Now showing items 1-10 of 10

    • A latent genetic subtype of major depression identified by whole-exome genotyping data in a Mexican-American cohort 

      Yu, C.; Arcos-Burgos, Mauricio; Licinio, Julio; Wong, M-L
      Identifying data-driven subtypes of major depressive disorder (MDD) is an important topic of psychiatric research. Currently, MDD subtypes are based on clinically defined depression symptom patterns. Although a few data-driven ...
       Artículo. 2017
    • ADGRL3 (LPHN3) variants predict substance use disorder 

      Arcos-Burgos, Mauricio ; Vélez, Jorge I.; Martinez, Ariel F.; Ribasés, Marta; Ramos-Quiroga, Josep A.; Sánchez-Mora, Cristina; Richarte, Vanesa; Roncero, Carlos; Cormand, Bru; Fernández-Castillo, Noelia; Casas, Miguel; Lopera, Francisco; Pineda, David A.; Palacio, Juan D.; Acosta-López, Johan E.; Cervantes-Henriquez, Martha L.; Sánchez-Rojas, Manuel G.; Puentes-Rozo, Pedro J.; Molina, Brooke S. G.; Boden, Margaret T.; Wallis, Deeann; Lidbury, Brett; Newman, Saul; Easteal, Simon; Swanson, James; Patel, Hardip; Volkow, Nora; Acosta, Maria T.; Castellanos, Francisco X.; de Leon, Jose; Mastronardi, Claudio A.; Muenke, Maximilian
      "Genetic factors are strongly implicated in the susceptibility to develop externalizing syndromes such as attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder, conduct disorder, and substance use ...
       Artículo. 2019
    • "Candidate gene discovery in autoimmunity by using extreme phenotypes, next generation sequencing and whole exome capture" 

      Johar, Angad S.; Anaya, Juan-Manuel; Andrews, Dan; Patel, Hardip R.; Field, Matthew; Goodnow, Chris; Arcos-Burgos, Mauricio
      "Whole exome sequencing (WES) is a widely used strategy for detection of protein coding and splicing variants associated with inherited diseases. Many studies have shown that the strategy has been broad and proficient due ...
       Artículo. 2015
    • Low-frequency and rare variants may contribute to elucidate the genetics of major depressive disorder 

      Yu, Chenglong; Arcos-Burgos, Mauricio; Baune, Bernhard T.; Arolt, Volker; Dannlowski, Udo; Wong, Ma-Li; Licinio, Julio
      Major depressive disorder (MDD) is a common but serious psychiatric disorder with significant levels of morbidity and mortality. Recent genome-wide association studies (GWAS) on common variants increase our understanding ...
       Artículo. 2018
    • Novel and rare functional genomic variants in multiple autoimmune syndrome and Sjögren's syndrome 

      Johar, Angad S; Mastronardi, Claudio; Rojas-Villarraga, Adriana; Patel, Hardip R; Chuah, Aaron; Peng, Kaiman; Higgins, Angela; Milburn, Peter; Palmer, Stephanie; Silva‑Lara, Maria Fernanda; Velez, Jorge I; Andrews, Dan; Field, Matthew; Huttley, Gavin; Goodnow, Chris; Anaya, Juan-Manuel; Arcos-Burgos, Mauricio
      Background: Multiple autoimmune syndrome (MAS), an extreme phenotype of autoimmune disorders, is a very well suited trait to tackle genomic variants of these conditions. Whole exome sequencing (WES) is a widely used strategy ...
       Artículo. 2015
    • Retrospective assessment of childhood ADHD symptoms for diagnosis in adults: validity of a short 8-item version of the Wender-Utah Rating Scale 

      Vélez, Jorge I; Acosta, María T.; Muenke, Maximilian; Arcos-Burgos, Mauricio ; Easteal, Simón
      "The Wender-Utah Rating Scale (WURS) is a widely used self-report instrument for retrospective assessment of childhood ADHD. However, many WURS items are not specific to ADHD. Here, we investigated the effect of excluding ...
       Artículo. 2016
    • Targeting neuroplasticity, cardiovascular, and cognitive-associated : Genomic variants in familial alzheimer’s disease 

      Vélez, Jorge I.; Lopera, Francisco; Creagh, Penelope K.; Piñeros, Laura B.; Das, Debjani; Cervantes-Henríquez, Martha L.; Acosta-López, Johan E.; Isaza-Ruget, Mario A.; Espinosa, Lady G.; Easteal, Simon; Quintero-Hernandez, Gustavo-Adolfo; Tamar Silva, Claudia; Mastronardi, Claudio; Arcos-Burgos, Mauricio
      The identification of novel genetic variants contributing to the widespread in the age of onset (AOO) of Alzheimer’s disease (AD) could aid in the prognosis and/or development of new therapeutic strategies focused on early ...
       Artículo. 2018
    • Uveitis and Multiple Sclerosis: Potential Common Causal Mutations 

      de-la-Torre, Alejandra; Silva-Aldana, Claudia T.; Muñoz-Ortiz, Juliana; Piñeros-Hernández, Laura B.; Otero, Oscar; Domínguez, Alejandra; Faciolince, León A.; Arcos-Holzinger, Mauricio; Mastronardi, Claudio; Contreras-Bravo, Nora Constanza; Restrepo, Carlos M.; Arcos-Burgos, Mauricio
      "Uveitis, defined as inflammation of the uveal tract of the eye, is a leading cause of blindness and visual impairment throughout the world. The etiology of uveitis is complex, and autoimmunity plays a major role in its ...
       Artículo. 2019
    • What is next after the genes for autoimmunity? 

      Castiblanco, John; Arcos-Burgos, Mauricio; Anaya, Juan-Manuel
      Clinical pathologies draw us to envisage disease as either an independent entity or a diverse set of traits governed by common physiopathological mechanisms, prompted by environmental assaults throughout life. Autoimmune ...
       Artículo. 2013
    • "Young adult outcomes in the follow-up of the multimodal treatment study of attention-deficit/hyperactivity disorder: symptom persistence, source discrepancy, and height suppression" 

      Swanson, James M.; Arnold, L. Eugene; Molina, Brooke S.G.; Sibley, Margaret H.; Hechtman, Lily T.; Hinshaw, Stephen P.; Abikoff, Howard B.; Stehli, Annamarie; Owens, Elizabeth B.; Mitchell, John T.; Nichols, Quyen; Howard, Andrea; Greenhill, Laurence L.; Hoza, Betsy; Newcorn, Jeffrey H.; Jensen, Peter S.; Vitiello, Benedetto; Wigal, Timothy; Epstein, Jeffery N.; Tamm, Leanne; Lakes, Kimberly D.; Waxmonsky, James; Lerner, Marc; Etcovitch, Joy; Murray, Desiree W.; Muenke, Maximilian; Acosta, Maria T.; Arcos-Burgos, Mauricio ; Pelham, William E.; Kraemer, Helena C.
      "Background: The Multimodal Treatment Study (MTA) began as a 14-month randomized clinical trial of behavioral and pharmacological treatments of 579 children (7–10 years of age) diagnosed with attention-deficit/hyperactivity ...
       Artículo. 2017