TY  - JOUR
T1  - Deciphering the introduction and transmission of SARS-CoV-2 in the Colombian Amazon Basin
A1  - Ballesteros, Nathalia
A1  - Muñoz, Marina
A1  - Patiño, Luz Helena
A1  - Hernández, Carolina
A1  - González-Casabianca, Felipe
A1  - Carroll, Iván
A1  - Santos-Vega, Mauricio
A1  - Cascante, Jaime
A1  - Angel, Andrés
A1  - Feged-Rivadeneira, Alejandro
A1  - Palma-Cuero, Mónica
A1  - Flórez, Carolina
A1  - Gomez, Sergio
A1  - van de Guchte, Adriana
A1  - Khan, Zenab
A1  - Dutta, Jayeeta
A1  - Obla, Ajay
A1  - Alshammary, Hala Alejel
A1  - Gonzalez-Reiche, Ana S.
A1  - Hernandez, Matthew M.
A1  - Sordillo, Emilia Mia
A1  - Simon, Viviana
A1  - van Bakel, Harm
A1  - Paniz-Mondolfi, Alberto E.
A1  - Ramírez, Juan David
Y1  - 2021/04/15
N2  - Author summary SARS-CoV-2 has dramatically impacted Amerindian native communities across South America, particularly in the Amazonian basin. In order to unveil the introduction and initial spread of this pandemic virus into this region, we conducted a genomic epidemiology study where we sequenced 59 genomes from cases in the Amazonas department of Colombia. Our results showed two independent introductions of the virus into the department, one of these associated with asymptomatic cases. This represents the first genomic epidemiology study focused on the Colombian Amazonas department where a great amount of native Amerindian indigenous communities inhabits. Our results provide insights of the transmission dynamic in this region and reported relevant information to pursue strategies to mitigate the spread of the virus in the Amazon population which currently are facing new risks due to the circulating new variant of concern P.1.
JF  - PLOS Neglected Tropical Diseases
JA  - PLOS Neglected Tropical Diseases
VL  - 15
IS  - 4
UR  - https://doi.org/10.1371/journal.pntd.0009327
SP  - e0009327
EP  - 
PB  - Public Library of Science
M3  - doi:10.1371/journal.pntd.0009327
ER  -