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dc.creatorNieves E. 
dc.creatorTobón L.F. 
dc.creatorRíos D.I. 
dc.creatorIsaza A. 
dc.creatorRamírez M. 
dc.creatorBeltrán J.A. 
dc.creatorGarzón-Ospina D. 
dc.creatorPatarroyo M.A. 
dc.creatorGómez A. 
dc.date.accessioned2020-05-25T23:56:41Z
dc.date.available2020-05-25T23:56:41Z
dc.date.created2011
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/22486
dc.description.abstract"Background: Bacterial translocation (BT) describes the passage of bacteria residing into the gastrointestinal tract, through the intestinal mucosa barrier to sterile tissues such as mesenteric lymph nodes (MLN) and other organs. This phenomenon has not been thoroughly studied in patients with trauma to date, and an association between BT and postoperative infection has not been well established so far. Methods: MLNs from 36 patients with abdominal trauma were removed during laparotomy and cultured to detect BT. Postoperative infectious complications in these patients were registered, and both phenotypical and molecular typings (through multilocus sequencing) were carried out for microorganisms isolated from MLN and postoperative infection sites. Associations between clinical variables, BT presence, and postoperative infection development were established. Results: BT was detected in 33% of the patients (n = 12). Postoperative infections were present in 22.2% of the patients (n = 8). A significant statistical difference was found between postoperative infections in patients with BT evidence (41.6%), when compared with patients without BT (12.5%; p = 0.047). Bacteria isolated from infection sites were the same as those cultured in MLN in 40% of the cases (n = 2 of 5), allowing us to establish causality between BT and postoperative infection. Conclusions: There is higher risk of BT in trauma patients, and it is associated with a significant increase of postoperative infections. An abdominal trauma index ?10 was found to be associated with the development of BT. This is the first study describing BT among patients with abdominal trauma, where causality is confirmed at molecular level. Copyright © 2011 by Lippincott Williams and Wilkins."
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.relation.ispartofJournal of Trauma - Injury, Infection and Critical Care, Vol.71, No.5 (2011); pp. 1258-1261
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-81455144896&doi=10.1097%2fTA.0b013e318215140e&partnerID=40&md5=912c82c9b034e0411648cf7166c2bf69
dc.sourceinstname:Universidad del Rosario
dc.sourcereponame:Repositorio Institucional EdocUR
dc.titleBacterial translocation in abdominal trauma and postoperative infections
dc.typearticle
dc.subject.keywordAbdominal infection
dc.subject.keywordAbdominal injury
dc.subject.keywordAdolescent
dc.subject.keywordAdult
dc.subject.keywordAged
dc.subject.keywordArticle
dc.subject.keywordBacterial translocation
dc.subject.keywordBacterium culture
dc.subject.keywordBacterium isolation
dc.subject.keywordClinical article
dc.subject.keywordFemale
dc.subject.keywordHigh risk patient
dc.subject.keywordHuman
dc.subject.keywordLaparotomy
dc.subject.keywordMale
dc.subject.keywordMesentery lymph node
dc.subject.keywordMolecular typing
dc.subject.keywordMultilocus sequence typing
dc.subject.keywordNonhuman
dc.subject.keywordPhenotype
dc.subject.keywordPostoperative infection
dc.subject.keywordPriority journal
dc.subject.keywordRespiratory tract infection
dc.subject.keywordSkin infection
dc.subject.keywordWound infection
dc.subject.keywordAbdominal injuries
dc.subject.keywordAdolescent
dc.subject.keywordAdult
dc.subject.keywordAged
dc.subject.keywordAged, 80 and over
dc.subject.keywordBacterial translocation
dc.subject.keywordChi-square distribution
dc.subject.keywordFemale
dc.subject.keywordHumans
dc.subject.keywordMale
dc.subject.keywordMiddle aged
dc.subject.keywordProspective studies
dc.subject.keywordRisk factors
dc.subject.keywordSurgical wound infection
dc.subject.keywordBacterial translocation
dc.subject.keywordLymph nodes
dc.subject.keywordPostoperative infections
dc.subject.keywordSepsis
dc.subject.keywordTrauma
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.type.spaArtículo
dc.rights.accesoAbierto (Texto Completo)
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.identifier.doihttps://doi.org/10.1097/TA.0b013e318215140e
dc.relation.citationEndPage1261
dc.relation.citationIssueNo. 5
dc.relation.citationStartPage1258
dc.relation.citationTitleJournal of Trauma - Injury
dc.relation.citationVolumeVol. 71


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