Now showing items 1-9 of 9

    • Epigenetics and autoimmune diseases 

      Quintero-Ronderos, Paula; Montoya-Ortiz, Gladis
      Epigenetics is defined as the study of all inheritable and potentially reversible changes in genome function that do not alter the nucleotide sequence within the DNA. Epigenetic mechanisms such as DNA methylation, histone ...
       Artículo. 2012
    • How does age at onset influence the outcome of autoimmune diseases? 

      Amador-Patarroyo, Manuel-José; Rodríguez-Rodríguez, Alberto; Montoya-Ortiz, Gladis
      The age at onset refers to the time period at which an individual experiences the first symptoms of a disease. In autoimmune diseases (ADs), these symptoms can be subtle but are very relevant for diagnosis. They can appear ...
       Artículo. 2012
    • Immunosenescence, Aging, and Systemic Lupus Erythematous 

      Montoya-Ortiz, Gladis
      Senescence is a normal biological process that occurs in all organisms and involves a decline in cell functions. This process is caused by molecular regulatory machinery alterations, and it is closely related to telomere ...
       Artículo. 2013
    • Immunosenescence, aging, and systemic lupus erythematous. 

      Montoya-Ortiz, Gladis
      La senescencia es un proceso biológico normal que ocurre en todos los organismos e implica una disminución en las funciones celulares. Este proceso es causado por alteraciones de la maquinaria de regulación molecular, y ...
       Artículo. 2013
    • Organic solvents as risk factor for autoimmune diseases: a systematic review and meta-analysis 

      Barragán Martínez, Carolina; Speck Hernández, Cesar A.; Montoya-Ortiz, Gladis; Mantilla, Rubén D.; Anaya, Juan-Manuel; Rojas-Villarraga, Adriana
      Background: Genetic and epigenetic factors interacting with the environment over time are the main causes of complex diseases such as autoimmune diseases (ADs). Among the environmental factors are organic solvents (OSs), ...
       Artículo. 2012
    • Silicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid Arthritis 

      Speck-Hernandez, Cesar A.; Montoya-Ortiz, Gladis
      Silicon is one of the most common chemicals on earth. Several compounds such as silica, asbestos, silicone or, nanoparticles are built from tetrahedral units with silicon as the central atom. Despite these, structural ...
       Artículo. 2012
    • Silicon, a possible link between environmental exposure and autoimmune diseases: The case of rheumatoid arthritis. 

      Speck-Hernandez, Cesar A; Montoya-Ortiz, Gladis
      Silicon is one of the most common chemicals on earth. Several compounds such as silica, asbestos, silicone or, nanoparticles are built from tetrahedral units with silicon as the central atom. Despite these, structural ...
       Artículo. 2012
    • Usefulness of Patients-Reported Outcomes in Rheumatoid Arthritis Focus Group 

      Amaya-Amaya, Jenny; Botello-Corzo, Diana; Calixto, Omar-Javier; Calderón-Rojas, Rolando; Domínguez, Aura-Maria; Cruz-Tapias, Paola; Montoya-Ortiz, Gladis; Mantilla, Ruben-Dario; Anaya, Juan-Manuel; Rojas-Villarraga, Adriana
      Objective. Patient-reported outcomes (PROs) have become an essential part of the assessment of patients with rheumatoid arthritis (RA). We aimed to evaluate the agreement and correlation between PROs and the physician's ...
       Artículo. 2012
    • Usefulness of patients-reported outcomes in rheumatoid arthritis focus group. 

      Amaya-Amaya, Jenny; Botello-Corzo, Diana; Calixto, Omar-Javier; Calderon-Rojas, Rolando; Dominguez, Aura-Maria; Cruz-Tapias, Paola; Montoya-Ortiz, Gladis; Mantilla, Ruben-Dario; Anaya, Juan-Manuel; Rojas-Villarraga, Adriana
      Patient-reported outcomes (PROs) have become an essential part of the assessment of patients with rheumatoid arthritis (RA). We aimed to evaluate the agreement and correlation between PROs and the physician's measurements. ...
       Artículo. 2012