dc.creatorNiño-Ruiz, Carmen 
dc.creatorMorón-Duarte, Lina 
dc.creatorÁlvarez-Larrañaga, Martha I. 
dc.date.accessioned2019-02-08T17:40:31Z
dc.date.available2019-02-08T17:40:31Z
dc.date.created2015
dc.identifier.issnISSN 0123-9392
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/19027
dc.descriptionIntroduction In recent years, there has been an increase in the number of cases of pertussis, predominantly affecting infants under one year of age, teenagers and adults. In 2005, the Advisory Committee on Immunization Practices of the United States (ACIP) recommended administering a booster shot of acellular pertussis-containing vaccine for teenagers, a strategy adopted by various countries. Our objective was to perform a systematic review of the short-term effectiveness of this preventive strategy. As far as we know, this review has not been performed to date. Methods A systematic literature review of publications in English and Spanish on the short-term effectiveness of a reduced antigen content diphteria-tetanus-acellular pertussis vaccine (Tdap) as a booster shot for teenagers, between January 1990 and December 2012. Results An initial search revealed a total of 121 results; of 26 papers preselected, 4 were included in the review. They were classified as level of evidence Ib. The immunogenicity against tetanus and diphtheria was tested with the Tdap vaccine versus tetanus, reduced diphtheria (Td). The authors found that the immune responses were significant and similar. The responses to the Tdap against specific antigens of Bordetella pertussis, diphtheria and tetanus were appropriate and significant. The reactogenicity was low, and the most common local adverse event was pain, predominantly in the group that received Tdap. Conclusions Available evidence supports the strategy of using Tdap vaccine as a booster in teenagers from 10 to 18 years of age. This conclusion is based on its low reactogenicity and its adequate immunogenicity against tetanus, diphtheria and Bordetella pertussis. © 2014 ACIN. Published by Elsevier España, S.L.U. This is an open access article under the CCBY-NC-ND license.
dc.format.mimetypeapplication/pdf
dc.language.isospa
dc.relation.ispartofInfectio, ISSN: 0123-9392, Vol. 19/No. 3 (2015) pp. 115-123
dc.relation.urihttps://www.clinicalkey.es/service/content/pdf/watermarked/1-s2.0-S0123939215000260.pdf?locale=es_ES
dc.rights.uri
dc.subjectAdolescents
dc.subjectMetanalysis
dc.subjectTetanus Diphtheriaa Celular Pertussis Containing Vaccine
dc.subjectVaccines
dc.subject.ddc616
dc.subject.lembTos ferina
dc.subject.lembVacunas
dc.subject.lembTetanos
dc.subject.lembDifteria
dc.titleEfectividad a corto plazo de la vacuna antipertusis en adolescentes : revisión sistemática
dc.typearticle
dc.title.alternativeShort term effectiveness of acellular pertussis vaccine in teenagers : a systematic review
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.subject.decsDiphtheria Pertussis Tetanus Vaccine
dc.subject.decsPertussis Vaccine
dc.subject.decsAdolescent
dc.subject.decsAntigen Specificity
dc.subject.decsArticle
dc.subject.decsBordetella Pertussis
dc.subject.decsDrug Efficacy
dc.subject.decsHuman
dc.subject.decsImmune Response
dc.subject.decsImmunogenicity
dc.subject.decsSystematic Review
dc.subject.decsBordetella Pertussis
dc.type.spaArtículo
dc.rights.accesoAbierto (Texto Completo)
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.rights.cc https://creativecommons.org/licenses/by-nc-nd/4.0/  
dc.creator.googleNiño-Ruiz, Carmen
dc.creator.googleMorón-Duarte, Lina
dc.creator.googleÁlvarez-Larrañaga, Martha I.


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