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Genomic architecture of adaptive color pattern divergence and convergence in Heliconius butterflies

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dc.audienceComunidad Rosaristaspa
dc.creatorSupple, Megan A.
dc.creatorHines, Heather M.
dc.creatorDasmahapatra, Kanchon K.
dc.creatorLewis, James J.
dc.creatorNielsen, Dahlia M.
dc.creatorLavoie, Christine
dc.creatorRay, David A.
dc.creatorSalazar, Camilo
dc.creatorOwen McMillan, W.
dc.creatorCounterman, Brian
dc.creator.googleSupple, Megan A.
dc.creator.googleHines, Heather M.
dc.creator.googleDasmahapatra, Kanchoon K.
dc.creator.googleLewis, James J.
dc.creator.googleNielsen, Dahlia M.
dc.creator.googleLavoie, Christine
dc.creator.googleRay, David A.
dc.creator.googleSalazar, Camilo
dc.creator.googleOwen McMillan, W.
dc.creator.googleCounterman, Brian A.
dc.date.accessioned2014-08-13T15:35:45Z
dc.date.available2014-08-13T15:35:45Z
dc.date.created2013
dc.date.issued2013
dc.description.abstractIdentifying the genetic changes driving adaptive variation in natural populations is key to understanding the origins of biodiversity. The mosaic of mimetic wing patterns in Heliconius butterflies makes an excellent system for exploring adaptive variation using next-generation sequencing. In this study, we use a combination of techniques to annotate the genomic interval modulating red color pattern variation, identify a narrow region responsible for adaptive divergence and convergence in Heliconius wing color patterns, and explore the evolutionary history of these adaptive alleles. We use whole genome resequencing from four hybrid zones between divergent color pattern races of Heliconius erato and two hybrid zones of the co-mimic Heliconius melpomene to examine genetic variation across 2.2 Mb of a partial reference sequence. In the intergenic region near optix, the gene previously shown to be responsible for the complex red pattern variation in Heliconius, population genetic analyses identify a shared 65-kb region of divergence that includes several sites perfectly associated with phenotype within each species. This region likely contains multiple cis-regulatory elements that control discrete expression domains of optix. The parallel signatures of genetic differentiation in H. erato and H. melpomene support a shared genetic architecture between the two distantly related co-mimics; however, phylogenetic analysis suggests mimetic patterns in each species evolved independently. Using a combination of next-generation sequencing analyses, we have refined our understanding of the genetic architecture of wing pattern variation in Heliconius and gained important insights into the evolution of novel adaptive phenotypes in natural populations.eng
dc.format.mediumRecurso electrónicospa
dc.format.mimetypeapplication/pdf
dc.format.tipoDocumentospa
dc.identifier.doihttps://doi.org/10.1101/gr.150615.112
dc.identifier.issnISSN:10889051
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/8824
dc.language.isoeng
dc.publisherUniversidad del Rosariospa
dc.relation.citationIssueNo. 8
dc.relation.citationTitleGenome Research
dc.relation.citationVolumeVol. 23
dc.relation.ispartofGenome Research ISSN 10889051 V. 23 N. 8 2013spa
dc.relation.urihttp://genome.cshlp.org/content/23/8/1248.full.pdf+html
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto completo)spa
dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma.spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.ddcEvolución & genética
dc.subject.decsGenomaspa
dc.subject.decsGenesspa
dc.subject.decsMariposasspa
dc.subject.decsGenéticaspa
dc.titleGenomic architecture of adaptive color pattern divergence and convergence in Heliconius butterfliesspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaArtículospa
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