Now showing items 1-7 of 7

    • Association of FOXD1 variants with adverse pregnancy outcomes in mice and humans 

      Laissue, Paul; Lakha, Besma; Vatin, Magalie; Batista, Frank; Burgio, Gaetan; Mercier, Eric; Dos Santos, Esther; Buffat, Christophe; Sierra Diaz, Diana Carolina; Renault, Gilles; Montagutelli, Xavier; Salmon, Jane; Monget, Philippe; Veitia, Reiner; Meháts, Céline; Fellous, Marc; Gris, Jean-Christophe; Cocquet, Julie; Vaiman, Daniel
      Recurrent spontaneous abortion (RSA) is a common cause of infertility, but previous attempts at identifying RSA causative genes have been relatively unsuccessful. Such failure to describe RSA aetiological genes might be ...
       Artículo. 2016
    • "FOXD1 mutations are related to repeated implantation failure, intra-uterine growth restriction and preeclampsia" 

      Quintero-Ronderos, Paula; Jiménez, Karen Marcela; Esteban-Pérez, Clara; Ojeda, Diego A.; Bello, Sandra; Fonseca, Dora Janeth; Coronel, María Alejandra; Moreno-Ortiz, Harold; Sierra-Díaz, Diana Carolina; Lucena, Elkin; Barbaux, Sandrine; Vaiman, Daniel; Laissue, Paul
      "Background: Human reproductive disorders consist of frequently occurring dysfunctions including a broad range of phenotypes affecting fertility and women's health during pregnancy. Several female-related diseases have ...
       Artículo. 2019
    • Genome-Wide Linkage in a Highly Consanguineous Pedigree Reveals Two Novel Loci on Chromosome 7 for Non-Syndromic Familial Premature Ovarian Failure 

      Caburet, Sandrine; Zavadakova, Petra; Ben-Neriah, Ziva; Bouhali, Kamal; Dipietromaria, Aurélie; Charon, Céline; Besse, Céline; Laissue, Paul; Chalifa-Caspi, Vered; Christin-Maitre, Sophie; Vaiman, Daniel; Levi, Giovanni; Veitia, Reiner; Fellous, Marc
      Background: The human condition known as Premature Ovarian Failure (POF) is characterized by loss of ovarian function before the age of 40. A majority of POF cases are sporadic, but 10–15% are familial, suggesting a genetic ...
       Artículo. 2012
    • Novel genes and mutations in patients affected by recurrent pregnancy loss 

      Quintero-Ronderos, Paula; Mercier, Eric; Fukuda, Michiko; González, Ronald; Suárez, Carlos Fernando; Alfonso Patarroyo, Manuel; Vaiman, Daniel; Gris, Jean-Christophe; Laissue, Paul
      Recurrent pregnancy loss is a frequently occurring human infertility-related disease affecting ~1% of women. It has been estimated that the cause remains unexplained in >50% cases which strongly suggests that genetic ...
       Artículo. 2017
    • Polymorphisms of human placental alkaline phosphatase are associated with in vitro fertilization success and recurrent pregnancy loss 

      Vatin, Magalie; Bouvier, Sylvie; Bellazi, Linda; Montagutelli, Xavier; Laissue, Paul; Ziyyat, Ahmed; Serres, Catherine; De Mazancourt, Philippe; Dieudonné, Marie-Noelle; Mornet, Etienne; Vaiman, Daniel; Gris, Jean-Christophe
      "Fertility is a quantitative, complex character governed by a considerable number of genes. Despite clinical and scientific advances, several cases of human infertility remain unexplained. In the present study, using a ...
       Artículo. 2014
    • Refined mapping of a quantitative trait locus on chromosome 1 responsible for mouse embryonic death 

      Vatin, Magalie; Burgio, Gaetan; Renault, Gilles; Laissue, Paul; Firlej, Virginie; Mondon, Françoise; Montagutelli, Xavier; Vaiman, Daniel; Serres, Catherine; Ziyyat, Ahmed
      Recurrent spontaneous abortion (RSA) is defined as the loss of three or more consecutive pregnancies during the first trimester of embryonic intrauterine development. This kind of human infertility is frequent among the ...
       Artículo. 2012
    • THBD sequence variants potentially related to recurrent pregnancy loss 

      Quintero-Ronderos, Paula; Mercier, Eric; Gris, Jean-Christophe; Esteban-Perez, Clara; Moreno-Ortiz, Harold; Fonseca, Dora Janeth; Lucena, Elkin; Vaiman, Daniel; Laissue, Paul
      "Recurrent pregnancy loss (RPL) is a frequently occurring disease, which is classified as idiopathic in more than 50% of cases. THBD, the endothelial cell receptor for thrombin, has been associated with distinct biological ...
       Artículo. 2017