Show simple item record

dc.contributor.advisorRamírez-Vélez, Robinson 
dc.contributor.advisorCorrea Bautista, Jorge Enrique 
dc.creatorVelasco-Orjuela, Gina P 
dc.creatorDomínguez-Sanchéz, Maria A 
dc.creatorCorrea Bautista, Jorge Enrique 
dc.creatorTriana Reina, Héctor Reynaldo 
dc.creatorGarcía-Hermoso, Antonio 
dc.creatorPeña-Ibagon, Jhonatan C 
dc.creatorIzquierdo, Mikel 
dc.creatorCadore, Eduardo 
dc.creatorHackney, Anthony C 
dc.creatorRamírez-Vélez, Robinson
dc.description.abstractThe purpose of this study was to compare the hormonal responses to one session of high-intensity interval training (HIIT, 4×4 min intervals at 85–95% maximum heart rate [HRmax], interspersed with 4 min of recovery at 75–85% HRmax), resistance training (RT at 50-70% of one repetition maximum 12-15 repetitions per set with 60s of recovery) or both (HIIT+RT) exercise protocol in a cohort of physical inactivity, overweight adults (age 18–30 years old). Randomized, parallel-group clinical trial among fifty-one men (23.6±3.5 yr; 83.5±7.8 kg; 28.0±1.9 kg/m2), physical inactivity (i.e. <150 min of moderate-intensity exercise per week for greater than 6 months), with abdominal obesity (waist circumference ≥ 90 cm) or body mass index ≥ 25 and ≤ 30 kg/m2 were randomized to the following 4 groups: high-intensity interval training (n=14), resistance training (n=12), combined high- intensity interval and resistance training (n=13), or non-exercising control (n=12). Cortisol, total- and free-testosterone and total-testosterone/cortisol-ratio (T/C) assessments (all in serum) were determined before (pre) and 1-min post-exercise for each protocol session. Decreases in cortisol levels were −57.08 (95%CI, −75,58 to −38,58; P=0.001; ɳ 2=0.61) and −37.65 (95%CI, −54,36 to −20,93; P=0.001; ɳ 2=0.51) in the HIIT and control group, respectively. Increases in T/C ratio were 0.022 (95%CI, 0.012 to 0.031; P=0.001; ɳ 2=0.49) and 0.015 (95%CI, 0.004 to 0.025; P=0.007; ɳ 2=0.29) in the HIIT and control group, respectively. In per-protocol analyses revealed significant change in cortisol levels [interaction effect F(7.777), ɳ 2=0.33] and T/C ratio [interaction effect F(5.298), ɳ 2=0.25] between groups over time. The present data indicate a HIIT reduced cortisol and increased total- testosterone/cortisol-ratio levels significantly in physical inactive adults. Further study is required to determine the biological importance of these changes in hormonal responses in overweight men.
dc.rightsAtribución-NoComercial-SinDerivadas 2.5 Colombia
dc.sourceinstname:Universidad del Rosario
dc.sourcereponame:Repositorio Institucional EdocUR
dc.subjectBlood hormones
dc.titleAcute effects of high-intensity interval, resistance or combined exercise protocols on testosterone – cortisol responses in inactive overweight individuals
dc.publisherUniversidad del Rosario
dc.creator.degreeMagíster en actividad física y salud
dc.publisher.programMaestría en Actividad Física y Salud
dc.publisher.departmentFacultad de medicina
dc.subject.decsObesidad Abdominal
dc.type.spaTesis de maestría
dc.rights.accesoAbierto (Texto Completo)
dc.source.bibliographicCitationHerrán OF, Patiño GA, Del Castillo SE. Dietary transition and excess weight in adults according to the Encuesta de la Situación Nutricional en Colombia, 2010. Biomedica. 2016;36(1):109-20.
dc.source.bibliographicCitationKohl HW, Craig CL, Lambert EV, Inoue S, Alkandari JR, Leetongin G, et al. The pandemic of physical inactivity: global action for public health. Lancet. 2012;380(9838):294-305.
dc.source.bibliographicCitationBekaert M, Van Nieuwenhove Y, Calders P, Cuvelier CA, Batens AH, Kaufman JM, et al. Determinants of testosterone levels in human male obesity. Endocrine. 2015;50(1):202-11.
dc.source.bibliographicCitationVandewalle S, De Schepper J, Kaufman JM. Androgens and obesity in male adolescents. Curr Opin Endocrinol Diabetes Obes. 2015;22(3):230-7.
dc.source.bibliographicCitationO'Leary CB, Hackney AC. Acute and chronic effects of resistance exercise on the testosterone and cortisol responses in obese males: a systematic review. Physiol Res. 2014;63(6):693-704.
