infarction and 10 patients with a diagnosis of unstable angina) who consulted the emergency department of the Cardioinfantil Foundation within 3 first hours of onset of symptoms. Results: The average age was 63 years. Of the 28 patients with acute myocardial infarction coronary syndrome, Cardiodetect® was positive in 27 occasions, while it was positive in 1 of 10 patients with a final diagnosis of unstable angina, with a sensitivity and a positive predictive value of 96.4%, specificity and value Predictive negative of 90%, likelihood ratio positive 9.64 and likelihood ratio negative 0.04. As for troponin, of the 28 patients with acute myocardial infarction, it showed positivity in 15 cases, whereas in patients with a final diagnosis of unstable angina, there was no positivity in any patient, with a sensitivity of 53%, specificity of 100% Positive predictive value of 100%, negative predictive value of 43.5%.
dc.description.sponsorshiplaboratorio Biopass
dc.format.mimetypeapplication/pdf
dc.language.isospa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.sourceinstname:Universidad del Rosario
dc.sourcereponame:Repositorio Institucional EdocUR
dc.subjectProteína ligadora de ácidos grasos del miocito
dc.subjectTroponina
dc.subjectSindrome coronario agudo
dc.subject.ddc616.1237
dc.titleRendimiento de la proteína ligadora de ácidos grasos del miocito para el diagnóstico de infarto de miocardio
dc.typebachelorThesis
dc.publisherUniversidad del Rosario
dc.creator.degreeEspecialista en Cardiología
dc.publisher.programEspecialización en Cardiología
dc.publisher.departmentFacultad de Medicina
dc.subject.keywordMyocyte fatty acid binding protein
dc.subject.keywordTroponin
dc.subject.keywordAcute coronary syndrome
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.subject.decsCardiomiopatías
dc.subject.decsProteína de Unión a Andrógenos -- Funcionamiento
dc.subject.decsInfarto -- Investigaciones
dc.type.spaTrabajo de grado
dc.rights.accesoAbierto (Texto completo)
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
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dc.rights.ccAtribución-NoComercial-SinDerivadas 2.5 Colombia
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