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Caracterización de pacientes pediátricos con cetoacidosis diabética de acuerdo a la presentación de la diabetes mellitus en hospitales de Colombia, 2017 – 2018

dc.contributorVásquez Hoyos, Pablo
dc.contributor.advisorPardo, Rosalba
dc.creatorLara Bernal, Marleny Aurora
dc.creator.degreeEspecialista en Cuidado Intensivo Pediátricospa
dc.creator.degreetypeFull timespa
dc.date.accessioned2019-02-11T16:41:00Z
dc.date.available2019-02-11T16:41:00Z
dc.date.created2019-01-31
dc.date.issued2019
dc.descriptionLa cetoacidosis diabética (CAD) en pediatría es una complicación frecuente de la diabetes mellitus tipo 1 (DM-1). Diversos factores influyen en la respuesta al tratamiento y su comportamiento metabólico puede tener variaciones de acuerdo a si el diabético es conocido o es un debut. Objetivo: Se describen las variables asociadas a la CAD en pacientes menores de 18 años, incluyendo características demográficas, clínicas, paraclínicas, estancia hospitalaria y complicaciones. Materiales y método: Estudio de corte transversal, de una muestra de 391 pacientes pediátricos estratificados por severidad de la CAD al ingreso entre julio de 2007 a agosto de 2018. Se describen las variables demográficas, clínicas, bioquímicas y omplicaciones durante el evento (CAD). Resultados: De los 391 pacientes 236 pacientes fueron identificados como diabéticos conocidos vs. 155 pacientes debut. Del total 59.8% mujeres vs 40.2% hombres. Si se clasifica la CAD por el valor de pH el porcentaje de pacientes con CAD leve es del 43,7 % seguido por la CAD moderada 25,6 % y la CAD severa 30,7%, mientras que si se clasifica por el valor de bicarbonato los casos de CAD son predominantemente moderados con un 43.1%, seguidos por la CAD severa con un 28.3% y leve un 28,1 %. La estancia de los pacientes con debut de CAD es mayor tanto en hospitalización como en la unidad de cuidado intensivo. Conclusión: La CAD tiene un comportamiento metabólico y un grado de severidad diferente de acuerdo a la variable utilizada para clasificarlo sea pH o bicarbonato, utilizar los valores de bicarbonato permiten clasificar bioquímicamente de manera más especifica el trastorno, la complicación mas frecuente fue el edema cerebral y se presenta en los casos de CAD grave. La estancia hospitalaria es mayor en los casos de CAD grave.spa
dc.description.abstractIntroduction: Diabetic ketoacidosis (CAD) in pediatrics is a common complication of diabetes mellitus type 1 (DM-1). Several factors influence the response to treatment and its metabolic behavior may vary according to whether the diabetic is known or is a debut. Objective: We describe the variables associated with CAD in patients under 18 years of age, including demographic, clinical, paraclinical characteristics, hospital stay and complications. Materials and methods: Cross-sectional study of a sample of 391 pediatric patients stratified by severity of CAD on admission between July 2007 and August 2018. Demographic, clinical, biochemical and omplications during the event (CAD) are described. Results: Of the 391 patients, 236 patients identified as known diabetics. 155 patients debut. Of the total 59.8% women vs 40.2% men. If CAD is classified by the pH value, the percentage of patients with mild CAD is 43.7% followed by moderate CAD 25.6% and severe CAD 30.7%, while if it is classified by the value of bicarbonate cases of CAD are predominantly moderate with 43.1%, followed by severe CAD with 28.3% and slight 28.1%. The stay of patients with CAD debut is greater both in hospitalization and in the intensive care unit. Conclusion: CAD has a different metabolic behavior and a degree of severity according to the variable used to classify it either pH or bicarbonate, using the bicarbonate values allows biochemically classifying the disorder more specifically, the most frequent complication was cerebral edema and it occurs in cases of severe CAD. The hospital stay is longer in cases of severe CAD.spa
dc.description.embargo2021-02-12 01:01:01: Script de automatizacion de embargos. info:eu-repo/date/embargoEnd/2021-02-11
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.48713/10336_19035
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/19035
dc.language.isospa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentFacultad de medicinaspa
dc.publisher.programEspecialización en Cuidado Intensivo Pediátricospa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
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dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectCetoacidosisspa
dc.subjectDiabetes mellitusspa
dc.subjectAcidosis metabólicaspa
dc.subjectNiñosspa
dc.subjectTratamientospa
dc.subject.ddcGinecología & otras especialidades médicasspa
dc.subject.keywordKetoacidosiseng
dc.subject.keywordMellitus diabeteseng
dc.subject.keywordMetabolic acidosiseng
dc.subject.keywordMetabolic acidosisspa
dc.subject.keywordtreatment.eng
dc.subject.keywordTreatmentspa
dc.subject.lembDiabetes en niñosspa
dc.subject.lembCetosisspa
dc.titleCaracterización de pacientes pediátricos con cetoacidosis diabética de acuerdo a la presentación de la diabetes mellitus en hospitales de Colombia, 2017 – 2018spa
dc.typemasterThesiseng
dc.type.documentDescriptivo observacional retrospectivospa
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTrabajo de gradospa
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