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How does age at onset influence the outcome of autoimmune diseases?

dc.audienceComunidad Rosaristaspa
dc.creatorAmador-Patarroyo, Manuel-José
dc.creatorRodríguez-Rodríguez, Alberto
dc.creatorMontoya-Ortiz, Gladis
dc.creator.googleAmador-Patarroyo, Manuel-José
dc.creator.googleRodríguez-Rodríguez, Alberto
dc.creator.googleMontoya-Ortiz, Gladis
dc.date.accessioned2014-08-11T19:40:36Z
dc.date.available2014-08-11T19:40:36Z
dc.date.created2012
dc.date.issued2012
dc.description.abstractThe age at onset refers to the time period at which an individual experiences the first symptoms of a disease. In autoimmune diseases (ADs), these symptoms can be subtle but are very relevant for diagnosis. They can appear during childhood, adulthood or late in life and may vary depending on the age at onset. Variables like mortality and morbidity and the role of genes will be reviewed with a focus on the major autoimmune disorders, namely, systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes mellitus (T1D), Sjögren's syndrome, and autoimmune thyroiditis (AITD). Early age at onset is a worst prognostic factor for some ADs (i.e., SLE and T1D), while for others it does not have a significant influence on the course of disease (i.e., SS) or no unanimous consensus exists (i.e., RA and MS).eng
dc.format.mediumRecurso electrónicospa
dc.format.mimetypeapplication/pdf
dc.format.tipoDocumentospa
dc.identifier.doihttps://doi.org/doi:10.1155/2012/251730
dc.identifier.issnISSN:2090-0430
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/8776
dc.language.isoeng
dc.publisherUniversidad del Rosariospa
dc.relation.citationTitleAutoimmune Diseases
dc.relation.ispartofAutoimmune Diseases, ISSN 2090-04-30, 2012spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto completo)spa
dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma.spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectGenéticaspa
dc.subjectInmunologíaspa
dc.subjectEnfermedades autoinmunesspa
dc.subject.ddcEnfermedades
dc.subject.decsEnfermedades autoinmunesspa
dc.subject.decsGenéticaspa
dc.subject.decsInmunologíaspa
dc.titleHow does age at onset influence the outcome of autoimmune diseases?spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaArtículospa
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