Show simple item record

dc.creatorAnaya, Juan-Manuel 
dc.creatorRestrepo, Lucas 
dc.creatorMolina, Jose F 
dc.creatorMantilla, Ruben D 
dc.creatorVargas, Sergio 
dc.creatorVilla, Luis A 
dc.date.accessioned2020-08-19T14:41:50Z
dc.date.available2020-08-19T14:41:50Z
dc.date.created2002
dc.identifier.issnISSN: 1076-1608
dc.identifier.issnEISSN: 1536-7355
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/27346
dc.description.abstractCentral nervous system (CNS) involvement in primary Sjogren's syndrome (SS) is poorly understood, and its frequency as well as its manifestations are subjects of controversy. The current study was undertaken to determine the prevalence and the clinical and immunogenetic characteristics of CNS compromise in a well defined group of patients with primary SS. In this retrospective study, patients fulfilled the European classification criteria. Among 120 patients with primary SS, 3 (2.5%) had CNS compromise (multiple sclerosis-like illness, complicated migraine, and optic neuritis with epilepsy). The CNS involvement coincided with the onset of sicca symptoms in 1 case. All 3 patients carried the human leukocyte antigen (HLA) DQB1*0303 allele and tested positive for anti-Ro antibodies, but not for anti-cardiolipin antibodies. Although rare, CNS compromise in primary SS can be the presenting manifestation of the disease in a few cases, and may be severe and varied.
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.relation.ispartofJournal of Clinical Rheumatology, ISSN: 1076-1608; EISSN: 1536-7355, Vol.8, No.4 (2002); pp. 189-196
dc.relation.urihttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=prem&NEWS=N&AN=17041358
dc.sourceJournal of Clinical Rheumatology
dc.titleCentral nervous system compromise in primary Sjogren's syndrome.
dc.typearticle
dc.publisherCanadian Rheumatology Association
dc.subject.keywordSjögren’s syndrome
dc.subject.keywordCentral nervous system
dc.subject.keywordMultiple sclerosis
dc.subject.keywordMigraine
dc.subject.keywordHuman leukocyte antigen
dc.subject.keywordColombia
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.type.spaArtículo
dc.rights.accesoRestringido (Acceso a grupos específicos)
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.title.TranslatedTitleCompromiso del sistema nervioso central en el síndrome de Sjogren primario.
dc.relation.citationEndPage196
dc.relation.citationIssueNo. 4
dc.relation.citationStartPage189
dc.relation.citationTitleJournal of Clinical Rheumatology
dc.relation.citationVolumeVol. 8


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record