Now showing items 1-3 of 3

    • A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy 

      Tamar Silva, Claudia; Zorkoltseva, Irina V.; Niemeijer, Maartje N.; van den Berg, Marten E.; Amin, Najaf; Demirkan, Ayşe; Leeuwen, Elisa van; Iglesias, Adriana I.; Piñeros-Hernández, Laura B.; Restrepo, Carlos M.; Kors, Jan A.; Kirichenko, Anatoly V.; Willemsen, Rob; Oostra, Ben A.; Stricker, Bruno H.; Uitterlinden, André G.; Axenovich, Tatiana I.; Duijn, Cornelia M. van; Isaacs, Aaron
      Background: Electrocardiographic measures of left ventricular hypertrophy (LVH) are used as predictors of cardiovascular risk. We combined linkage and association analyses to discover novel rare genetic variants involved ...
       Artículo. 2018
    • Heritabilities, proportions of heritabilities explained by GWAS findings, and implications of cross-phenotype effects on PR interval 

      Tamar Silva, Claudia; Kors, Jan A.; Amin, Najaf; Dehghan, Abbas; Witteman, Jacqueline C. M.; Willemsen, Rob; Oostra, Ben A.; van Duijn, Cornelia; Isaacs, Aaron
      Electrocardiogram (ECG) measurements are a powerful tool for evaluating cardiac function and are widely used for the diagnosis and prediction of a variety of conditions, including myocardial infarction, cardiac arrhythmias, ...
       Artículo. 2015
    • Targeting neuroplasticity, cardiovascular, and cognitive-associated : Genomic variants in familial alzheimer’s disease 

      Vélez, Jorge I.; Lopera, Francisco; Creagh, Penelope K.; Piñeros, Laura B.; Das, Debjani; Cervantes-Henríquez, Martha L.; Acosta-López, Johan E.; Isaza-Ruget, Mario A.; Espinosa, Lady G.; Easteal, Simon; Quintero-Hernandez, Gustavo-Adolfo; Tamar Silva, Claudia; Mastronardi, Claudio; Arcos-Burgos, Mauricio
      The identification of novel genetic variants contributing to the widespread in the age of onset (AOO) of Alzheimer’s disease (AD) could aid in the prognosis and/or development of new therapeutic strategies focused on early ...
       Artículo. 2018