Ítem
Acceso Abierto
Impacto de dos técnicas quirúrgicas sobre la recaída local de carcinoma de mama en pacientes de una clínica de Bogotá D.C.
| dc.contributor.advisor | Trillos Peña, Carlos Enrique | |
| dc.creator | Zuluaga, Clarena | |
| dc.creator | Morales, Vanesa | |
| dc.creator | Robledo, José Fernando | |
| dc.creator | Hernandez, Diana | |
| dc.creator.degree | Especialista en Epidemiología (en Convenio con el CES) | |
| dc.date.accessioned | 2014-11-18T12:57:11Z | |
| dc.date.available | 2014-11-18T12:57:11Z | |
| dc.date.created | 2014-11-08 | |
| dc.date.issued | 2014 | |
| dc.description | Introducción: El carcinoma de mama es el tumor maligno más frecuente entre las mujeres y representa una significativa mortalidad en los países en vías de desarrollo. Según datos del Instituto Nacional de Cancerología en el 2010 se reportaron 672 nuevos casos de cáncer de mama, lo que representó el 18% de todos los tumores malignos en mujeres. Durante las últimas 3 décadas las técnicas quirúrgicas para el tratamiento del cáncer de mama han presentado un cambio significativo y proponen disminución de procedimientos agresivos y radicales, intervenciones como: mastectomía radical modificada, cirugía conservadora y la disección de ganglio centinela son ejemplos claros de esta evolución asociado al incremento de la reconstrucción mamaria inmediata. Metodología: Estudio observacional tipo cohorte retrospectivo en el cual se revisó una base de datos de pacientes con cáncer de mama de las cuales 632 fueron sometidas a mastectomía radical con preservación de piel y complejo areola-pezón y mastectomía radical con preservación de piel sin preservación del complejo areola-pezón, los dos procedimientos asociados a reconstrucción mamaria inmediata y se comparó la frecuencia de recaída local entre los dos grupos. Resultados: De las 632 pacientes estudiadas al 30.5% se les realizo preservación del complejo areola pezón. Las mujeres a quienes se les realizó preservación del complejo areola pezón presentaron menor sobrevida a la recaída local a 10 años (80.51%) comparado con las mujeres a quienes no se les preservó el complejo areola pezón (87.40%), sin embargo no se encontró diferencia estadísticamente significativa para determinar que las probabilidades de sobrevida sean diferentes. Discusión: No se evidenció diferencia estadísticamente significativa entre los 2 procedimientos quirúrgicos (con y sin preservación del complejo areola pezón) en relación a la recaída local, estudios retrospectivos no han evidenciado una mayor tasa de recaídas locales en pacientes a quienes se les preserva el complejo areola-pezón, sin embargo hacen falta estudios prospectivos y aleatorizados que puedan otorgar un mayor sustento científico que garantice la seguridad de la preservación del complejo areola-pezón. | spa |
| dc.description.abstract | Introduction: Breast carcinoma is the most common malignancy among women and accounts for significant mortality in developing countries. According to the National Cancer Institute in 2010; 672 new cases of breast cancer were reported, representing 18% of all malignancies in women. During the last 3 decades the surgical treatment of breast cancer techniques have a significant evolution and demonstrate reduction of agressive procedures and radical interventions such as modified radical mastectomy, conservative surgery and sentinel node dissection are clear examples of this evolution associated with immediate breast reconstruction. Methods: Retrospective observational cohort study. We review a database of 632 patients with breast cancer that underwent skin sparing mastectomy and skin sparing mastectomy with conservation of the nipple- areola complex both procedures with immediate breast reconstruction. The frequency of local recurrence between the two groups was compared. Results: 30.5% of 632 patients underwent skin sparing mastectomy with conservation of the nipple-areola complex. Women who were treated with conservation of the nipple areola complex exhibit lower survival rates to local recurrence through 10 years of follow up (80.51%) compared with women without conservation of the nipple areola complex (87.40%), this difference was not statistically significant in determining that chances of survival are different. Discussion: We found no statistically significant difference between the 2 surgical procedures (with and without preservation of the nipple areola complex) in relation to local recurrence, retrospective studies have not shown a higher rate of local recurrence in patients who are intervened with preservation of the nipple- areola complex, however there is a need of prospective randomized studies that can provide better scientific support to ensure the oncologic safety of preserving the nipple-areola complex. | eng |
| dc.format.mimetype | application/pdf | |
| dc.identifier.doi | https://doi.org/10.48713/10336_9020 | |
| dc.identifier.uri | http://repository.urosario.edu.co/handle/10336/9020 | |
| dc.language.iso | spa | |
| dc.publisher | Universidad del Rosario | spa |
| dc.publisher.department | Facultad de medicina | spa |
| dc.rights.accesRights | info:eu-repo/semantics/openAccess | |
| dc.rights.acceso | Abierto (Texto completo) | spa |
| dc.rights.cc | Atribución-NoComercial-SinDerivadas 2.5 Colombia | spa |
| dc.rights.licencia | EL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos. | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | |
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| dc.source.instname | instname:Universidad del Rosario | spa |
| dc.source.reponame | reponame:Repositorio Institucional EdocUR | spa |
| dc.subject | Breast neoplasm | spa |
| dc.subject | breast cancer | spa |
| dc.subject | skin sparing mastectomy | spa |
| dc.subject | nipple sparing mastectomy | spa |
| dc.subject | lumpectomy | spa |
| dc.subject | local recurrence neoplasm. | spa |
| dc.subject.ddc | Ginecología & otras especialidades médicas | |
| dc.subject.decs | Adenocarcinoma | spa |
| dc.subject.decs | Neoplasias de la mama | spa |
| dc.subject.decs | Cirugía | spa |
| dc.subject.decs | Epidemiología | spa |
| dc.subject.keyword | Breast neoplasm | eng |
| dc.subject.keyword | breast cancer | eng |
| dc.subject.keyword | skin sparing mastectomy | eng |
| dc.subject.keyword | nipple sparing mastectomy | eng |
| dc.subject.keyword | lumpectomy | eng |
| dc.subject.keyword | local recurrence neoplasm. | eng |
| dc.title | Impacto de dos técnicas quirúrgicas sobre la recaída local de carcinoma de mama en pacientes de una clínica de Bogotá D.C. | spa |
| dc.type | bachelorThesis | eng |
| dc.type.hasVersion | info:eu-repo/semantics/acceptedVersion | |
| dc.type.spa | Trabajo de grado | spa |
