Now showing items 1-20 of 121

    • 16/6-idiotype expressing antibodies induce brain inflammation and cognitive impairment in mice: the mosaic of central nervous system involvement in lupus 

      Shaye, Kivity; Katzav, Aviva; Arango, María-Teresa; Landau-Rabi, Moran; Zafrir, Yaron; Agmon-Levin, Nancy; Blank, Miri; Anaya, Juan-Manuel; Mozes, Edna; Chapman, Joab; Shoenfeld, Yehuda
      Background: The 16/6-idiotype (16/6-Id) of the human anti-DNA antibody was found to induce experimental lupus in naive mice, manifested by production of autoantibodies, leukopenia and elevated inflammatory markers, as well ...
       Artículo. 2013
    • A comprehensive analysis and immunobiology of autoimmune neurological syndromes during the Zika virus outbreak in Cúcuta, Colombia 

      Anaya, Juan-Manuel; Rodríguez, Yhojan; Monsalve-Carmona, Diana; Vega, Daniel; Ojeda, Ernesto; Gonzalez-Bravo, Diana; Rodríguez-Jímenez, Mónica; Pinto-Díaz, Carlos A.; Chaparro, Pablo; Gunturiz, María L.; Ansari, Aftab A.; Gershwin, M. Eric; Molano-González, Nicolas; Ramirez-Santana, Carolina; Acosta-Ampudia, Yeny
      We have focused on the epidemiology and immunobiology of Zika virus (ZIKV) infection and factors associated with the development of Guillain-Barré syndrome (GBS) and other neurological syndromes in Cúcuta, the capital of ...
       Artículo. 2017
    • Abnormality of Oct-1 DNA binding in T cells from Sjogren's syndrome patients 

      Flescher, Eliezer; Vela Roch, Norma; Ogawa, Noriyoshi; Nakabayashi, Toru; Escalante, Agustin; Anaya, Juan-Manuel
      Primary Sjögren's syndrome (SS) is an autoimmune rheumatic disease characterized by T cell hypoactivity. To understand the diminished T cell response to activation signals, we measured nucleoprotein DNA?binding activities ...
       Artículo. 1996
    • Absence of a distinctive autoantibody profile in black women with lupus nephritis: comment on the article by McCarty et al 

      Joseph, Jasmine; Anaya, Juan-Manuel; Sandifer, Michele; Scopelitis, Eve; Wilson, Wendell; Espinoza, Luis R.
      McCarty and coworkers have pointed out a distinc- tive serologic profile in black women with lupus nephritis (1). We have reviewed the autoantibody profile in 42 of our black patients with systemic lupus erythematosus ...
       Artículo. 1994
    • Acceso a la atención en salud: En busca de la medicina personalizada y el sistema P5 

      Anaya, Juan-Manuel
      Una proporción significativa de las personas con necesidades de atención médica no recurren a los servicios de salud, encuentran barreras en el uso de esos servicios, y afirman que su problema no se resuelve, lo que indica ...
       Artículo. 2014
    • An antibody profile of systemic lupus erythematosus detected by antigen microarray 

      Fattal, Ittai; Shental, Noam; Mevorach, Dror; Anaya, Juan-Manuel; Livneh, Avi; Langevitz, Pnina; Zandman?Goddard, Gisele; Pauzner, Rachel; Lerner, Miriam; Blank, Miri; Hincapie, Maria?Eugenia; Gafter, Uzi; Naparstek, Yaakov; Shoenfeld, Yehuda; Domany, Eytan; Cohen, Irun R.
      Patients with systemic lupus erythematosus (SLE) produce antibodies to many different self-antigens. Here, we investigated antibodies in SLE sera using an antigen microarray containing many hundreds of antigens, mostly ...
       Artículo. 2010
    • Anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: relation with clinical features, cytokines and HLA-DRB1 

      Correa, Paula A.; Tobón, Gabriel J.; Citera, Gustavo; Cadena , José; Schneeberger, Emilce; Camargo, José F.; Maldonado-Cocco, José A.; Anaya, Juan-Manuel
      En el presente estudio se examinó la especificidad y la sensibilidad de los anticuerpos antipéptidos citrulinados cíclicos (CCP) en pacientes latinoamericanas con artritis reumatoidea (AR), así como su relación con la ...
       Artículo. 2004
    • Anti-infectious antibodies and autoimmune-associated autoantibodies in patients with type i diabetes mellitus and their close family members 

