Now showing items 1-20 of 83

    • 16/6-idiotype expressing antibodies induce brain inflammation and cognitive impairment in mice: the mosaic of central nervous system involvement in lupus 

      Shaye, Kivity; Katzav, Aviva; Arango, María-Teresa; Landau-Rabi, Moran; Zafrir, Yaron; Agmon-Levin, Nancy; Blank, Miri; Anaya, Juan-Manuel; Mozes, Edna; Chapman, Joab; Shoenfeld, Yehuda
      Background: The 16/6-idiotype (16/6-Id) of the human anti-DNA antibody was found to induce experimental lupus in naive mice, manifested by production of autoantibodies, leukopenia and elevated inflammatory markers, as well ...
       Artículo. 2013
    • A comprehensive analysis and immunobiology of autoimmune neurological syndromes during the Zika virus outbreak in Cúcuta, Colombia 

      Anaya, Juan-Manuel; Rodríguez, Yhojan; Monsalve-Carmona, Diana; Vega, Daniel; Ojeda, Ernesto; Gonzalez-Bravo, Diana; Rodríguez-Jímenez, Mónica; Pinto-Díaz, Carlos A.; Chaparro, Pablo; Gunturiz, María L.; Ansari, Aftab A.; Gershwin, M. Eric; Molano-González, Nicolás; Ramirez-Santana, Carolina; Acosta-Ampudia, Yeny
      We have focused on the epidemiology and immunobiology of Zika virus (ZIKV) infection and factors associated with the development of Guillain-Barré syndrome (GBS) and other neurological syndromes in Cúcuta, the capital of ...
       Artículo. 2017
    • A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus 

      "Patel, Zubin H; Lu, Xiaoming; Miller, Daniel; Forney, Carmy R; Lee, Joshua; Lynch, Arthur; Schroeder, Connor; Parks, Lois; Magnusen, Albert F; Chen, Xiaoting; Pujato, Mario; Maddox, Avery; Zoller, Erin E; Namjou, Bahram; Brunner, Hermine I; Henrickson, Michael; Huggins, Jennifer L; Williams, Adrienne H; Ziegler, Julie T; Comeau, Mary E; Marion, Miranda C; Glenn, Stuart B; Adler, Adam; Shen, Nan; Nath, Swapan K; Stevens, Anne M; Freedman, Barry I; Pons-Estel, Bernardo A; Tsao, Betty P; Jacob, Chaim O; Kamen, Diane L; Brown, Elizabeth E; Gilkeson, Gary S; Alarcón, Graciela S; Martin, Javier; Reveille, John D; Anaya, Juan-Manuel; James, Judith A; Sivils, Kathy L; Criswell, Lindsey A; Vilá, Luis M; Petri, Michelle; Scofield, R Hal; Kimberly, Robert P; Edberg, Jeffrey C; Ramsey-Goldman, Rosalind; Bang, So-Young; Lee, Hye-Soon; Bae, Sang-Cheol; Boackle, Susan A; Graham, Deborah Cunninghame; Vyse, Timothy J; Merrill, Joan T; Niewold, Timothy B; Ainsworth, Hannah C; Silverman, Earl D; Weisman, Michael H; Wallace, Daniel J; Raj, Prithvi; Guthridge, Joel M; Gaffney, Patrick M; Kelly, Jennifer A; Alarcón-Riquelme, Marta E; Langefeld, Carl D; Wakeland, Edward K; Kaufman, Kenneth M; Weirauch, Matthew T; Harley, John B; Kottyan, Leah C"
      "Systemic lupus erythematosus (SLE or lupus) (OMIM: 152700) is a chronic autoimmune disease with debilitating inflammation that affects multiple organ systems. The STAT1-STAT4 locus is one of the first and most highly ...
       Artículo. 2018
    • A polymorphism in the inducible nitric oxide synthase gene is associated with tuberculosis 

      "Gómez, Luis Miguel; Anaya, Juan-Manuel; Vilchez, José Ramón; Cadena, Jose; Hinojosa, Rosa; Vélez, Luciano; Lopez-Nevot, Miguel Angel; Martín, Javier"
      "iNOS or NOS2 is a molecule that plays a key role in the immunological control of a broad spectrum of infectious agents. Investigation is hampered by difficulty in estimating in vivo production of nitric oxide (NO), but ...
       Artículo. 2007
    • ABIN1 dysfunction as a genetic basis for lupus nephritis 

