Common mechanisms of autoimmune diseases (the autoimmune tautology)
Título de la revista
The fact that autoimmune diseases share subphenotypes, physiopathological mechanisms and genetic factors has been called autoimmune tautology, and indicates that they have a common origin. The autoimmune phenotypes vary depending on the target cell and the affected organ, gender, ancestry, trigger factors and age at onset. Ten shared characteristics supporting this logical theory are herein reviewed. © 2012 Elsevier B.V.
Autoimmune disease , Autoimmunity , Clinical feature , Disease severity , Environmental factor , Familial disease , Genetic disorder , Heredity , Human , Immune response , Onset age , Pathophysiology , Phenotype , Review , Risk factor , T lymphocyte , Target cell , Age of onset , Autoimmune diseases , Autoimmunity , Environment , Family , Humans , Phenotype , Sex factors , Autoantibodies , Autoimmune diseases , Autoimmune tautology , Familial autoimmunity , Genetics , Polyautoimmunity