Now showing items 1-20 of 36

    • 16/6-idiotype expressing antibodies induce brain inflammation and cognitive impairment in mice: the mosaic of central nervous system involvement in lupus 

      Shaye, Kivity; Katzav, Aviva; Arango, María-Teresa; Landau-Rabi, Moran; Zafrir, Yaron; Agmon-Levin, Nancy; Blank, Miri; Anaya, Juan-Manuel; Mozes, Edna; Chapman, Joab; Shoenfeld, Yehuda
      Background: The 16/6-idiotype (16/6-Id) of the human anti-DNA antibody was found to induce experimental lupus in naive mice, manifested by production of autoantibodies, leukopenia and elevated inflammatory markers, as well ...
       Artículo. 2013
    • A comprehensive analysis and immunobiology of autoimmune neurological syndromes during the Zika virus outbreak in Cúcuta, Colombia 

      Anaya, Juan-Manuel; Rodríguez, Yhojan; Monsalve-Carmona, Diana; Vega, Daniel; Ojeda, Ernesto; Gonzalez-Bravo, Diana; Rodríguez-Jímenez, Mónica; Pinto-Díaz, Carlos A.; Chaparro, Pablo; Gunturiz, María L.; Ansari, Aftab A.; Gershwin, M. Eric; Molano-González, Nicolás; Ramirez-Santana, Carolina; Acosta-Ampudia, Yeny
      We have focused on the epidemiology and immunobiology of Zika virus (ZIKV) infection and factors associated with the development of Guillain-Barré syndrome (GBS) and other neurological syndromes in Cúcuta, the capital of ...
       Artículo. 2017
    • Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility 

      Zhao, Jian; Wu, Hui; Khosravi, Melanie; Cui, Huijuan; Qian, Xiaoxia; Kelly, Jennifer A.; Kaufman, Kenneth M.; Langefeld, Carl D.; Williams, Adrienne H.; Comeau, Mary; Ziegler, Julie T.; Marion, Miranda C.; Adler, Adam; Glenn, Stuart B.; Alarcón-Riquelme, Marta E.; Pons-Estel, Bernardo A.; Harley, John B.; Bae, Sang-Cheol; Bang, So-Young; Cho, Soo-Kyung; Jacob, Chaim O.; Vyse, Timothy J.; Niewold, Timothy B.; Gaffney, Patrick M.; Moser, Kathy L.; Kimberly, Robert P.; Edberg, Jeffrey C.; Brown, Elizabeth E.; Alarcón, Graciela S.; Petri, Michelle A.; Ramsey-Goldman, Rosalind; Vilá, Luis M.; Reveille, John D.; James, Judith A.; Gilkeson, Gary S.; Kamen, Diane L.; Freedman, Barry I.; Anaya, Juan-Manuel; Merrill, Joan T.; Criswell, Lindsey A.; Scofield, Robert H.; Stevens, Anne M.; Guthridge, Joel M.; Chang, Deh-Ming; Song, Yeong Wook; Park, Ji Ah; Young Lee, Eun; Boackle, Susan; Grossman, Jennifer M.; Hahn, Bevra H.; Goodship, Timothy H. J.; Cantor, Rita M.; Yu, Chack-Yung; Shen, Nan; Tsao, Betty P.
      Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins ...
       Artículo. 2011
    • Autoclinimetría : no más esperas para el paciente con artritis reumatoide . ¡Autoexamínese! 

      Anaya, Juan-Manuel; Rojas-Villarraga, Adriana; Mantilla, Rubén D.; Amaya-Amaya, Jenny-Carolina
      La artritis reumatoide es la enfermedad inflamatoria y crónica más frecuente. Afecta más a las mujeres que a los hombres. Luego del diagnóstico, el paciente debe ser sometido a un proceso de seguimiento, que incluye un ...
       Documento de trabajo. 2012
    • Autoclinimetría aplicada colectivamente en pacientes Latinoamericanos con Artritis Reumatoide 

      Botello Corzo, Diana; Calderón, Rolando; Cruz-Tapias, Paola; Amaya-Amaya, Jenny-Carolina; Calixto, Omar; Dominguez, Aura María; Mantilla, Rubén D.; Anaya, Juan-Manuel
      Para aplicar esquemas terapéuticos como la terapia de control estrecho en pacientes con Artritis Reumatoide (AR), Es necesario contar con mediciones objetivas de la actividad de la enfermedad. Para esto se han creado las ...
       Trabajo de grado. 2012
    • Autoimmune neurological conditions associated with zika virus infection 

