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Alteraciones respiratorias durante el sueño en niños con Síndrome Down a la altura de Bogotá

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dc.contributor.advisorDueñas, Elida
dc.contributor.advisorMorón Duarte, Lina Sofía
dc.creatorPinzón Gómez, Ginna Cecilia
dc.creator.degreeEspecialista en Pediatría
dc.date.accessioned2013-07-12T13:17:00Z
dc.date.available2013-07-12T13:17:00Z
dc.date.created2013-06-11
dc.date.issued2013
dc.descriptionObjetivo: determinar la frecuencia de las diferentes alteraciones respiratorias durante el sueño (ARS) e hipertensión pulmonar (HTP) y establecer la saturación de oxígeno (SpO2) en vigilia, sueño y durante los eventos en niños con Síndrome Down (SD) a la altura de Bogotá (2640m) de acuerdo a grupos de edad e IMC. Métodos: estudio descriptivo de corte transversal, se incluyeron todos los niños con SD con sospecha de ARS remitidos a polisonograma (PSG) de octubre de 2011 a enero de 2013 a la Fundación Neumológica Colombina (FNC). Se dividieron en 3 grupos: apnea obstructiva, apnea obstructiva y central, sin apneas. Resultados: 74 niños, el 36,5% mujeres, edad media 4 años. 47,3% presento apnea obstructiva, más frecuente en >2 años, 35,1% apnea obstructiva y central, más frecuente en < 2 años y 17,6 % sin apnea. SpO2 promedio en apnea obstructiva 84,63%, apnea obstructiva y central: 81,8% y sin apnea: 86,85% (p 0,058). 23% presento obesidad, 16% con apnea obstructiva. 53 pacientes tenían ecocardiograma: 28% HTP, 53,3% tuvo apnea obstructiva y 26,7 apnea obstructiva y central, no diferencias significativas. SpO2 promedio en HTP 88,3% vigilia, 86,2% sueño REM, 85,7 % sueño no REM, no diferencia significativa comparada con pacientes sin HTP. Conclusiones: Las ARS son frecuentes en los niños con SD, La desaturación está presente en los niños con SD independiente del tipo de apnea. A todos los niños SD se les debe practicar un PSG en el primer año de vida.spa
dc.description.abstractObjective: To determine the frequency of sleep apnea syndromes (SAS) and pulmonary hypertension (PHT) and set the oxygen saturation (SpO2) during wakefulness, sleep and events in children with Down syndrome (DS) living in Bogota (2640m) according to age groups and BMI. Methods: Descriptive cross sectional study, we included all children with DS referred to Fundación Neumológica Colombiana to make a polysomnogram (PSG) between October 2011 and January 2013. They were divided into 3 groups: obstructive sleep apnea, central and obstructive apnea, without apnea. Results: 74 children, 36. 5% women, mean age 4 years. 47. 3% showed obstructive apnea, more common in &gt; 2 years, 35. 1% central and obstructive apnea more common in &lt; 2 years, and 17. 6% without apnea. Average SpO2 in obstructive apnea 84. 63%, central and obstructive apnea: 81. 8% without apnea: 86. 85% (p 0. 058). 23% showed obesity, 16% with obstructive apnea. 53 patients had echocardiography: PHT 28%, 53. 3% obstructive apnea and 26. 7% central and obstructive apnea, no significant differences. Average SpO2 in PHT 88. 3% wake, 86. 2% REM sleep, 85. 7% non-REM sleep, no significant difference compared with patients without PHT. Conclusions: SAS are common in children with DS; desaturation is present in children with DS independent of the kind of sleep apnea. All DS children should have a PSG in the first year of life. eng
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dc.identifier.doihttps://doi.org/10.48713/10336_4461
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/4461
dc.language.isospa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentFacultad de medicinaspa
dc.publisher.programEspecialización en Pediatríaspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto completo)spa
dc.rights.ccAtribución-NoComercial-SinDerivadas 2.5 Colombiaspa
dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARÁGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe.spa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
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dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectSíndromes de la Apnea del Sueñospa
dc.subjectSíndrome de Downspa
dc.subjectHipertensión Pulmonarspa
dc.subject.decsHIPERTENSIÓN PULMONARspa
dc.subject.decsSÍNDROME DE DOWNspa
dc.subject.decsSÍNDROMES DE LA APNEA DEL SUEÑO - ETIOLOGÍAspa
dc.subject.keywordSleep Apnea Syndromeseng
dc.subject.keywordDown Syndromeeng
dc.subject.keywordPulmonary Hypertensioneng
dc.titleAlteraciones respiratorias durante el sueño en niños con Síndrome Down a la altura de Bogotáspa
dc.typemasterThesiseng
dc.type.hasVersioninfo:eu-repo/semantics/submittedVersion
dc.type.spaTrabajo de gradospa
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