Now showing items 1-20 of 129

    • 16/6-idiotype expressing antibodies induce brain inflammation and cognitive impairment in mice: the mosaic of central nervous system involvement in lupus 

      Shaye, Kivity; Katzav, Aviva; Arango, María-Teresa; Landau-Rabi, Moran; Zafrir, Yaron; Agmon-Levin, Nancy; Blank, Miri; Anaya, Juan-Manuel; Mozes, Edna; Chapman, Joab; Shoenfeld, Yehuda
      Background: The 16/6-idiotype (16/6-Id) of the human anti-DNA antibody was found to induce experimental lupus in naive mice, manifested by production of autoantibodies, leukopenia and elevated inflammatory markers, as well ...
       Artículo. 2013
    • A comprehensive analysis and immunobiology of autoimmune neurological syndromes during the Zika virus outbreak in Cúcuta, Colombia 

      Anaya, Juan-Manuel; Rodríguez, Yhojan; Monsalve-Carmona, Diana; Vega, Daniel; Ojeda, Ernesto; Gonzalez-Bravo, Diana; Rodríguez-Jímenez, Mónica; Pinto-Díaz, Carlos A.; Chaparro, Pablo; Gunturiz, María L.; Ansari, Aftab A.; Gershwin, M. Eric; Molano-González, Nicolás; Ramirez-Santana, Carolina; Acosta-Ampudia, Yeny
      We have focused on the epidemiology and immunobiology of Zika virus (ZIKV) infection and factors associated with the development of Guillain-Barré syndrome (GBS) and other neurological syndromes in Cúcuta, the capital of ...
       Artículo. 2017
    • A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus 

      "Patel, Zubin H; Lu, Xiaoming; Miller, Daniel; Forney, Carmy R; Lee, Joshua; Lynch, Arthur; Schroeder, Connor; Parks, Lois; Magnusen, Albert F; Chen, Xiaoting; Pujato, Mario; Maddox, Avery; Zoller, Erin E; Namjou, Bahram; Brunner, Hermine I; Henrickson, Michael; Huggins, Jennifer L; Williams, Adrienne H; Ziegler, Julie T; Comeau, Mary E; Marion, Miranda C; Glenn, Stuart B; Adler, Adam; Shen, Nan; Nath, Swapan K; Stevens, Anne M; Freedman, Barry I; Pons-Estel, Bernardo A; Tsao, Betty P; Jacob, Chaim O; Kamen, Diane L; Brown, Elizabeth E; Gilkeson, Gary S; Alarcón, Graciela S; Martin, Javier; Reveille, John D; Anaya, Juan-Manuel; James, Judith A; Sivils, Kathy L; Criswell, Lindsey A; Vilá, Luis M; Petri, Michelle; Scofield, R Hal; Kimberly, Robert P; Edberg, Jeffrey C; Ramsey-Goldman, Rosalind; Bang, So-Young; Lee, Hye-Soon; Bae, Sang-Cheol; Boackle, Susan A; Graham, Deborah Cunninghame; Vyse, Timothy J; Merrill, Joan T; Niewold, Timothy B; Ainsworth, Hannah C; Silverman, Earl D; Weisman, Michael H; Wallace, Daniel J; Raj, Prithvi; Guthridge, Joel M; Gaffney, Patrick M; Kelly, Jennifer A; Alarcón-Riquelme, Marta E; Langefeld, Carl D; Wakeland, Edward K; Kaufman, Kenneth M; Weirauch, Matthew T; Harley, John B; Kottyan, Leah C"
      "Systemic lupus erythematosus (SLE or lupus) (OMIM: 152700) is a chronic autoimmune disease with debilitating inflammation that affects multiple organ systems. The STAT1-STAT4 locus is one of the first and most highly ...
       Artículo. 2018
    • A polymorphism in the inducible nitric oxide synthase gene is associated with tuberculosis 

      "Gómez, Luis Miguel; Anaya, Juan-Manuel; Vilchez, José Ramón; Cadena, Jose; Hinojosa, Rosa; Vélez, Luciano; Lopez-Nevot, Miguel Angel; Martín, Javier"
      "iNOS or NOS2 is a molecule that plays a key role in the immunological control of a broad spectrum of infectious agents. Investigation is hampered by difficulty in estimating in vivo production of nitric oxide (NO), but ...
       Artículo. 2007
    • ABIN1 dysfunction as a genetic basis for lupus nephritis 