      Acosta-Ampudia, Yeny; Monsalve, Diana M.; Castillo-Medina, Luis F.; Rodríguez, Yhojan; Pacheco Nieva, Yovana; Halstead, Susan; Willison, Hugh J.; Anaya, Juan-Manuel; Ramirez-Santana, Carolina
      Zika virus (ZIKV) is an emerging flavivirus rapidly spreading throughout the tropical Americas. Aedes mosquitoes is the principal way of transmission of the virus to humans. ZIKV can be spread by transplacental, perinatal, ...
       Revisión. 2018
    • Cardiovascular disease in latin american patients with systemic lupus erythematosus: a cross-sectional study and a systematic review 

      Amaya-Amaya, Jenny-Carolina; Sarmiento Monroy, Juan Camilo; Caro-Moreno, Julián; Molano-González, Nicolas; Mantilla, Rubén D.; Rojas-Villarraga, Adriana; Anaya, Juan-Manuel
      Objective. This study was performed to determine the prevalence of and associated risk factors for cardiovascular disease (CVD) in Latin American (LA) patients with systemic lupus erythematosus (SLE). Methods. First, a ...
       Artículo. 2013
    • Enfermedad tiroidea autoinmune en pacientes colombianos con lupus eritematoso sistémico 

      Franco Aristizabal, Juan Sebastian; Amaya-Amaya, Jenny-Carolina; Molano-González, Nicolas; Rodríguez-Jímenez, Mónica; Acosta-Ampudia, Yeny; Anaya, Juan-Manuel
      Objetivos: Determinar la prevalencia y los factores asociados con el desarrollo de hipotiroidismo autoinmune (HA) en una cohorte de pacientes con lupus eritematoso sistémico (LES), y analizar la información actual en cuanto ...
       Trabajo de grado. 2015
    • Espondiloartropatias seronegativas y viceversa 

      Perez-Fernandez, Oscar-Mauricio; Mantilla, Rubén D.; Anaya, Juan-Manuel
      Introducción. Las Espondiloartropatias Seronegativas (EAS) son un grupo de enfermedades interrelacionadas que presentan compromiso inflamatorio articular y hallazgos extraarticulares. Por otra parte, las Enfermedades ...
       Trabajo de grado. 2011
    • Genetic basis of Sjögren's syndrome. How strong is the evidence? 

      Anaya, Juan-Manuel; Delgado Vega, Angélica María; Castiblanco, John
      Sjögren's syndrome (SS) is a late-onset chronic autoimmune disease (AID) affecting the exocrine glands, mainly the salivary and lachrymal. Genetic studies on twins with primary SS have not been performed, and only a few ...
       Artículo. 2006
    • Hallazgos radiológicos de la enfermedad pulmonar en pacientes Colombianos con esclerodermia 

      Morales, Adriana; Pérez, Camila; Molano-González, Nicolas; Rojas-Villarraga, Adriana; Carrillo Bayona, Jorge Alberto; Anaya, Juan-Manuel
      La esclerosis sistémica (ES) es una enfermedad autoinmune multisistémica que afecta principalmente la piel, los pulmones, el tracto gastrointestinal, el corazón y los riñones. La enfermedad pulmonar, presente en casi el ...
       Trabajo de grado. 2015
    • How do autoimmune diseases cluster in families? A systematic review and meta-analysis 

      Cardenas Roldan, Jorge; Rojas-Villarraga, Adriana; Anaya, Juan-Manuel
      Background: A primary characteristic of complex genetic diseases is that affected individuals tend to cluster in families (that is, familial aggregation). Aggregation of the same autoimmune condition, also referred to as ...
       Artículo. 2013
    • Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons 