      Krause, Ilan; Anaya, Juan-Manuel; Fraser, Abigail; Barzilai, Ori; Ram, Maya; Abad, Verónica; Arango, Alvaro; García, Jorge; Shoenfeld, Yehuda
      "Type 1 diabetes mellitus (T1DM) is an autoimmune disease with complex interactions between genetic and environmental factors. We compared antibody levels to various infectious agents and of autoimmune-associated autoantibodies ...
       Documento de conferencia. 2009
    • Assessment of quality of life in patients with diagnosis of rheumatoid arthritis 

      Anaya, Juan-Manuel; Vinaccia, Stefano; Tobón, Sergio; Moreno San Pedro, Emilio; Cadena, José
      "El objetivo del presente estudio es determinar la calidad de vida en personas con diagnóstico de artritis reumatoide en una muestra de pacientes colombianos. Se evaluaron 124 participantes (110 mujeres y 14 hombres) con ...
       Artículo. 2005
    • Association between Secondary and Primary Sjögren's Syndrome in a Large Collection of Lupus Families 

      Aggarwal, Rachna; Anaya, Juan-Manuel; Koelsch, Kristi A.; Kurien, Biji T.; Scofield, R. Hal
      Systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS) share clinical and immunogenetic features and may occur together. We undertook this study to determine the risk of primary SS among SLE-unaffected relatives ...
       Artículo. 2015
    • Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility 

      Zhao, Jian; Wu, Hui; Khosravi, Melanie; Cui, Huijuan; Qian, Xiaoxia; Kelly, Jennifer A.; Kaufman, Kenneth M.; Langefeld, Carl D.; Williams, Adrienne H.; Comeau, Mary; Ziegler, Julie T.; Marion, Miranda C.; Adler, Adam; Glenn, Stuart B.; Alarcón-Riquelme, Marta E.; Pons-Estel, Bernardo A.; Harley, John B.; Bae, Sang-Cheol; Bang, So-Young; Cho, Soo-Kyung; Jacob, Chaim O.; Vyse, Timothy J.; Niewold, Timothy B.; Gaffney, Patrick M.; Moser, Kathy L.; Kimberly, Robert P.; Edberg, Jeffrey C.; Brown, Elizabeth E.; Alarcón, Graciela S.; Petri, Michelle A.; Ramsey-Goldman, Rosalind; Vilá, Luis M.; Reveille, John D.; James, Judith A.; Gilkeson, Gary S.; Kamen, Diane L.; Freedman, Barry I.; Anaya, Juan-Manuel; Merrill, Joan T.; Criswell, Lindsey A.; Scofield, Robert H.; Stevens, Anne M.; Guthridge, Joel M.; Chang, Deh-Ming; Song, Yeong Wook; Park, Ji Ah; Young Lee, Eun; Boackle, Susan; Grossman, Jennifer M.; Hahn, Bevra H.; Goodship, Timothy H. J.; Cantor, Rita M.; Yu, Chack-Yung; Shen, Nan; Tsao, Betty P.
      Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins ...
       Artículo. 2011
    • Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus 

      Adrianto, Indra; Wang, Shaofeng; Wiley, Graham B.; Lessard, Christopher J.; Kelly, Jennifer A.; Adler, Adam J.; Glenn, Stuart B.; Williams, Adrienne H.; Ziegler, Julie T.; Comeau, Mary E.; Marion, Miranda C.; Wakeland, Benjamin E.; Liang, Chaoying; Kaufman, Kenneth M.; Guthridge, Joel M.; Alarcón?Riquelme, Marta E.; Alarcón, Graciela S.; Anaya, Juan-Manuel; Bae, Sang?Cheol; Kim, Jae?Hoon; Bin Joo, Young; Boackle, Susan A.; Brown, Elizabeth E.; Petri, Michelle; Ramsey?Goldman, Rosalind; Reveille, John D.; Vilá, Luis M.; Criswell, Lindsey A.; Edberg, Jeffrey C.; Freedman, Barry I.; Gilkeson, Gary S.; Jacob, Chaim O.; James, Judith A.; Kamen, Diane L.; Kimberly, Robert P.; Martín, Javier; Merrill, Joan T.; Niewold, Timothy B.; Pons?Estel, Bernardo A.; Scofield, R. Hal; Stevens, Anne M.; Tsao, Betty P.; Vyse, Timothy J.; Langefeld, Carl D.; Harley, John B.; Wakeland, Edward K.; Moser, Kathy L.; Montgomery, Courtney G.; Gaffney, Patrick M.
      "Objective Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody production and altered type I interferon expression. Genetic surveys and genome-wide association studies have identified ...
       Artículo. 2012
    • Autoclinimetría : no más esperas para el paciente con artritis reumatoide . ¡Autoexamínese! 