dc.source.bibliographicCitationAkishita M, Hashimoto M, Ohike Y, Ogawa S, Iijima K, Eto M, et al. Low testosterone level as a predictor of cardiovascular events in Japanese men with coronary risk factors. Atherosclerosis. 2010;210(1):232-6.
dc.source.bibliographicCitationRubin DA, Hackney AC. Inflammatory cytokines and metabolic risk factors during growth and maturation: influence of physical activity. Med Sport Sci. 2010;55:43-55.
dc.source.bibliographicCitationBuch A, Kis O, Carmeli E, Keinan-Boker L, Berner Y, Barer Y, et al. Circuit resistance training is an effective means to enhance muscle strength in older and middle aged adults: A systematic review and meta-analysis. Ageing Res Rev. 2017;37:16-27.
dc.source.bibliographicCitationSylta Ø, Tønnessen E, Sandbakk Ø, Hammarström D, Danielsen J, Skovereng K, et al. Effects of High-Intensity Training on Physiological and Hormonal Adaptions in Well- Trained Cyclists. Med Sci Sports Exerc. 2017;49(6):1137-46.
dc.source.bibliographicCitationMangine GT, Hoffman JR, Gonzalez AM, Townsend JR, Wells AJ, Jajtner AR, et al. Exercise-Induced Hormone Elevations Are Related to Muscle Growth. J Strength Cond Res. 2017;31(1):45-53.
dc.source.bibliographicCitationZinner C, Wahl P, Achtzehn S, Reed JL, Mester J. Acute hormonal responses before and after 2 weeks of HIT in well trained junior triathletes. Int J Sports Med. 2014;35(4):316-22.
dc.source.bibliographicCitationWahl P, Mathes S, Köhler K, Achtzehn S, Bloch W, Mester J. Acute metabolic, hormonal, and psychological responses to different endurance training protocols. Horm Metab Res. 2013;45(11):827-33.
dc.source.bibliographicCitationViru A, Viru M. Cortisol--essential adaptation hormone in exercise. Int J Sports Med. 2004;25(6):461-4.
dc.source.bibliographicCitationWest DW, Burd NA, Tang JE, Moore DR, Staples AW, Holwerda AM, et al. Elevations in ostensibly anabolic hormones with resistance exercise enhance neither training-induced muscle hypertrophy nor strength of the elbow flexors. J Appl Physiol (1985). 2010;108(1):60-7.
dc.source.bibliographicCitationHoogeveen AR, Zonderland ML. Relationships between testosterone, cortisol and performance in professional cyclists. Int J Sports Med. 1996;17(6):423-8.
dc.source.bibliographicCitationChan J, Sauvé B, Tokmakejian S, Koren G, Van Uum S. Measurement of cortisol and testosterone in hair of obese and non-obese human subjects. Exp Clin Endocrinol Diabetes. 2014;122(6):356-62.
dc.source.bibliographicCitationSheikholeslami-Vatani D, Siahkouhian M, Hakimi M, Ali-Mohammadi M. The effect of concurrent training order on hormonal responses and body composition in obese men. Science & Sports. 2015;30(6):335-41.
dc.source.bibliographicCitationMcMurray RG, Hackney AC. Interactions of metabolic hormones, adipose tissue and exercise. Sports Med. 2005;35(5):393-412.
dc.source.bibliographicCitation(WHO) WHO. Global Strategy on Diet, Physical Activity and Health [Available from:
dc.source.bibliographicCitationServices UDoHaH. Physical Activity Guidelines AdvisoryCommittee. Physical Activity Guidelines Advisory Committee Report. [Available from:
dc.source.bibliographicCitationRamírez-Vélez R, Hernandez A, Castro K, Tordecilla-Sanders A, González-Ruíz K, Correa-Bautista JE, et al. High Intensity Interval- vs Resistance or Combined- Training for Improving Cardiometabolic Health in Overweight Adults (Cardiometabolic HIIT-RT Study): study protocol for a randomised controlled trial. Trials. 2016;17(1):298.
dc.source.bibliographicCitationGraf S, Karsegard VL, Viatte V, Maisonneuve N, Pichard C, Genton L. Comparison of three indirect calorimetry devices and three methods of gas collection: a prospective observational study. Clin Nutr. 2013;32(6):1067-72.
dc.source.bibliographicCitationOrganization WH. Obesity: preventing and managing the global epidemic. Reportof a WHO consultation on obesity. 1997.
dc.source.bibliographicCitationMarfell-Jones M OT, Stewart, A. International Standards for AnthropometricAssessment; ISAK: Potchefstroom, South Africa. 2006.
