Show simple item record

dc.creatorAnaya, Juan-Manuel 
dc.creatorShoenfeld, Yehuda 
dc.creatorCervera, Ricard 
dc.date.accessioned2020-08-06T16:20:30Z
dc.date.available2020-08-06T16:20:30Z
dc.date.created2014
dc.identifier.issnISSN: 20900422
dc.identifier.issnEISSN: 2090-0430
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/26034
dc.description.abstractSystemic lupus erythematosus (SLE, lupus) is the prototype of systemic autoimmune disease (AD). Immune system activation in SLE is characterized by exaggerated B-cell and T-cell responses and loss of immune tolerance against self-antigens. Production and defective elimination of antibodies, circulation and tissue deposition of immune complexes, and complement and cytokine activation contribute to clinical manifestations that range from fatigue and joint pain to severe, life-threatening organ damage
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.relation.ispartofAutoimmune diseases, ISSN: 20900422 ; EISSN: 2090-043 (2014); pp.2
dc.relation.urihttp://downloads.hindawi.com/journals/ad/2014/274323.pdf
dc.sourceAutoimmune diseases
dc.titleSystemic lupus erythematosus 2014.
dc.typearticle
dc.publisherHindawi Publishing Corporation
dc.subject.keywordSystemic lupus erythematosus
dc.subject.keywordautoimmune disease
dc.subject.keywordself-antigens
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.type.spaArtículo
dc.rights.accesoAbierto (Texto Completo)
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.identifier.doihttps://doi.org/10.1155/2014/274323
dc.title.TranslatedTitleLupus eritematoso sistémico 2014.
dc.relation.citationStartPage2
dc.relation.citationTitleAutoimmune diseases


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record