Now showing items 1-3 of 3

    • A combined linkage and exome sequencing analysis for electrocardiogram parameters in the erasmus rucphen family study 

      Tamar Silva, Claudia; Zorkoltseva, Irina V.; Amin, Najaf; Demirkan, Ayse; van Leeuwen, Elisabeth M.; Kors, Jan A.; van den Berg, Marten; Stricker, Bruno H.; Uitterlinden, André; Kirichenko, Anatoly V.; Witteman, Jacqueline C. M.; Willemsen, Rob; Oostra, Ben A.; Axenovich, Tatiana I.; van Duijn, Cornelia M.; Isaacs, Aaron
      Electrocardiogram (ECG) measurements play a key role in the diagnosis and prediction of cardiac arrhythmias and sudden cardiac death. ECG parameters, such as the PR, QRS, and QT intervals, are known to be heritable and ...
       Artículo. 2016
    • A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy 

      Tamar Silva, Claudia; Zorkoltseva, Irina V.; Niemeijer, Maartje N.; van den Berg, Marten E.; Amin, Najaf; Demirkan, Ayşe; Leeuwen, Elisa van; Iglesias, Adriana I.; Piñeros-Hernández, Laura B.; Restrepo, Carlos M.; Kors, Jan A.; Kirichenko, Anatoly V.; Willemsen, Rob; Oostra, Ben A.; Stricker, Bruno H.; Uitterlinden, André G.; Axenovich, Tatiana I.; Duijn, Cornelia M. van; Isaacs, Aaron
      Background: Electrocardiographic measures of left ventricular hypertrophy (LVH) are used as predictors of cardiovascular risk. We combined linkage and association analyses to discover novel rare genetic variants involved ...
       Artículo. 2018
    • Heritabilities, proportions of heritabilities explained by GWAS findings, and implications of cross-phenotype effects on PR interval 

      Tamar Silva, Claudia; Kors, Jan A.; Amin, Najaf; Dehghan, Abbas; Witteman, Jacqueline C. M.; Willemsen, Rob; Oostra, Ben A.; van Duijn, Cornelia; Isaacs, Aaron
      Electrocardiogram (ECG) measurements are a powerful tool for evaluating cardiac function and are widely used for the diagnosis and prediction of a variety of conditions, including myocardial infarction, cardiac arrhythmias, ...
       Artículo. 2015

       

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