@mastersthesis{10336/30637,
author = {Torres Zea, Yenica Stefany},
author = {Castiblanco Rodriguez, Jeisson Fernando},
url = {https://repository.urosario.edu.co/handle/10336/30637},
abstract = {Introduction: Alzheimer's disease (AD) is a serious and insidious pathology, which involves an irreversible catastrophic neurodegenerative process that ends with death. The origin of AD is not due to a single etiological reason but is due to various natures that can range from genetic alterations, environmental influence, lifestyles, and demographic conditions such as sex and education. Objective: To describe the relationship between educational level and age of onset of Alzheimer's disease. Methods: Systematic literature review. A search for analytical observational studies and a gray literature search was performed. The risk of bias was assessed by applying the critical appraisal instruments developed by the Joanna Briggs Institute. Results: Seven studies were selected, six used a cross-sectional design and one a case-control study nested in a cohort. The educational level of the subjects varied between 0 and 19 years of formal schooling. The average age of onset of dementia caused by Alzheimer's disease ranged from 67.3 to 86.5 years. Seven studies were selected, six used a cross-sectional design and a nested case-control study in a cohort. None of the studies report sample calculation. The diagnosis of Alzheimer's disease was based on the NINCDS, DSM-IV, and NIA-AA criteria. 70% of the study subjects were women. The educational level of the subjects ranged from 0 to 19 years of formal schooling. The women, African Americans and Hispanics being the population groups with the lowest academic level. The average age of onset of dementia caused by Alzheimer's disease ranged from 67.3 to 86.5 years. No significant differences were found between the age of onset of dementia between men and women. Conclusions: There is no consensus or sufficient evidence to ensure an association between educational level and the age of onset of sporadic Alzheimer's disease. A higher level of evidence is necessary to establish the association between these variables.},
keywords = {Enfermedad de Alzheimer},
keywords = {Correlación nivel educativo padecimiento de Alzheimer},
keywords = {Pre-valencia de demencia en mujeres},
keywords = {Edad de inicio de la enfermedad de Alzheimer},
title = {Relación entre nivel educativo y edad de aparición de la enfermedad de Alzheimer, revisión sistemática},
publisher = {Universidad del Rosario},
keywords = {Alzheimer's disease},
keywords = {Educational level correlation with Alzheimer's disease},
keywords = {Prevalence of dementia in women},
keywords = {Age of onset of Alzheimer's disease},
}