      "Caster, Dawn J.; Korte, Erik A.; Nanda, Sambit K.; McLeish, Kenneth R.; Oliver, Rebecca K.; G'Sell, Rachel T.; Sheehan, Ryan M.; Freeman, Darrell W.; Coventry, Susan C.; Kelly, Jennifer A.; Guthridge, Joel M.; James, Judith A.; Sivils, Kathy L.; Alarcon-Riquelme, Marta E.; Scofield, R. Hal; Adrianto, Indra; Gaffney, Patrick M.; Stevens, Anne M.; Freedman, Barry I.; Langefeld, Carl D.; Tsao, Betty P.; Pons-Estel, Bernardo A.; Jacob, Chaim O.; Kamen, Diane L.; Gilkeson, Gary S.; Brown, Elizabeth E.; Alarcon, Graciela S.; Edberg, Jeffrey C.; Kimberly, Robert P.; Martin, Javier; Merrill, Joan T.; Harley, John B.; Kaufman, Kenneth M.; Reveille, John D.; Anaya, Juan-Manuel; Criswell, Lindsey A.; Vila, Luis M.; Petri, Michelle; Ramsey-Goldman, Rosalind; Bae, Sang-Cheol; Boackle, Susan A.; Vyse, Timothy J.; Niewold, Timothy B.; Cohen, Philip; Powell, David W."
      "The genetic factors underlying the pathogenesis of lupus nephritis associated with systemic lupus erythematosus are largely unknown, although animal studies indicate that nuclear factor (NF)-?B is involved. We reported ...
       Artículo. 2013
    • Association between Secondary and Primary Sjögren's Syndrome in a Large Collection of Lupus Families 

      Aggarwal, Rachna; Anaya, Juan-Manuel; Koelsch, Kristi A.; Kurien, Biji T.; Scofield, R. Hal
      Systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS) share clinical and immunogenetic features and may occur together. We undertook this study to determine the risk of primary SS among SLE-unaffected relatives ...
       Artículo. 2015
    • Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility 

      Zhao, Jian; Wu, Hui; Khosravi, Melanie; Cui, Huijuan; Qian, Xiaoxia; Kelly, Jennifer A.; Kaufman, Kenneth M.; Langefeld, Carl D.; Williams, Adrienne H.; Comeau, Mary; Ziegler, Julie T.; Marion, Miranda C.; Adler, Adam; Glenn, Stuart B.; Alarcón-Riquelme, Marta E.; Pons-Estel, Bernardo A.; Harley, John B.; Bae, Sang-Cheol; Bang, So-Young; Cho, Soo-Kyung; Jacob, Chaim O.; Vyse, Timothy J.; Niewold, Timothy B.; Gaffney, Patrick M.; Moser, Kathy L.; Kimberly, Robert P.; Edberg, Jeffrey C.; Brown, Elizabeth E.; Alarcón, Graciela S.; Petri, Michelle A.; Ramsey-Goldman, Rosalind; Vilá, Luis M.; Reveille, John D.; James, Judith A.; Gilkeson, Gary S.; Kamen, Diane L.; Freedman, Barry I.; Anaya, Juan-Manuel; Merrill, Joan T.; Criswell, Lindsey A.; Scofield, Robert H.; Stevens, Anne M.; Guthridge, Joel M.; Chang, Deh-Ming; Song, Yeong Wook; Park, Ji Ah; Young Lee, Eun; Boackle, Susan; Grossman, Jennifer M.; Hahn, Bevra H.; Goodship, Timothy H. J.; Cantor, Rita M.; Yu, Chack-Yung; Shen, Nan; Tsao, Betty P.
      Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins ...
       Artículo. 2011
    • Autoclinimetría : no más esperas para el paciente con artritis reumatoide . ¡Autoexamínese! 

      Anaya, Juan-Manuel; Rojas-Villarraga, Adriana; Mantilla, Rubén D.; Amaya-Amaya, Jenny-Carolina
      La artritis reumatoide es la enfermedad inflamatoria y crónica más frecuente. Afecta más a las mujeres que a los hombres. Luego del diagnóstico, el paciente debe ser sometido a un proceso de seguimiento, que incluye un ...
       Documento de trabajo. 2012
    • Autoclinimetría aplicada colectivamente en pacientes Latinoamericanos con Artritis Reumatoide 