      Li, He; Reksten, Tove Ragna; Ice, John A.; Kelly, Jennifer A.; Adrianto, Indra; Rasmussen, Astrid; Wang, Shaofeng; He, Bo; Grundahl, Kiely M.; Glenn, Stuart B.; Miceli-Richard, Corinne; Bowman, Simon; Lester, Sue; Eriksson, Per; Eloranta, Maija-Leena; Brun, Johan G.; Gøransson, Lasse G.; Harboe, Erna; Guthridge, Joel M.; Kaufman, Kenneth M.; Kvarnström, Marika; Cunninghame Graham, Deborah S.; Patel, Ketan; Adler, Adam J.; Farris, A. Darise; Brennan, Michael T.; Chodosh, James; Gopalakrishnan, Rajaram; Weisman, Michael H.; Venuturupalli, Swamy; Wallace, Daniel J.; Hefner, Kimberly S.; Houston, Glen D.; Huang, Andrew J. W.; Hughes, Pamela J.; Lewis, David M.; Radfar, Lida; Vista, Evan S.; Contessa E., Edgar; Rohrer, Michael D.; Stone, Donald U.; Vyse, Timothy J.; Harley, John B.; Gaffney, Patrick M.; James, Judith A.; Turner, Sean; Alevizos, Ilias; Anaya, Juan-Manuel; Rhodus, Nelson L.; Segal, Barbara M.; Montgomery, Courtney G.; Scofield, R. Hal; Kovats, Susan; Mariette, Xavier; Rönnblom, Lars; Witte, Torsten; Rischmueller, Maureen; Wahren-Herlenius, Marie; Omdal, Roald; Jonsson, Roland; Ng, Wan-Fai; Nordmark, Gunnel; Lessard, Christopher J.; Sivils, Kathy L.
      Sjögren’s syndrome (SS) is a common, autoimmune exocrinopathy distinguished by keratoconjunctivitis sicca and xerostomia. Patients frequently develop serious complications including lymphoma, pulmonary dysfunction, neuropathy, ...
       Artículo. 2017
    • Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study 

      Lessard, Christopher J.; Adrianto, Indra; Kelly, Jennifer A.; Kaufman, Kenneth M.; Grundahl, Kiely M.; Adler, Adam; Williams, Adrienne H.; Gallant, Caroline J.; Alarcón-Riquelme, Marta E.; Anaya, Juan-Manuel; Bae, Sang-Cheol; Boackle, Susan; Brown, Elizabeth E.; Chang, Deh-Ming; Criswel, Lindsey A.; Edberg, Jeffrey C.; Freedman, Barry I.; Gregersen, Peter K.; Gilkeson, Gary S.; Jacob, Chaim O.; James, Judith A.; Kamen, Diane L.; Kimberly, Robert P.; Martin, Javier; Merrill, Joan T.; Niewold, Timothy B.; Park, So-Yeon; Petri, Michelle A.; Pons-Estel, Bernardo A.; Ramsey-Goldman, Rosalind; Reveille, John D.; Song, Yeong Wook; Stevens, Anne M.; Tsao, Betty P.; Vila, Luis M.; Vyse, Timothy J.; Yu, Chack-Yung; Guthridge, Joel M.; Bruner, Gail R.; Langefeld, Carl D.; Montgomery, Courtney; Harley, John B.; Scofield, Robert H.; Gaffney, Patrick M.; Moser, Kathy L.
      Systemic lupus erythematosus (SLE) is considered to be the prototypic autoimmune disease, with a complex genetic architecture influenced by environmental factors. We sought to replicate a putative association at 11p13 not ...
       Artículo. 2011
    • Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study 

      Lessard, Christopher J.; Adrianto, Indra; Ice, John A.; Wiley, Graham B.; Kelly, Jennifer A.; Glenn, Stuart B.; Adler, Adam J.; Li, He; Rasmussen, Astrid; Williams, Adrienne H.; Ziegler, Julie; Comeau, Mary; Marion, Miranda; Wakeland, Benjamin E.; Liang, Chaoying; Ramos, Paula S.; Grundahl, Kiely M.; Gallant, Caroline J.; Alarcón-Riquelme, Marta E.; Alarcón, Graciela S.; Anaya, Juan-Manuel; Bae, Sang-Cheol; Boackle, Susan; Brown, Elizabeth E.; Chang, Deh-Ming; Cho, Soo-Kyung; Criswel, Lindsey A.; Edberg, Jeffrey C.; Freedman, Barry I.; Gilkeson, Gary S.; Jacob, Chaim O.; James, Judith A.; Kamen, Diane L.; Kimberly, Robert P.; Kim, Jae-Hoon; Martin, Javier; Merrill, Joan T.; Niewold, Timothy B.; Park, So-Yeon; Petri, Michelle A.; Pons-Estel, Bernardo A.; Ramsey-Goldman, Rosalind; Reveille, John D.; Scofield, Robert H.; Song, Yeong Wook; Stevens, Anne M.; Tsao, Betty P.; Vila, Luis M.; Vyse, Timothy J.; Yu, Chack-Yung; Guthridge, Joel M.; Kaufman, Kenneth M.; Harley, John B.; Wakeland, Edward K.; Langefeld, Carl D.; Gaffney, Patrick M.; Montgomery, Courtney G.; Moser, Kathy L.
      Systemic lupus erythematosus (SLE) is a chronic heterogeneous autoimmune disorder characterized by the loss of tolerance to self-antigens and dysregulated interferon responses. The etiology of SLE is complex, involving ...
       Artículo. 2012
    • Introducing polyautoimmunity: secondary autoimmune diseases no longer exist 