dc.source.bibliographicCitationRodríguez-Rodríguez F, Cristi-Montero C, González-Ruíz K, Correa-Bautista JE, Ramírez-Vélez R. Bioelectrical Impedance Vector Analysis and Muscular Fitness in Healthy Men. Nutrients. 2016;8(7).
dc.source.bibliographicCitationKraemer WJ, Ratamess NA. Hormonal responses and adaptations to resistance exercise and training. Sports Med. 2005;35(4):339-61.
dc.source.bibliographicCitationCadore EL, Lhullier FL, Brentano MA, da Silva EM, Ambrosini MB, Spinelli R, et al. Hormonal responses to resistance exercise in long-term trained and untrained middle- aged men. J Strength Cond Res. 2008;22(5):1617-24.
dc.source.bibliographicCitationWilloughby DS, Taylor L. Effects of sequential bouts of resistance exercise on androgen receptor expression. Med Sci Sports Exerc. 2004;36(9):1499-506.
dc.source.bibliographicCitationInoue K, Yamasaki S, Fushiki T, Kano T, Moritani T, Itoh K, et al. Rapid increase in the number of androgen receptors following electrical stimulation of the rat muscle. Eur J Appl Physiol Occup Physiol. 1993;66(2):134-40.
dc.source.bibliographicCitationGalbo H, Hummer L, Peterson IB, Christensen NJ, Bie N. Thyroid and testicular hormone responses to graded and prolonged exercise in man. Eur J Appl Physiol Occup Physiol. 1977;36(2):101-6.
dc.source.bibliographicCitationHackney AC. Testosterone, the hypothalamo-pituitary-testicular axis, and endurance exercise training: A review. Biology of Sport , ; 1996. p. 85 - 98.
dc.source.bibliographicCitationFahrner C, Hackney A. Effects of endurance exercise on free testosterone concentration and the binding affinity of sex hormone binding globulin (SHBG). International journal of sports medicine. 1998;19(01):12-5.
dc.source.bibliographicCitationMeskaitis V, Harman F, Volek J, Nindl B, Kraemer W, Weinstok D, et al. Effects of exercise on testosterone and nitric oxide production in the rats testis. J Androl Suppl. 1997;31.
dc.source.bibliographicCitationLu SS, Lau CP, Tung YF, Huang SW, Chen YH, Shih HC, et al. Lactate and the effects of exercise on testosterone secretion: evidence for the involvement of a cAMP- mediated mechanism. Med Sci Sports Exerc. 1997;29(8):1048-54.
dc.source.bibliographicCitationvan Kerkhof LW, Van Dycke KC, Jansen EH, Beekhof PK, van Oostrom CT, Ruskovska T, et al. Diurnal Variation of Hormonal and Lipid Biomarkers in a Molecular Epidemiology-Like Setting. PLoS One. 2015;10(8):e0135652.
dc.source.bibliographicCitationSato K, Iemitsu M. Exercise and sex steroid hormones in skeletal muscle. J Steroid Biochem Mol Biol. 2015;145:200-5.
dc.source.bibliographicCitationWilkerson JE, Horvath SM, Gutin B. Plasma testosterone during treadmill exercise. J Appl Physiol Respir Environ Exerc Physiol. 1980;49(2):249-53.
dc.source.bibliographicCitationKokalas N, Tsalis G, Tsigilis N, Mougios V. Hormonal responses to three training protocols in rowing. Eur J Appl Physiol. 2004;92(1-2):128-32.
dc.source.bibliographicCitationHough JP, Papacosta E, Wraith E, Gleeson M. Plasma and salivary steroid hormone responses of men to high-intensity cycling and resistance exercise. J Strength Cond Res. 2011;25(1):23-31.
dc.source.bibliographicCitationWelsh TH, Bambino TH, Hsueh AJ. Mechanism of glucocorticoid-induced suppression of testicular androgen biosynthesis in vitro. Biol Reprod. 1982;27(5):1138-46.
dc.source.bibliographicCitationCadore EL, Izquierdo M, dos Santos MG, Martins JB, Rodrigues Lhullier FL, Pinto RS, et al. Hormonal responses to concurrent strength and endurance training with different exercise orders. J Strength Cond Res. 2012;26(12):3281-8.
dc.source.bibliographicCitationCumming DC, Quigley ME, Yen SS. Acute suppression of circulating testosterone levels by cortisol in men. J Clin Endocrinol Metab. 1983;57(3):671-3.
dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.

Files in this item


This item appears in the following Collection(s)

Show simple item record

Atribución-NoComercial-SinDerivadas 2.5 Colombia
Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 2.5 Colombia