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dc.creatorAmador-Patarroyo, Manuel J. 
dc.creatorArbelaez, Juan Guillermo 
dc.creatorMantilla, Ruben D. 
dc.creatorRodriguez-Rodriguez, Alberto 
dc.creatorCárdenas-Roldán, Jorge 
dc.creatorPineda-Tamayo, Ricardo 
dc.creatorGuarin, Mayra R. 
dc.creatorKleine, Liliana Lopez 
dc.creatorRojas-Villarraga, Adriana 
dc.creatorAnaya, Juan-Manuel 
dc.date.accessioned2020-05-25T23:55:53Z
dc.date.available2020-05-25T23:55:53Z
dc.date.created2012
dc.identifier.issn10959157
dc.identifier.issn08968411
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/22253
dc.description.abstractThe coexistence of autoimmune diseases (i.e., polyautoimmunity) in Sjögren's syndrome (SS) was investigated in a cross-sectional study involving 410 patients. Logistic regression analysis and the Rogers and Tanimoto index were used to evaluate risk factors and clustering, respectively. There were 134 (32.6%) patients with polyautoimmunity. The most frequent and closer coexistent diseases were autoimmune thyroid disease (21.5%), rheumatoid arthritis (8.3%), systemic lupus erythematosus (7.6%), and inflammatory bowel disease (0.7%) which together constituted a cluster group. There were 35 (8.5%) patients with multiple autoimmune syndrome. Besides disease duration, a history of habitual smoking and spontaneous abortion were found to be risk factors for the developing of polyautoimmunity. This study discloses a high prevalence of polyautoimmunity in SS, its associated risk factors and the grouping pattern of such a condition. These results may serve to define plausible approaches to study the common mechanisms of autoimmune diseases. © 2012 Elsevier Ltd.
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.relation.ispartofJournal of Autoimmunity, ISSN:10959157, 08968411, Vol.39, No.3 (2012); pp. 199-205
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84865394612&doi=10.1016%2fj.jaut.2012.05.008&partnerID=40&md5=f2a4bdeb63cbec2d5cb1ec6bdff7b440
dc.titleSjögren's syndrome at the crossroad of polyautoimmunity
dc.typearticle
dc.subject.keywordAdult
dc.subject.keywordautoimmune
dc.subject.keywordrheumatoid
dc.subject.keywordspontaneous
dc.subject.keywordAntiphospholipid syndrome
dc.subject.keywordsystemic
dc.subject.keywordArticle
dc.subject.keywordAutoimmune disease
dc.subject.keywordAutoimmune hepatitis
dc.subject.keywordAutoimmune thyroiditis
dc.subject.keywordCigarette smoking
dc.subject.keywordComorbidity
dc.subject.keywordCross-sectional study
dc.subject.keywordDisease duration
dc.subject.keywordEnteritis
dc.subject.keywordFemale
dc.subject.keywordHuman
dc.subject.keywordMajor clinical study
dc.subject.keywordMale
dc.subject.keywordMultiple sclerosis
dc.subject.keywordPernicious anemia
dc.subject.keywordPrevalence
dc.subject.keywordPriority journal
dc.subject.keywordPsoriasis
dc.subject.keywordRheumatoid arthritis
dc.subject.keywordRisk factor
dc.subject.keywordSjoegren syndrome
dc.subject.keywordSpontaneous abortion
dc.subject.keywordSystemic lupus erythematosus
dc.subject.keywordSystemic sclerosis
dc.subject.keywordVasculitis
dc.subject.keywordVitiligo
dc.subject.keywordAbortion
dc.subject.keywordAdult
dc.subject.keywordArthritis
dc.subject.keywordAutoantibodies
dc.subject.keywordCross-sectional studies
dc.subject.keywordFemale
dc.subject.keywordHumans
dc.subject.keywordInflammatory bowel diseases
dc.subject.keywordLupus erythematosus
dc.subject.keywordMale
dc.subject.keywordMiddle aged
dc.subject.keywordPregnancy
dc.subject.keywordRegression analysis
dc.subject.keywordRisk factors
dc.subject.keywordSjogren's syndrome
dc.subject.keywordSmoking
dc.subject.keywordThyroiditis
dc.subject.keywordAbortion
dc.subject.keywordAutoimmune disease
dc.subject.keywordMultiple autoimmune syndrome
dc.subject.keywordPolyautoimmunity
dc.subject.keywordSjögren's syndrome
dc.subject.keywordSmoking
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.type.spaArtículo
dc.rights.accesoAbierto (Texto Completo)
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.identifier.doihttps://doi.org/10.1016/j.jaut.2012.05.008
dc.relation.citationEndPage205
dc.relation.citationIssueNo. 3
dc.relation.citationStartPage199
dc.relation.citationTitleJournal of Autoimmunity
dc.relation.citationVolumeVol. 39
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR


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