      "Caster, Dawn J.; Korte, Erik A.; Nanda, Sambit K.; McLeish, Kenneth R.; Oliver, Rebecca K.; G'Sell, Rachel T.; Sheehan, Ryan M.; Freeman, Darrell W.; Coventry, Susan C.; Kelly, Jennifer A.; Guthridge, Joel M.; James, Judith A.; Sivils, Kathy L.; Alarcon-Riquelme, Marta E.; Scofield, R. Hal; Adrianto, Indra; Gaffney, Patrick M.; Stevens, Anne M.; Freedman, Barry I.; Langefeld, Carl D.; Tsao, Betty P.; Pons-Estel, Bernardo A.; Jacob, Chaim O.; Kamen, Diane L.; Gilkeson, Gary S.; Brown, Elizabeth E.; Alarcon, Graciela S.; Edberg, Jeffrey C.; Kimberly, Robert P.; Martin, Javier; Merrill, Joan T.; Harley, John B.; Kaufman, Kenneth M.; Reveille, John D.; Anaya, Juan-Manuel; Criswell, Lindsey A.; Vila, Luis M.; Petri, Michelle; Ramsey-Goldman, Rosalind; Bae, Sang-Cheol; Boackle, Susan A.; Vyse, Timothy J.; Niewold, Timothy B.; Cohen, Philip; Powell, David W."
      "The genetic factors underlying the pathogenesis of lupus nephritis associated with systemic lupus erythematosus are largely unknown, although animal studies indicate that nuclear factor (NF)-?B is involved. We reported ...
       Artículo. 2013
    • Anti-alpha-actinin antibodies are part of the anti-cell membrane antibody spectrum that characterize patients with lupus nephritis 

      Seret, Guillaume; Cañas, Felipe; Costanzo, Laurence Pougnet-Di; Hanrotel-Saliou, Catherine; Jousse-Joulin, Sandrine; Le Meur, Yannick; Saraux, Alain; Valeri, Antoine; Putterman, Chaim; Youinou, Pierre; Rojas-Villarraga, Adriana; Anaya, Juan-Manuel; Renaudineau, Yves
      Anti-membrane autoantibodies (MbA) have been reported in sera from patients with lupus nephritis (LN) but the targets of the MbA remain to be explored, which is the aim of the current study. Sera were collected from 40 ...
       Artículo. 2015
    • Antinuclear autoantibodies: Discordance among four different assays 

      Pacheco, Yovana; Monsalve, Diana M; Acosta-Ampudia, Yeny; Rojas, Cilia; Anaya, Juan-Manuel; Ramírez-Santana, Carolina
      Detection of antinuclear antibodies (ANAs) is of paramount importance for diagnosis and assessment of autoimmune diseases (ADs), but may vary depending on the method used. Therefore, we aimed to compare three different ...
       Documento de conferencia. 2020
    • Artritis reumatoide: Bases moleculares clinicas y terapéuticas 

      Anaya, Juan-Manuel; Pineda-Tamayo, Ricardo; Gomez, Luis Miguel; Galarza Maldonado, Claudio; Rojas-Villarraga, Adriana; Martin, Javeir
      Después de rastrear los principios de la artritis reumatoide tan enigmática tanto en su inicio como en su patogénesis se ve cómo poco a poco se gestaron y organizaron una serie de hechos clínicos, de laboratorio y de ...
       Libro. 2006
    • Asociación no-HLA con Enfermedades Autoinmunes 

      Serrano, Norma C.; Páez, Carolina; Millán, Paula; Anaya, Juan-Manuel
      El patrón de herencia de las enfermedades autoinmunes (EAI) es complejo, indicando que múltiples genes se encuentran involucrados en su etiología. A pesar que genes del complejo mayor de histocompatibilidad, ubicado en ...
       parte de Libro. 2005
    • Association between Secondary and Primary Sjögren's Syndrome in a Large Collection of Lupus Families 

      Aggarwal, Rachna; Anaya, Juan-Manuel; Koelsch, Kristi A.; Kurien, Biji T.; Scofield, R. Hal
      Systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS) share clinical and immunogenetic features and may occur together. We undertook this study to determine the risk of primary SS among SLE-unaffected relatives ...
       Artículo. 2015
    • Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility 

      Zhao, Jian; Wu, Hui; Khosravi, Melanie; Cui, Huijuan; Qian, Xiaoxia; Kelly, Jennifer A.; Kaufman, Kenneth M.; Langefeld, Carl D.; Williams, Adrienne H.; Comeau, Mary; Ziegler, Julie T.; Marion, Miranda C.; Adler, Adam; Glenn, Stuart B.; Alarcón-Riquelme, Marta E.; Pons-Estel, Bernardo A.; Harley, John B.; Bae, Sang-Cheol; Bang, So-Young; Cho, Soo-Kyung; Jacob, Chaim O.; Vyse, Timothy J.; Niewold, Timothy B.; Gaffney, Patrick M.; Moser, Kathy L.; Kimberly, Robert P.; Edberg, Jeffrey C.; Brown, Elizabeth E.; Alarcón, Graciela S.; Petri, Michelle A.; Ramsey-Goldman, Rosalind; Vilá, Luis M.; Reveille, John D.; James, Judith A.; Gilkeson, Gary S.; Kamen, Diane L.; Freedman, Barry I.; Anaya, Juan-Manuel; Merrill, Joan T.; Criswell, Lindsey A.; Scofield, Robert H.; Stevens, Anne M.; Guthridge, Joel M.; Chang, Deh-Ming; Song, Yeong Wook; Park, Ji Ah; Young Lee, Eun; Boackle, Susan; Grossman, Jennifer M.; Hahn, Bevra H.; Goodship, Timothy H. J.; Cantor, Rita M.; Yu, Chack-Yung; Shen, Nan; Tsao, Betty P.
      Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins ...
       Artículo. 2011
    • Autoclinimetría : no más esperas para el paciente con artritis reumatoide . ¡Autoexamínese! 

