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dc.creatorGarcia Salazar, Luisa Fernanda 
dc.creatorLopes dos Santos, Gabriela 
dc.creatorPavao, Silvia Letícia 
dc.creatorCicuto Ferreira Rocha, Nelci Adriana 
dc.creatorde Russo, Thiago Luiz 
dc.date.accessioned2020-08-28T15:48:13Z
dc.date.available2020-08-28T15:48:13Z
dc.date.created2014-09-02
dc.identifier.issnISSN: 1751-8423
dc.identifier.issnEISSN: 1751-8431
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/28451
dc.description.abstractObjective: This article aimed to review the literature to verify the effect of botulinum toxin type A (BTX-A) on the intrinsic properties of spastic muscles and functionality in children with cerebral palsy (CP). Methods: A literature search was conducted in the following databases: CINAHL, SCOPUS, Web of Science and PubMed. Database searches were limited to the period from January 1993 to March 2014. Results: A total of 2182 papers were identified, and 17 met the inclusion criteria. Only one study analyzed the effect of the toxin on muscle intrinsic properties and others analyzed the effect on functionality. Conclusion: BTX-A application demonstrated no changes in the passive stiffness of spastic muscle. In relation to functional level, the evidence of BTX-A effect was controversial. These studies showed methodological quality limitations that restrict the interpretation of the results for the entire CP population, which justifies the need for further randomized controlled trials.
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.relation.ispartofDevelopmental Neurorehabilitation, ISSN: 1751-8423;EISSN: 1751-8431, Vol. 18, No. 1 (2015); pp. 1-14
dc.relation.urihttps://www.tandfonline.com/doi/abs/10.3109/17518423.2014.948640
dc.sourceDevelopmental Neurorehabilitation
dc.titleIntrinsic properties and functional changes in spastic muscle after application of BTX-A in children with cerebral palsy: systematic review
dc.typearticle
dc.publisherTaylor & Francis
dc.subject.keywordBotulinum toxin
dc.subject.keywordFunctionality
dc.subject.keywordMotor developmental
dc.subject.keywordMuscle spasticity
dc.subject.keywordRehabilitation
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.type.spaArtículo
dc.rights.accesoRestringido (Acceso a grupos específicos)
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.identifier.doihttps://doi.org/10.3109/17518423.2014.948640
dc.title.TranslatedTitlePropiedades intrínsecas y cambios funcionales en el músculo espástico después de la aplicación de BTX-A en niños con parálisis cerebral: revisión sistemática
dc.relation.citationEndPage14
dc.relation.citationIssueNo. 1
dc.relation.citationStartPage1
dc.relation.citationTitleDevelopmental Neurorehabilitation
dc.relation.citationVolumeVol. 18


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