      Rojas-Villarraga, Adriana; Amaya-Amaya, Jenny-Carolina; Rodriguez-Rodriguez, Alberto; Mantilla, Rubén D.; Anaya, Juan-Manuel
      Similar pathophysiological mechanisms within autoimmune diseases have stimulated searches for common genetic roots. Polyautoimmunity is defined as the presence of more than one autoimmune disease in a single patient. When ...
       Artículo. 2012
    • Is there a common genetic basis for autoimmune diseases? 

      Anaya, Juan-Manuel; Gómez, Luis Miguel; Castiblanco, John
      Autoimmune diseases (ADs) represent a diverse collection of diseases in terms of their demographic profile and primary clinical manifestations. The commonality between them however, is the damage to tissues and organs that ...
       Artículo. 2006
    • Medicina personalizada: La salud y la enfermedad sí se pueden predecir 

      Anaya, Juan-Manuel; Sarmiento, Juan Camilo; Montoya Ortiz, Gladys; Molano-González, Nicolas; Pérez Cristiano, Janeth; Rojas-Villarraga, Adriana
      Años y años de constante investigación en busca del entendimiento y el tratamiento de las distintas enfermedades, han llevado a la conclusión de que la medicina debe ser tratada de manera individual, pues cada paciente es, ...
       Documento de trabajo. 2013
    • MicroRNA-3148 Modulates Allelic Expression of Toll-Like Receptor 7 Variant Associated with Systemic Lupus Erythematosus 

      Deng, Yun; Zhao, Jian; Sakurai, Daisuke; Kaufman, Kenneth M.; Edberg, Jeffrey C.; Kimberly, Robert P.; Kamen, Diane L.; Gilkeson, Gary S.; Jacob, Chaim O.; Scofield, Robert H.; Langefeld, Carl D.; Kelly, Jennifer A.; Ramsey-Goldman, Rosalind; Petri, Michelle A.; Reveille, John D.; Vilá, Luis M.; Alarcón, Graciela S.; Vyse, Timothy J.; Pons-Estel, Bernardo A.; Freedman, Barry I.; Gaffney, Patrick M.; Moser Sivils, Kathy; James, Judith A.; Gregersen, Peter K.; Anaya, Juan-Manuel; Niewold, Timothy B.; Merrill, Joan T.; Criswell, Lindsey A.; Stevens, Anne M.; Boackle, Susan; Cantor, Rita M.; Chen, Weiling; Grossman, Jenniffer M.; Hahn, Bevra H.; Harley, John B.; Alarcón-Riquelme, Marta E.; Brown, Elizabeth E.; Tsao, Betty P.
      We previously reported that the G allele of rs3853839 at 3′untranslated region (UTR) of Toll-like receptor 7 (TLR7) was associated with elevated transcript expression and increased risk for systemic lupus erythematosus ...
       Artículo. 2013
    • Nerve conduction patterns in Guillain-Barré syndrome associated with zika virus infection in Cucuta, Colombia 

      González-Bravo, Diana; Uncini, Antonino; Ojeda, Ernesto C.; Rodríguez, Yhojan; Monsalve, Diana M.; Vega, Daniel; Paipilla, Deyanira; Torres, Leidy; Osorio, Jorge E.; Anaya, Juan-Manuel; Acosta-Ampudia, Yeny; Ramirez-Santana, Carolina; Molano-González, Nicolas
      Background: Zika virus (ZIKV) infection has been associated with an increased incidence of Guillain-Barré syndrome (GBS) but the relative frequency of acute inflammatory demyelinating polyradiculoneuropathy (AIDP) and ...
       Trabajo de grado. 2018

       

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