      Botello Corzo, Diana; Calderón, Rolando; Cruz-Tapias, Paola; Amaya-Amaya, Jenny-Carolina; Calixto, Omar; Dominguez, Aura María; Mantilla, Rubén D.; Anaya, Juan-Manuel
      Para aplicar esquemas terapéuticos como la terapia de control estrecho en pacientes con Artritis Reumatoide (AR), Es necesario contar con mediciones objetivas de la actividad de la enfermedad. Para esto se han creado las ...
       Trabajo de grado. 2012
    • Autoimmune neurological conditions associated with zika virus infection 

      Acosta-Ampudia, Yeny; Monsalve, Diana M.; Castillo-Medina, Luis F.; Rodríguez, Yhojan; Pacheco Nieva, Yovana; Halstead, Susan; Willison, Hugh J.; Anaya, Juan-Manuel; Ramirez-Santana, Carolina
      Zika virus (ZIKV) is an emerging flavivirus rapidly spreading throughout the tropical Americas. Aedes mosquitoes is the principal way of transmission of the virus to humans. ZIKV can be spread by transplacental, perinatal, ...
       Revisión. 2018
    • Autoimmune rheumatic diseases 

      Anaya, Juan-Manuel; Shoenfeld, Yehuda; Buttgereit, Frank; Gonzalez-Gay, Miguel
      "The term autoimmune rheumatic diseases (ARDs) encompasses a heterogeneous group of conditions characterized by joint involvement along with a wide spectrum of systemic manifestations. The most common ARDs are rheumatoid ...
       Editorial. 2014
    • Can appropriate systemic treatment help protect the cornea in patients with rheumatoid arthritis? A multidisciplinary approach to autoimmune ocular involvement 

      "Amador-Patarroyo, Manuel J; Jalil-Florencia, Emilio; Otero-Marquez, Oscar; Molano-Gonzalez, Nicolás; Mantilla, Ruben D; Rojas-Villarraga, Adriana; Anaya, Juan-Manuel; Barraquer-Coll, Carmen"
      "Purpose: To correlate rheumatologic with ophthalmic and laboratory findings in patients with rheumatoid arthritis (RA) to identify what effect these have on development of ocular disease. Methods: This is a cross-sectional ...
       Artículo. 2018
    • "Candidate gene discovery in autoimmunity by using extreme phenotypes, next generation sequencing and whole exome capture" 

      "Johar, Angad S.; Anaya, Juan-Manuel; Andrews, Dan; Patel, Hardip R.; Field, Matthew; Goodnow, Chris; Arcos-Burgos, Mauricio"
      "Whole exome sequencing (WES) is a widely used strategy for detection of protein coding and splicing variants associated with inherited diseases. Many studies have shown that the strategy has been broad and proficient due ...
       Artículo. 2015
    • Cardiovascular disease in latin american patients with systemic lupus erythematosus: a cross-sectional study and a systematic review 

      Amaya-Amaya, Jenny-Carolina; Sarmiento Monroy, Juan Camilo; Caro-Moreno, Julián; Molano-González, Nicolas; Mantilla, Rubén D.; Rojas-Villarraga, Adriana; Anaya, Juan-Manuel
      Objective. This study was performed to determine the prevalence of and associated risk factors for cardiovascular disease (CVD) in Latin American (LA) patients with systemic lupus erythematosus (SLE). Methods. First, a ...
       Artículo. 2013
    • Comment on : Zika virus and Guillain–Barré syndrome in Bangladesh 

      Rodríguez, Yhojan; Anaya, Juan-Manuel
      Apreciaciones de los autores en un estudio prospectivo realizado entre 2011 y 2015 en Bangladesh, que trató de determinar si la presencia de ZIKV podría estar asociada con GBS de Geurtsvan Kessel et al.
       Editorial. 2018
    • "Comparison of the American-European Consensus Group Sjögren's syndrome classification criteria to newly proposed American College of Rheumatology criteria in a large, carefully characterised sicca cohort" 

      "Rasmussen, Astrid; Ice, John A; Li, He; Grundahl, Kiely; Kelly, Jennifer A; Radfar, Lida; Stone, Donald U; Hefner, Kimberly S; Anaya, Juan-Manuel; Rohrer, Michael; Gopalakrishnan, Rajaram; Houston, Glen D; Lewis, David M; Chodosh, James; Harley, John B; Hughes, Pamela; Maier-Moore, Jacen S; Montgomery, Courtney G; Rhodus, Nelson L; Farris, A Darise; Segal, Barbara M; Jonsson, Roland; Lessard, Christopher J; Scofield, R Hal; Sivils, Kathy L Moser"
      "Objective To compare the performance of the American-European Consensus Group (AECG) and the newly proposed American College of Rheumatology (ACR) classification criteria for Sjögren's Syndrome (SS) in a well-characterised ...
       Artículo. 2014
    • "Corrigendum to Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome" 

