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Failure of antiepileptic drugs in controlling seizures in epilepsy : What do we do next?

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dc.creatorGalindo-Mendez, Brahyan
dc.creatorMayor, Luis C.
dc.creatorVelandia Hurtado, Fernando Alfredo
dc.creatorCalderón Ospina, Carlos Alberto
dc.creator.googleGalindo-Mendez, Brahyan
dc.creator.googleMayor, Luis C.
dc.creator.googleVelandia-Hurtado, Fernando
dc.creator.googleCalderon-Ospina, Carlos
dc.date.accessioned2019-02-08T21:09:10Z
dc.date.available2019-02-08T21:09:10Z
dc.date.created2015
dc.date.issued2015
dc.description.abstractMedically intractable epilepsy is a clinical condition of concern that arises when a patient with epilepsy suffers seizures, despite a trial of two or more antiepileptic drugs (AEDs) suitable for the type of epilepsy that are prescribed at maximum tolerated doses, does not achieve control of seizures. This diagnosis could be related to cortical dysplasias. We report the case of a 5-year-old girl with a previous normal neurological development and no family history of epilepsy who presented with focal-type seizures at age 4. She started treatment by taking different AEDs for seizure control. She continued having frequent seizures that sometimes progressed to generalized seizures and status epilepticus. After a focal cortical resection performed in the area where interictal spikes were detected, the pathology confirmed a type IIb cortical dysplasia as the cause of the epilepsy. This article discusses cortical dysplasias as a cause of pharmacoresistant epilepsy and its treatment. © 2015 The Authors.eng
dc.format.mimetypeapplication/pdf
dc.identifier.issnISSN 2213-3232
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/19032
dc.language.isoengspa
dc.relation.citationEndPage8
dc.relation.citationStartPage6
dc.relation.citationTitleEpilepsy and Behavior Case Reports
dc.relation.citationVolumeVol. 4
dc.relation.ispartofEpilepsy and Behavior Case Reports, ISSN: 2213-3232, Vol. 4 (2015) pp. 6-8spa
dc.relation.urihttps://ac.els-cdn.com/S2213323215000122/1-s2.0-S2213323215000122-main.pdf?_tid=49d8aeaf-6824-4c12-9de0-f79b4ba884c5&acdnat=1540056559_255e913a891300b3ccc0f5611b6541f6spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.rights.cchttps://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.source.bibliographicCitationWirrel, E.C., Predicting pharmacoresistance in pediatric epilepsy (2013) Epilepsia, 54, pp. 19-22spa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subjectAnticonvulsantsspa
dc.subjectCortical Dysplasia-Focal Epilepsy Syndromespa
dc.subjectDrug Resistancespa
dc.subjectEpilepsyspa
dc.subjectMalformations Of Cortical Developmentspa
dc.subject.ddcEnfermedadesspa
dc.subject.decsAnticonvulsive Agentspa
dc.subject.decsCarbamazepinespa
dc.subject.decsClonazepamspa
dc.subject.decsEtiracetamspa
dc.subject.decsGabapentinspa
dc.subject.decsHarkoseridespa
dc.subject.decsLamotriginespa
dc.subject.decsMidazolamspa
dc.subject.decsOxcarbazepinespa
dc.subject.decsPhenobarbitalspa
dc.subject.decsPrimidonespa
dc.subject.decsTopiramatespa
dc.subject.decsArticlespa
dc.subject.decsAtaxiaspa
dc.subject.decsBrain Cortex Lesionspa
dc.subject.decsBrain Surgeryspa
dc.subject.decsCase Reportspa
dc.subject.decsChildspa
dc.subject.decsCortical Dysplasiaspa
dc.subject.decsDisease Controlspa
dc.subject.decsDisease Coursespa
dc.subject.decsDrug Eruptionspa
dc.subject.decsDrug Treatment Failurespa
dc.subject.decsEpileptic Statespa
dc.subject.decsFamily Historyspa
dc.subject.decsFemalespa
dc.subject.decsFocal Epilepsyspa
dc.subject.decsHumanspa
dc.subject.decsIntractable Epilepsyspa
dc.subject.decsNervous System Developmentspa
dc.subject.decsOnset Agespa
dc.subject.decsPreschool Childspa
dc.subject.decsPriority Journalspa
dc.subject.decsSeizurespa
dc.subject.decsTonic Clonic Seizurespa
dc.subject.lembEpilepsiaspa
dc.subject.lembConvulsionesspa
dc.subject.lembNiños epilépticosspa
dc.titleFailure of antiepileptic drugs in controlling seizures in epilepsy : What do we do next?spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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