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dc.creatorGarcia Salazar, Luisa Fernanda 
dc.creatorLopes dos Santos, Gabriela 
dc.creatorPavao, Silvia Letícia 
dc.creatorCicuto Ferreira Rocha, Nelci Adriana 
dc.creatorde Russo, Thiago Luiz
dc.identifier.issnISSN: 1751-8423
dc.identifier.issnEISSN: 1751-8431
dc.description.abstractObjective: This article aimed to review the literature to verify the effect of botulinum toxin type A (BTX-A) on the intrinsic properties of spastic muscles and functionality in children with cerebral palsy (CP). Methods: A literature search was conducted in the following databases: CINAHL, SCOPUS, Web of Science and PubMed. Database searches were limited to the period from January 1993 to March 2014. Results: A total of 2182 papers were identified, and 17 met the inclusion criteria. Only one study analyzed the effect of the toxin on muscle intrinsic properties and others analyzed the effect on functionality. Conclusion: BTX-A application demonstrated no changes in the passive stiffness of spastic muscle. In relation to functional level, the evidence of BTX-A effect was controversial. These studies showed methodological quality limitations that restrict the interpretation of the results for the entire CP population, which justifies the need for further randomized controlled trials.
dc.relation.ispartofDevelopmental Neurorehabilitation, ISSN: 1751-8423;EISSN: 1751-8431, Vol. 18, No. 1 (2015); pp. 1-14
dc.sourceDevelopmental Neurorehabilitation
dc.titleIntrinsic properties and functional changes in spastic muscle after application of BTX-A in children with cerebral palsy: systematic review
dc.publisherTaylor & Francis
dc.subject.keywordBotulinum toxin
dc.subject.keywordMotor developmental
dc.subject.keywordMuscle spasticity
dc.rights.accesoRestringido (Acceso a grupos específicos)
dc.title.TranslatedTitlePropiedades intrínsecas y cambios funcionales en el músculo espástico después de la aplicación de BTX-A en niños con parálisis cerebral: revisión sistemática
dc.relation.citationIssueNo. 1
dc.relation.citationTitleDevelopmental Neurorehabilitation
dc.relation.citationVolumeVol. 18

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