Browsing by Author "Patarroyo, Manuel A."
Now showing items 1-20 of 104
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3D Analysis of the TCR/pMHCII Complex Formation in Monkeys Vaccinated with the First Peptide Inducing Sterilizing Immunity against Human Malaria
T-cell receptor gene rearrangements were studied in Aotus monkeys developing high antibody titers and sterilizing immunity against the Plasmodium falciparum malaria parasite upon vaccination with the modified synthetic ...
Artículo. 2010
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A highly infective plasmodium vivax strain adapted to Aotus monkeys: quantitative haematological and molecular determinations useful for P. vivax malaria vaccine development
The New World primate Aotus nancymaae is susceptible to infection by the human malaria parasite Plasmodium vivax and has therefore been recommended by the World Health Organization as a model for malaria vaccine candidate ...
Artículo. 2003
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A novel loop-mediated isothermal amplification-based test for detecting Neospora caninum DNA
Background: Neospora caninum is a cyst-forming, coccidian parasite which is known to cause neurological disorders in dogs and abortion and neonatal mortality in cows and other livestock. This study reports the development ... Artículo. 2017
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A pre-PEXEL histidine-rich protein II erythrocyte binding peptide as a new way for anti-malarial vaccine development
The Plasmodium falciparum malaria parasite produces several proteins characterised by an unusually high histidine content in infected red blood cells (iRBC). The histidine-rich protein II (HRP-II) is synthesised throughout ... Artículo. 2007
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A Trypanosoma cruzi Genome Tandem Repetitive Satellite DNA Sequence as a Molecular Marker for a LAMP Assay for Diagnosing Chagas' Disease
Chagas' disease is a neglected tropical disease caused by Trypanosoma cruzi which is endemic throughout Latin America and is spread by worldwide migration. Diagnosis is currently limited to serological and molecular ... Artículo. 2020
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An epidemiological and molecular study regarding the spread of vancomycin-resistant Enterococcus faecium in a teaching hospital in Bogotá, Colombia 2016
Background: Enterococcus faecium is ranked worldwide as one of the top ten pathogens identified in healthcare-associated infections (HAI) and is classified as one of the high priority pathogens for research and development ... Artículo. 2019
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Annotation and characterization of the Plasmodium vivax rhoptry neck protein 4 (PvRON4)
Background: The tight junction (TJ) is one of the most important structures established during merozoite invasion of host cells and a large amount of proteins stored in Toxoplasma and Plasmodium parasites’ apical organelles ... Artículo. 2013
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Association of HIV status with infection by multiple HPV types
Objectives: To identify the clinical and demographic characteristics of HIV-positive and HIV-negative women infected by multiple HPV types. Methods: 1399 women participated in the study (240 HIV-positive and 1159 HIV-negative ... Artículo. 2018
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Behavior and abundance of Anopheles darlingi in communities living in the Colombian Amazon riverside
In the past few years, relative frequencies of malaria parasite species in communities living in the Colombian Amazon riverside have changed, being Plasmodium vivax (61.4%) and Plasmodium malariae (43.8%) the most frequent. ... Artículo. 2019
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Cell-Peptide Specific Interaction Can Inhibit Mycobacterium tuberculosis H37Rv Infection
Studying proteins from the M. tuberculosis H37Rv envelop is important for understanding host-pathogen interaction regarding bacterial infection and survival within a host; such knowledge is indispensable regarding studies ... Artículo. 2016
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Characterising a microsatellite for DRB typing in Aotus vociferans and Aotus nancymaae (Platyrrhini)
Non-human primates belonging to the Aotus genus have been shown to be excellent experimental models for evaluating drugs and vaccine candidates against malaria and other human diseases. The immune system of this animal ... Artículo. 2014
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Characterising atypical Candida albicans clinical isolates from six third-level hospitals in Bogotá, Colombia
Background: Candida species are the most frequently found fungal pathogens causing nosocomial disease in a hospital setting. Such species must be correctly identified to ensure that appropriate control measures are taken ... Artículo. 2015
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Characterizing PvARP, a novel Plasmodium vivax antigen
Background Plasmodium vivax continues to be the most widely distributed malarial parasite species in tropical and sub-tropical areas, causing high morbidity indices around the world. Better understanding of the proteins ... Artículo. 2013
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Chlamydia trachomatis frequency in a cohort of HPV-infected colombian women
Background Chlamydia trachomatis (C. trachomatis), an obligate intracellular bacterium, is the commonest infectious bacterial agent of sexual transmission throughout the world. It has been shown that the presence of this ... Artículo. 2016
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Community-acquired infection with hypervirulent Clostridium difficile isolates that carry different toxin and antibiotic resistance loci: A case report
Background: Clostridium difficile infection (CDI) leads to the onset of antibiotic-associated diarrhea (AAD) and a wide range of gastrointestinal pathologies. Currently, CDI is one of the most important opportunistic ... Artículo. 2017
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Comparative genomics identifies potential virulence factors in Clostridium tertium and C. paraputrificum
Some well-known Clostridiales species such as Clostridium difficile and C. perfringens are agents of high impact diseases worldwide. Nevertheless, other foreseen Clostridiales species have recently emerged such as Clostridium ... Artículo. 2019
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Computational prediction and experimental assessment of secreted/surface proteins from Mycobacterium tuberculosis H37Rv
The mycobacterial cell envelope has been implicated in the pathogenicity of tuberculosis and therefore has been a prime target for the identification and characterization of surface proteins with potential application in ... Artículo. 2010
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Conserved regions from Plasmodium falciparum MSP11 specifically interact with host cells and have a potential role during merozoite invasion of red blood cells
Despite significant global efforts, a completely effective vaccine against Plasmodium falciparum, the species responsible for the most serious form of malaria, has not been yet obtained. One of the most promising approaches ... Artículo. 2010
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Cuantificación de citoquinas de mono Aotus por RT-PCR cuantitativa en tiempo real
Aotus spp. Los monos se consideran el modelo ideal para estudiar el progreso de la infección de malaria y la respuesta inmune que provoca. Describimos el uso de una técnica desarrollada recientemente, RT-PCR cuantitativa ... Artículo. 2004
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Determining Clostridium difficile intra-taxa diversity by mining multilocus sequence typing databases
Background: Multilocus sequence typing (MLST) is a highly discriminatory typing strategy; it is reproducible and scalable. There is a MLST scheme for Clostridium difficile (CD), a gram positive bacillus causing different ... Artículo. 2017