      "Harris, Valerie M.; Sharma, Rohan; Cavett, Joshua; Kurien, Biji T.; Liu, Ke; Koelsch, Kristi A.; Rasmussen, Astrid; Radfar, Lida; Lewis, David; Stone, Donald U.; Kaufman, C. Erick; Li, Shibo; Segal, Barbara; Wallace, Daniel J.; Weisman, Michael H.; Venuturupalli, Swamy; Kelly, Jennifer A.; Alarcon-Riquelme, Marta E.; Pons-Estel, Bernardo; Jonsson, Roland; Lu, Xianglan; Gottenberg, Jacques-Eric; Anaya, Juan-Manuel; Cunninghame-Graham, Deborah S.; Huang, Andrew J.W.; Brennan, Michael T.; Hughes, Pamela; Alevizos, Ilias; Miceli-Richard, Corinne; Keystone, Edward C.; Bykerk, Vivian P.; Hirschfield, Gideon; Xie, Gang; Siminovitch, Katherine A.; Ng, Wan-Fai; Nordmark, Gunnel; Bucher, Sara Magnusson; Eriksson, Per; Omdal, Roald; Rhodus, Nelson L.; Rischmueller, Maureen; Rohrer, Michael; Wahren-Herlenius, Marie; Witte, Torsten; Mariette, Xavier; Lessard, Christopher J.; Harley, John B.; Sivils, Kathy L.; Scofield, R. Hal"
      "In the published version of the above mentioned article, the author name “Katherine A Siminovitch” was not included. The authorship and affiliation given above is updated with all the author names and their respective ...
       other. 2018
    • Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production 

      "Deng, Yun; Zhao, Jian; Sakurai, Daisuke; Sestak, Andrea L; Osadchiy, Vadim; Langefeld, Carl D; Kaufman, Kenneth M; Kelly, Jennifer A; James, Judith A; Petri, Michelle A; Bae, Sang-Cheol; Alarcón-Riquelme, Marta E; Alarcón, Graciela S; Anaya, Juan-Manuel; Criswell, Lindsey A; Freedman, Barry I; Kamen, Diane L; Gilkeson, Gary S; Jacob, Chaim O; Merrill, Joan T; Gaffney, Patrick M; Sivils, Kathy Moser; Niewold, Timothy B; Ramsey-Goldman, Rosalind; Reveille, John D; Scofield, R Hal; Stevens, Anne M; Boackle, Susan A; Vilá, Luis M; Sohn, I I Woong; Lee, Seung; Chang, Deh-Ming; Song, Yeong Wook; Vyse, Timothy J; Harley, John B; Brown, Elizabeth E; Edberg, Jeffrey C; Kimberly, Robert P; Cantor, Rita M; Hahn, Bevra H; Grossman, Jennifer M; Tsao, Betty P"
      "Objectives Following up the systemic lupus erythematosus (SLE) genome-wide association studies (GWAS) identification of NMNAT2 at rs2022013, we fine-mapped its 150a €...kb flanking regions containing NMNAT2 and SMG7 in a ...
       Artículo. 2016
    • Enfermedad tiroidea autoinmune en pacientes colombianos con lupus eritematoso sistémico 

      Franco Aristizabal, Juan Sebastian; Amaya-Amaya, Jenny-Carolina; Molano-González, Nicolas; Rodríguez-Jímenez, Mónica; Acosta-Ampudia, Yeny; Anaya, Juan-Manuel
      Objetivos: Determinar la prevalencia y los factores asociados con el desarrollo de hipotiroidismo autoinmune (HA) en una cohorte de pacientes con lupus eritematoso sistémico (LES), y analizar la información actual en cuanto ...
       Trabajo de grado. 2015
    • Espondiloartropatias seronegativas y viceversa 

      Perez-Fernandez, Oscar-Mauricio; Mantilla, Rubén D.; Anaya, Juan-Manuel
      Introducción. Las Espondiloartropatias Seronegativas (EAS) son un grupo de enfermedades interrelacionadas que presentan compromiso inflamatorio articular y hallazgos extraarticulares. Por otra parte, las Enfermedades ...
       Trabajo de grado. 2011