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dc.creatorCamargo-Ayala, Paola Andrea 
dc.creatorCubides, Juan Ricardo 
dc.creatorNiño, Carlos Hernando 
dc.creatorCamargo, Milena 
dc.creatorRodríguez-Celis, Carlos Arturo 
dc.creatorQuiñones, Teódulo 
dc.creatorSánchez-Suárez, Lizeth 
dc.creatorPatarroyo, Manuel Elkin 
dc.creatorPatarroyo, Manuel A. 
dc.date.accessioned2019-01-25T20:31:52Z
dc.date.available2019-01-25T20:31:52Z
dc.date.created2016
dc.date.issued2016 
dc.identifier.issnISSN 1932-6203
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/18930
dc.descriptionMalaria is a worldwide public health problem; parasites from the genus Plasmodium are the aetiological agent for this disease. The parasites are mostly diagnosed by conventional microscopy-based techniques; however, their limitations have led to under-registering the reported prevalence of Plasmodium species. This study has thus been aimed at evaluating the infection and coinfection prevalence of 3 species of Plasmodium spp., in an area of the Colombian Amazon region. Blood samples were taken from 671 symptomatic patients by skin puncture; a nested PCR amplifying the 18S ssRNA region was used on all samples to determine the presence of P. vivax, P. malariae and P. falciparum. Statistical analysis determined infection and coinfection frequency; the association between infection and different factors was established. The results showed that P. vivax was the species having the greatest frequency in the study population (61.4%), followed by P. malariae (43.8%) and P. falciparum (11.8%). The study revealed that 35.8% of the population had coinfection, the P. vivax/P. malariae combination occurring most frequently (28.3%); factors such as age, geographical origin and clinical manifestations were found to be associated with triple-infection. The prevalence reported in this study differed from previous studies in Colombia; the results suggest that diagnosis using conventional techniques could be giving rise to underestimating some Plasmodium spp. species having high circulation rates in Colombia (particularly in the Colombian Amazon region). The present study's results revealed a high prevalence of P. malariae and mixed infections in the population being studied. The results provide relevant information which should facilitate updating the epidemiological panorama and species' distribution so as to include control, prevention and follow-up measures. © 2016 Camargo-Ayala et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.relation.ispartofPLoS ONE, ISSN: 1932-6203, Vol. 11/No. 7 (2016); pp.1-17
dc.relation.urihttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0159968&type=printable
dc.rights.uri
dc.subjectDouble Stranded Rna
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAge
dc.subjectAged
dc.subjectArticle
dc.subjectBlood Sampling
dc.subjectChild
dc.subjectChill
dc.subjectColombia
dc.subjectControlled Study
dc.subjectCross-Sectional Study
dc.subjectDiarrhea
dc.subjectDisease Association
dc.subjectEndemic Species
dc.subjectFemale
dc.subjectFever
dc.subjectGeographic Origin
dc.subjectHeadache
dc.subjectHuman
dc.subjectMajor Clinical Study
dc.subjectMalaria Falciparum
dc.subjectMale
dc.subjectMixed Infection
dc.subjectNonhuman
dc.subjectParasite Prevalence
dc.subjectPlasmodium Falciparum
dc.subjectPlasmodium Malariae
dc.subjectPlasmodium Malariae Infection
dc.subjectPlasmodium Vivax
dc.subjectPlasmodium Vivax Malaria
dc.subjectPolymerase Chain Reaction
dc.subjectRisk Factor
dc.subjectUrine Color
dc.subjectVery Elderly
dc.subjectVomiting
dc.subjectClassification
dc.subjectEndemic Disease
dc.subjectGenetics
dc.subjectMalaria
dc.subjectMolecular Diagnosis
dc.subjectParasitology
dc.subjectPlasmodium
dc.subjectPrevalence
dc.subjectColombia
dc.subjectEndemic Diseases
dc.subjectHumans
dc.subjectMalaria
dc.subjectMolecular Diagnostic Techniques
dc.subjectPlasmodium
dc.subjectPrevalence
dc.subject.ddcEnfermedades 
dc.subject.lembMalaria
dc.subject.lembPlasmodium
dc.titleHigh plasmodium malariae prevalence in an endemic area of the colombian amazon region
dc.typearticle
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.type.spaArtículo
dc.rights.accesoAbierto (Texto Completo)
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.source.bibliographicCitationMalaria rapid diagnostic test performance (2012) Results of who Product Testing of Malaria RDTs: Round, 4, p. 140. , WHO, TDR, FIND 2012
dc.rights.cchttps://creativecommons.org/licenses/by/4.0/
dc.creator.googleCamargo-Ayala, Paola Andrea
dc.creator.googleCubides, Juan Ricardo
dc.creator.googleNiño, Carlos Hernando
dc.creator.googleCamargo, Milena
dc.creator.googleRodríguez-Celis, Carlos Arturo
dc.creator.googleQuiñones, Teódulo
dc.creator.googleSánchez-Suárez, Lizeth
dc.creator.googlePatarroyo, Manuel Elkin
dc.creator.googlePatarroyo, Manuel Alfonso


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