      Anaya, Juan-Manuel; Rojas-Villarraga, Adriana; Mantilla, Rubén D.; Amaya-Amaya, Jenny
      La artritis reumatoide es la enfermedad inflamatoria y crónica más frecuente. Afecta más a las mujeres que a los hombres. Luego del diagnóstico, el paciente debe ser sometido a un proceso de seguimiento, que incluye un ...
       Documento de trabajo. 2012
    • Autoclinimetría aplicada colectivamente en pacientes Latinoamericanos con Artritis Reumatoide 

      Botello Corzo, Diana; Calderón, Rolando; Cruz-Tapias, Paola; Amaya-Amaya, Jenny; Calixto, Omar; Dominguez, Aura María; Mantilla, Rubén D.; Anaya, Juan-Manuel
      Para aplicar esquemas terapéuticos como la terapia de control estrecho en pacientes con Artritis Reumatoide (AR), Es necesario contar con mediciones objetivas de la actividad de la enfermedad. Para esto se han creado las ...
       Trabajo de grado. 2012
    • Autoimmune (auto-inflammatory) syndrome induced by adjuvants (ASIA)--animal models as a proof of concept 

      Cruz Tapias, Paola; Agmon Levin, Nancy; Israeli, Eitan; Anaya, Juan-Manuel; Shoenfeld, Yehuda
      ASIA syndrome, “Autoimmune (Auto-inflammatory) Syndromes Induced by Adjuvants” includes at least four conditions which share a similar complex of signs and symptoms and have been defined by hyperactive immune responses: ...
       Artículo. 2013
    • Autoimmune hepatitis - learning about your patients from their autoantibody profiles 

      Anaya, Juan-Manuel
      Autoimmune hepatitis (AIH) remains a disease without a diagnostic marker, and one that is as much an art to manage as is scientific discipline. As a broadly presenting clinical entity, AIH is a chronic and relapsing disease ...
       Artículo. 2011
    • Autoimmune neurological conditions associated with zika virus infection 

      Acosta-Ampudia, Yeny; Monsalve, Diana M.; Castillo-Medina, Luis F.; Rodríguez, Yhojan; Pacheco Nieva, Yovana; Halstead, Susan; Willison, Hugh J.; Anaya, Juan-Manuel; Ramirez-Santana, Carolina
      Zika virus (ZIKV) is an emerging flavivirus rapidly spreading throughout the tropical Americas. Aedes mosquitoes is the principal way of transmission of the virus to humans. ZIKV can be spread by transplacental, perinatal, ...
       Revisión. 2018
    • Autoimmune rheumatic diseases 

      Anaya, Juan-Manuel; Shoenfeld, Yehuda; Buttgereit, Frank; Gonzalez-Gay, Miguel
      "The term autoimmune rheumatic diseases (ARDs) encompasses a heterogeneous group of conditions characterized by joint involvement along with a wide spectrum of systemic manifestations. The most common ARDs are rheumatoid ...
       Editorial. 2014
    • Autoimmunity and tuberculosis. Opposite association with TNF polymorphism. 

      Anaya, Juan-Manuel; Correa, Paula A.; Gomez, Luis M.; Cadena, Jose
      Objective. To examine the influence of the –308 and –238 single nucleotide polymorphisms (SNP) of tumor necrosis factor-? gene (TNF) on patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), primary ...
       Artículo. 2005
    • Bases moleculares de la familia de la interleuquina-1 

      Velez Castrillon, Susana; Camargo, Jose F.; Correa, Paula A.; Anaya, Juan-Manuel
      La interleuquina-1 (IL-1) es un miembro importante del grupo de las citoquinas pro inflamatorias. Pertenece a una superfamilia de citoquinas relacionadas que lleva su nombre, de las cuales se conocen tres agonistas (IL-1?, ...
       Artículo. 2004