dc.creatorGalindo-Mendez, Brahyan 
dc.creatorMayor, Luis C. 
dc.creatorVelandia-Hurtado, Fernando 
dc.creatorCalderon-Ospina, Carlos-Alberto 
dc.date.accessioned2019-02-08T21:09:10Z
dc.date.available2019-02-08T21:09:10Z
dc.date.created2015
dc.identifier.issnISSN 2213-3232
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/19032
dc.descriptionMedically intractable epilepsy is a clinical condition of concern that arises when a patient with epilepsy suffers seizures, despite a trial of two or more antiepileptic drugs (AEDs) suitable for the type of epilepsy that are prescribed at maximum tolerated doses, does not achieve control of seizures. This diagnosis could be related to cortical dysplasias. We report the case of a 5-year-old girl with a previous normal neurological development and no family history of epilepsy who presented with focal-type seizures at age 4. She started treatment by taking different AEDs for seizure control. She continued having frequent seizures that sometimes progressed to generalized seizures and status epilepticus. After a focal cortical resection performed in the area where interictal spikes were detected, the pathology confirmed a type IIb cortical dysplasia as the cause of the epilepsy. This article discusses cortical dysplasias as a cause of pharmacoresistant epilepsy and its treatment. © 2015 The Authors.
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.relation.ispartofEpilepsy and Behavior Case Reports, ISSN: 2213-3232, Vol. 4 (2015) pp. 6-8
dc.relation.urihttps://ac.els-cdn.com/S2213323215000122/1-s2.0-S2213323215000122-main.pdf?_tid=49d8aeaf-6824-4c12-9de0-f79b4ba884c5&acdnat=1540056559_255e913a891300b3ccc0f5611b6541f6
dc.rights.uri
dc.subjectAnticonvulsants
dc.subjectCortical Dysplasia-Focal Epilepsy Syndrome
dc.subjectDrug Resistance
dc.subjectEpilepsy
dc.subjectMalformations Of Cortical Development
dc.subject.ddc616.853
dc.subject.lembEpilepsia
dc.subject.lembConvulsiones
dc.subject.lembNiños epilépticos
dc.titleFailure of antiepileptic drugs in controlling seizures in epilepsy : What do we do next?
dc.typearticle
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.subject.decsAnticonvulsive Agent
dc.subject.decsCarbamazepine
dc.subject.decsClonazepam
dc.subject.decsEtiracetam
dc.subject.decsGabapentin
dc.subject.decsHarkoseride
dc.subject.decsLamotrigine
dc.subject.decsMidazolam
dc.subject.decsOxcarbazepine
dc.subject.decsPhenobarbital
dc.subject.decsPrimidone
dc.subject.decsTopiramate
dc.subject.decsArticle
dc.subject.decsAtaxia
dc.subject.decsBrain Cortex Lesion
dc.subject.decsBrain Surgery
dc.subject.decsCase Report
dc.subject.decsChild
dc.subject.decsCortical Dysplasia
dc.subject.decsDisease Control
dc.subject.decsDisease Course
dc.subject.decsDrug Eruption
dc.subject.decsDrug Treatment Failure
dc.subject.decsEpileptic State
dc.subject.decsFamily History
dc.subject.decsFemale
dc.subject.decsFocal Epilepsy
dc.subject.decsHuman
dc.subject.decsIntractable Epilepsy
dc.subject.decsNervous System Development
dc.subject.decsOnset Age
dc.subject.decsPreschool Child
dc.subject.decsPriority Journal
dc.subject.decsSeizure
dc.subject.decsTonic Clonic Seizure
dc.type.spaArtículo
dc.rights.accesoAbierto (Texto Completo)
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.source.bibliographicCitationWirrel, E.C., Predicting pharmacoresistance in pediatric epilepsy (2013) Epilepsia, 54, pp. 19-22
dc.rights.cchttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.creator.googleGalindo-Mendez, Brahyan
dc.creator.googleMayor, Luis C.
dc.creator.googleVelandia-Hurtado, Fernando
dc.creator.googleCalderon-Ospina, Carlos


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