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Enalapril versus nifedipino para el manejo de la hipertensión arterial postparto

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dc.contributor.advisorGómez Polanía, Omar Leonardo
dc.creatorMonroy Muñoz, Ricardo
dc.creator.degreeEspecialista en Ginecología y Obstericia
dc.date.accessioned2014-02-12T15:21:33Z
dc.date.available2014-02-12T15:21:33Z
dc.date.created2013-01-05
dc.date.issued2013
dc.descriptionIntroducción: Los desórdenes hipertensivos en el embarazo son la mayor causa de morbimortalidad materna en el mundo, su tratamiento habitualmente se realiza con nifedipino o enalapril durante el postparto indistintamente, pero no hay estudios que los comparen. Metodología: Se realizó un estudio de corte transversal con fines analíticos en el cual se incluyeron las historias clínicas de pacientes con trastorno hipertensivo durante el postparto que recibieron alguno de estos dos medicamentos y se evaluó el control de tensión arterial, necesidad de otros antihipertensivos, efectos adversos, presencia de complicaciones en ambos grupos. Resultados: Se estudió una muestra representativa, homogénea de 139 pacientes (p 0,43). Todas controlaron las cifras tensionales con el medicamento recibido. El 45% (n=62) recibió enalapril 20 mg cada 12 horas, el 40% (n=56) recibió nifedipino 30 mg cada 8 horas, el 15% (n=21) recibió nifedipino 30 mg cada 12 horas. No se presentaron efectos adversos, complicaciones o mortalidad en ninguno de los grupos. Las pacientes con enalapril requirieron más antihipertensivos comparado con las pacientes que recibieron nifedipino con diferencia estadísticamente significativa (p 0,001). Discusión La escogencia de un antihipertensivo durante el postparto debe estar encaminada al tipo de trastorno antihipertensivo: aquellos que se presentan por primera vez durante el embarazo se les administra nifedipino con excelentes resultados; aquellos con antecedente de hipertensión previa se les administra enalapril con buenos resultados. Ambos medicamentos controlaron la presión arterial adecuadamente sin complicaciones ni mortalidad.spa
dc.description.abstractIntroduction: Hypertensive disorders during pregnancy are a major cause of maternal morbidity and mortality worldwide, and its treatment postpartumis usually performed with nifedipine or enalapril interchangeably, but there are no studies that compare one with another. Methods: I conducted a cross sectional study with analytical purposes which included clinical records of patients with hypertensive disorder during the postpartum who received either of these two drugs and the variables to evaluate were blood pressure control, need for additional antihypertensive effects, presence of complications in both groups. Results : We studied a homogeneous sample of 139 patients ( p 0,43 ) . All the patients controlled the blood pressure with the medication received . The 45% (n = 62) received enalapril 20 mg bid, 40% ( n = 56 ) received nifedipine 30 mg tid, 15% (n = 21) received nifedipine 30 mg bid. There were no side effects, complications or mortality in either group . The patients receiving enalapril required more antihypertensive compared with patients who received nifedipine with statistically significant difference ( p 0.001 ) . Discussion The choice of an antihypertensive during postpartum should be directed depending on the type of hypertensive disorder: those presenting for the first time during pregnancy nifedipine is administered with excellent results, those with a history of previous hypertension enalapril is administered with good results. Both drugs controlled blood pressure adequately without complications or mortality.eng
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dc.format.tipoDocumentospa
dc.identifier.doihttps://doi.org/10.48713/10336_4941
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/4941
dc.language.isospa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentFacultad de Medicinaspa
dc.publisher.programEspecialización en Ginecología y Obstericiaspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto completo)spa
dc.rights.ccAtribución-NoComercial-SinDerivadas 2.5 Colombiaspa
dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma.spa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
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dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectantihipertensivosspa
dc.subjecthipertensión durante postpartospa
dc.subjectnifedipinospa
dc.subjectenalaprilspa
dc.subject.decsANTIHIPERTENSIVOSspa
dc.subject.decsENALAPRIL - ADMINISTRACIÓN & DOSIFICACIÓNspa
dc.subject.decsHIPERTENSIÓN EN EL EMBARAZO - TRATAMIENTOspa
dc.subject.decsNIFEDIPINO - ADMINISTRACIÓN & DOSIFICACIÓNspa
dc.subject.keywordantihypertensiveeng
dc.subject.keywordhypertension during postpartumeng
dc.subject.keywordnidepineeng
dc.subject.keywordenalaprileng
dc.titleEnalapril versus nifedipino para el manejo de la hipertensión arterial postpartospa
dc.typemasterThesiseng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTrabajo de gradospa
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