@bachelorthesis{10336/32810,
author = {Rios Barajas, Luisa Fernanda},
author = {Murcia Gutierrez, Anngie Liseth},
author = {Diaz Ardila, Maria Catalina},
year = {2021},
month = {9},
url = {https://repository.urosario.edu.co/handle/10336/32810},
abstract = {Background: After a year and a half since the start of the pandemic due to the new COVID-19 virus, there is insufficient information about the association of the predictive mortality scales usually used in critically ill patients admitted to the Care Unit Intensive. Objective: The objective of the study was to evaluate the prognostic performance of death of the APACHE-II, CURB-65 and SOFA scales in patients with SARS CoV2 infection admitted to the Intensive Care Unit in critical condition of Hospital El Tunal - Subred Integrated Health Services South. Methods: A study of diagnostic tests was carried out, using records of critically ill patients diagnosed with COVID-19 at El Tunal Hospital in the city of Bogotá D.C between September and December 2020. A descriptive analysis and frequency tables were performed to characterize and summarize the clinical information of the study population. ROC (Receiver operating feature) curves were constructed to evaluate the performance of each scale, the areas under the curve were analyzed and the cut-off points were taken based on the best evaluated sensitivity and specificity. In addition, the Youden Index, the positive and negative predictive values and the positive and negative likelihood ratio were calculated for each one. Results: It was obtained as a result that the SOFA scale had a better prognostic performance, demonstrating an acceptable AUC of 0.70 with a 95% CI between 0.64-0.75 with a sensitivity and specificity of 83.6% and 52.2% respectively. taking 5.5 as the cut-off point. Regarding the CURB-65 scale, an AUC of 0.68 (95% CI 0.62-0.74) and a sensitivity of 73.6% and a specificity of 55.9% were obtained, taking a cut-off point of 1.5. finally, the APACHE-II scale showed an AUC of 0.65 (95% CI 0.60-0.71), a sensitivity of 51.6% and a specificity of 70.2% for a cut-off point of 14.5.},
keywords = {Paciente crítico enfermo},
keywords = {Enfermedad del coronavirus 2019},
keywords = {SARS-CoV2},
keywords = {Cohorte retrospectiva},
keywords = {Sistemas de puntuación rápida},
keywords = {Escalas de predicción de mortalidad},
keywords = {APACHE},
keywords = {CURB65},
keywords = {SOFA},
title = {Desempeño de las escalas APACHE-II, SOFA y CURB-65 para pronóstico de muerte en el paciente críticamente enfermo con covid-19 de las unidades de cuidado intensivo en un hospital de referencia en la ciudad de Bogotá, en una cohorte retrospectiva del año 2020},
publisher = {Universidad del Rosario},
keywords = {Critically ill patient},
keywords = {Coronavirus disease 2019},
keywords = {SARS-CoV2},
keywords = {Retrospective cohort},
keywords = {Rapid scoring systems},
keywords = {Mortality prediction scales},
keywords = {APACHE},
keywords = {CURB65},
keywords = {SOFA},
}