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Sensibilidad de la dosis de prueba epidural para detectar inyección intravascular: meta-análisis

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dc.contributor.advisorGonzález Díaz, Jairo
dc.contributor.advisorRodríguez Sánchez, Geovanny
dc.creatorAyarza Pulido, Gustavo
dc.creatorGiraldo Ariza, Luisa Fernanda
dc.creator.degreeEspecialista en Anestesiología HOK
dc.date.accessioned2017-08-29T19:26:09Z
dc.date.available2017-08-29T19:26:09Z
dc.date.created2017-07-24
dc.date.issued2017
dc.descriptionLa presente revisión sistemática surge como estrategia para resumir la evidencia disponible en torno a la realización de la dosis de prueba y su validez evaluando la sensibilidad, como método para detectar la inyección intravascular epidural inadvertida.spa
dc.description.abstractEpidural test dose is a procedure that allows detecting inadvertent intravascular injection. The aim of this study is to systematically review and summarize available evidence regarding the performance of test dose and its value as a method for detecting inadvertent epidural intravascular injection. METHODS: Two reviewers independently extracted relevant data from studies that met inclusion criteria. The published data of the validity of the test were presented and the sensitivity was scored and summarized as well as the maximum adrenergic response and the time in which this one is reached. In order to evaluate associations between measures of interest and variables such as type of measurement, mean age, type of induction and halogen a multilevel meta-regression model was fitted. RESULTS: From 758 studies, 21 randomized double-blind clinical trials were selected, in which 15 μg epinephrine versus placebo or lidocaine without epinephrine were administered intravenously. A sensitivity of 99. 8% (95% CI 97. 4-100%) was found for the T wave voltage decrease ≥25%, 99. 2% (95% CI 97. 5-100%) for the systolic blood pressure(increase ≥ 15 mmHg), 96, 1% (95% CI 93. 2-98 , 3%) for the modified heart rate criterion (increase ≥ 10 bpm) and 84. 6% (95% CI 79, 5-89. 1%) for the standard heartrate criterion (increase ≥20 bpm). The specifity was a 100% in most cases. DISCUSSION: The epidural test dose reaches a global mayor sensitivity of 84%, although it may be affected by age, anesthesia characteristics and type of measurement. Inter-study differences, risk of bias, and publication bias require caution in taking these results. eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.48713/10336_13725
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/13725
dc.language.isospa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentFacultad de Medicinaspa
dc.publisher.programEspecialización en Anestesiología HOKspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto completo)spa
dc.rights.ccAtribución-NoComercial-SinDerivadas 2.5 Colombiaspa
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dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
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dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectAnalgesia epiduralspa
dc.subjectHumanosspa
dc.subjectInyección epiduralspa
dc.subjectEpinefrinaspa
dc.subject.ddcVarias ramas de la medicina, Cirugía
dc.subject.decsAnestesiologíaspa
dc.subject.decsAnestesia epiduralspa
dc.subject.decsPruebas de toxicidadspa
dc.subject.keywordAnalgesia epiduraleng
dc.subject.keywordHumanseng
dc.subject.keywordInjections epiduraleng
dc.subject.keywordpinephrineeng
dc.subject.lembAnestesiologíaspa
dc.titleSensibilidad de la dosis de prueba epidural para detectar inyección intravascular: meta-análisisspa
dc.typemasterThesiseng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTrabajo de gradospa
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