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dc.contributor.advisorÁlvarez, Martha Isabel 
dc.contributor.advisorVillaveces, Mariana 
dc.creatorRodriguez Basto, Lucia Marcela 
dc.date.accessioned2017-12-07T17:42:36Z
dc.date.available2017-12-07T17:42:36Z
dc.date.created2017-11-24
dc.date.issued2017
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/14136
dc.descriptionSe trata de un revisión sistemática de la literatura para evaluar la evidencia sobre la efectividad de la vacuna acelular antipertussis mediante la medición de los niveles de anticuerpos contra B. pertussis en el neonato e infante menor de dos meses, reflejando el paso transplacentario de anticuerpos maternos contra la tosferina.
dc.description.abstractBackround: With the worldwide resurgence of pertusiss in 2011, and letal infection in neonates and infants under two months of age, new vaccination strategies have been sought to reduce infant mortality and prevent fatal cases of Bordetella pertussis, including vaccination of pregnant women, based on the effective passage of maternal antibodies to the neonate. Methods: Systematic review of articles literature to evaluate the effectiveness of vertical transference of antibodies to neonates with the application of the acellular antipertussis vaccine to provide protection to the newborn and the infant under 2 months – old. Results: After a rigorous search, 18 articles were included for analysis and extraction of evidence. The effectiveness of the Tdap vaccine exceeded 90% in neonates, taking into account the levels of antibodies in the same. The reactogenicity, in generall was low. Discussion: The vaccine against pertussis in pregnant women appears to be a safe, effective and accepted strategy to protect the newborn during the first weeks of life. For this reason it has been recommended for all pregnant women dduring each pregnancy, a measure adopted in different countries of Europe and in America including our country. Conclusion: Available evidence suggests that the Tdap vaccine may be recommended in pregnant women between week 27-36 of gestation, a period in which there is a greater transplacental passage of antibodies against pertussis. Accelerating Tdap in pregnant women is an effective strategy with no side effects and low cost. . Key words: Effectiveness, passive immunization, anti-pertussis acellular vaccines, newborn.
dc.format.mimetypeapplication/pdf
dc.language.isospa
dc.sourcereponame:Repositorio Institucional EdocUR
dc.sourceinstname:Universidad del Rosario
dc.subjectEfectividad
dc.subjectInmunización pasiva
dc.subjectVacuna acelular antipertusis
dc.subjectRecién nacido
dc.titleEfectividad de la vacuna Acelular Antipertusis en el embarazo y su protección al recién nacido : revisión sistemática
dc.typemasterThesis
dc.publisherUniversidad del Rosario
dc.creator.degreeEspecialista en Pediatría
dc.publisher.programEspecialización en Pediatría
dc.publisher.departmentFacultad de medicina
dc.subject.keywordEffectiveness
dc.subject.keywordPassive immunization
dc.subject.keywordAnti-pertussis
dc.subject.keywordAcellular vaccines
dc.subject.keywordNewborn
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.subject.decsVacunas contra Difteria, Tétanos y Tos Ferina Acelular Quitar
dc.subject.decsAnticuerpos
dc.subject.decsRecién Nacido
dc.type.spaTrabajo de grado
dc.rights.accesoAbierto (Texto Completo)
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
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dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.


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