      Anaya, Juan-Manuel; Rojas-Villarraga, Adriana; Mantilla, Rubén D.; Amaya-Amaya, Jenny-Carolina
      La artritis reumatoide es la enfermedad inflamatoria y crónica más frecuente. Afecta más a las mujeres que a los hombres. Luego del diagnóstico, el paciente debe ser sometido a un proceso de seguimiento, que incluye un ...
       Documento de trabajo. 2012
    • Autoclinimetría aplicada colectivamente en pacientes Latinoamericanos con Artritis Reumatoide 

      Botello Corzo, Diana; Calderón, Rolando; Cruz-Tapias, Paola; Amaya-Amaya, Jenny-Carolina; Calixto, Omar; Dominguez, Aura María; Mantilla, Rubén D.; Anaya, Juan-Manuel
      Para aplicar esquemas terapéuticos como la terapia de control estrecho en pacientes con Artritis Reumatoide (AR), Es necesario contar con mediciones objetivas de la actividad de la enfermedad. Para esto se han creado las ...
       Trabajo de grado. 2012
    • Autoimmune neurological conditions associated with zika virus infection 

      Acosta-Ampudia, Yeny; Monsalve, Diana M.; Castillo-Medina, Luis F.; Rodríguez, Yhojan; Pacheco Nieva, Yovana; Halstead, Susan; Willison, Hugh J.; Anaya, Juan-Manuel; Ramirez-Santana, Carolina
      Zika virus (ZIKV) is an emerging flavivirus rapidly spreading throughout the tropical Americas. Aedes mosquitoes is the principal way of transmission of the virus to humans. ZIKV can be spread by transplacental, perinatal, ...
       Revisión. 2018
    • Autoimmune rheumatic diseases 

      Anaya, Juan-Manuel; Shoenfeld, Yehuda; Buttgereit, Frank; Gonzalez-Gay, Miguel
      "The term autoimmune rheumatic diseases (ARDs) encompasses a heterogeneous group of conditions characterized by joint involvement along with a wide spectrum of systemic manifestations. The most common ARDs are rheumatoid ...
       Editorial. 2014
    • Autoimmune Thyroid Disease in Rheumatoid Arthritis: A Global Perspective 

      Roldán, Jorge Cárdenas; Amaya-Amaya, Jenny; la Hoz, Juan Castellanos-de; Giraldo-Villamil, Juliana; Montoya-Ortiz, Gladys; Cruz-Tapias, Paola; Rojas-Villarraga, Adriana; Mantilla, Rubén D.; Anaya, Juan-Manuel
      Objective. To determine the prevalence and impact of autoimmune thyroid disease (AITD) in patients with rheumatoid arthritis (RA). Methods. Eight-hundred patients were included. The association between AITD and RA was ...
       Artículo. 2012
    • Autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA) after quadrivalent human papillomavirus vaccination in Colombians: a call for personalised medicine 

      Anaya, Juan-Manuel; Reyes, Benjamin; Perdomo-Arciniegas, Ana M; Camacho-Rodríguez, Bernardo; Rojas-Villarraga, Adriana
      This was a case study in which 3 patients with autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA) after quadrivalent human papillomavirus vaccination (HPV) were evaluated and described. All the patients were ...
       Artículo. 2015
    • Autoimmunity and autoimmune disease: A Colombian construction beyond deconstructions 

      Anaya, Juan-Manuel
      The first Colombian Autoimmune Symposium held in Medellin, Colombia, February 23–25, 2005, covered the entire spectrum of the diverse aspects of autoimmunity and autoimmune disorders. The symposium originated as part of a ...
       Editorial. 2006
    • Autoinmunidad y enfermedad autoinmune 

      Anaya, Juan-Manuel; Shoenfeld, Yehuda; Correa, Paula A.; García-Carrasco, Mario; Cervera, Ricard
      Resulta altamente útil y oportuno este libro de Juan-Manuel Anaya, Yehuda Shoenfeld, Paula A. Correa, Mario García-Carrasco y Ricard Cervera. Tuvieron ellos el acierto de obtener la colaboración de varios de los mejores ...
       Libro. 2005
    • Can appropriate systemic treatment help protect the cornea in patients with rheumatoid arthritis? A multidisciplinary approach to autoimmune ocular involvement 

      "Amador-Patarroyo, Manuel J; Jalil-Florencia, Emilio; Otero-Marquez, Oscar; Molano-Gonzalez, Nicolás; Mantilla, Ruben D; Rojas-Villarraga, Adriana; Anaya, Juan-Manuel; Barraquer-Coll, Carmen"
      "Purpose: To correlate rheumatologic with ophthalmic and laboratory findings in patients with rheumatoid arthritis (RA) to identify what effect these have on development of ocular disease. Methods: This is a cross-sectional ...
       Artículo. 2018

       

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