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Interindividual responses to different exercise stimuli among insulin-resistant women

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Autores
Álvarez C.
Ramírez-Vélez R.
Ramírez-Campillo R.
Ito S.
Celis-Morales C.
García-Hermoso A.
Rodriguez-Mañas L.
Lucia A.
Izquierdo M.

Fecha
2018

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Blackwell Munksgaard

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Abstract
We aimed to investigate which among 20 cardiometabolic and performance outcomes do and do not respond to high-intensity interval training (HIT), resistance training (RT), or concurrent training (CT) in insulin-resistant adult women. A secondary aim was to report the training-induced changes and the prevalence of non-responders. Forty-five insulin-resistant adult women were randomly assigned to one of the following 4 groups: HIT (39.2 ± 9.5 years [y]; body mass index [BMI], 29.3 ± 3.3; n = 14), RT (33.9 ± 9.3 y; BMI, 29.4 ± 5.5; n = 8), CT (43.3 ± 8.1 y; BMI, 29.1 ± 2.9; n = 10), and a control group (CG, 40.1 ± 11.4 y; BMI, 28.3 ± 3.5; n = 13). Nine body composition, 3 cardiovascular, 3 metabolic, and 5 performance outcomes were assessed at baseline and after 12 weeks of intervention. Considering all outcomes, the lowest number of total non-responses for one or more variables was found in the RT group, followed by the CT and HIT groups. Individuals in the CG group were classified as non-responders for almost all the variables. Moreover, there were several significant changes in body composition and metabolic parameters, including fasting glucose (HIT: ?5.7, RT ?5.1 mg/d), fasting insulin (HIT: ?0.6, RT ?0.6 ?IU/mL), and HOMA-IR (HIT: ?0.3, RT ?0.4), in addition to improvements in cardiovascular and performance parameters. Also, there were significant differences among groups in the prevalence of non-responders for the variables where a non-response was detected. Overall, the study suggests that independent of the mode of training including volume and frequency, RT has an important ability to reduce the prevalence of non-response to improve the 20 outcomes of health and performance in insulin-resistant adult women. © 2018 John Wiley and Sons A/S. Published by John Wiley and Sons Ltd
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Keywords
Adult , Blood pressure , Body composition , Body mass , Cardiorespiratory fitness , Comparative study , Controlled study , Exercise , Female , Glucose blood level , High intensity interval training , Human , Insulin resistance , Middle aged , Muscle strength , Physiology , Randomized controlled trial , Resistance training , Adult , Blood glucose , Blood pressure , Body composition , Body mass index , Cardiorespiratory fitness , Exercise , Female , High-intensity interval training , Humans , Insulin resistance , Middle aged , Muscle strength , Resistance training , Exercise , Insulin resistance , Non-responders , Responders , Risk factors , Women
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