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dc.contributor.advisorZuñiga Rodriguez, Eduardo Alfonso 
dc.contributor.advisorMolano-González, Nicolas 
dc.creatorCastellanos de la Hoz, Juan Camilo 
dc.creatorGarcia Habeych, Jose Mauricio 
dc.date.accessioned2021-07-28T20:55:00Z
dc.date.available2021-07-28T20:55:00Z
dc.date.created2021-07-13
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/31937
dc.descriptionIntroducción. La lesión renal aguda (LRA) se caracteriza por una disminución abrupta de la función renal que desencadena graves consecuencias a largo plazo. La predicción del desarrollo de LRA en la unidad de cuidados intensivos (UCI) es limitada. Por lo tanto, se caracterizaron tres herramientas de predicción para LRA. Metodología. Estudio observacional retrospectivo, en adultos ingresados a UCI. Excluyendo pacientes en terapia de reemplazo renal previo al ingreso, LRA en el momento del ingreso, antecedente de trasplante renal, remitidos desde otra UCI o estancia < 48 horas. Los datos se recogieron durante una semana después del ingreso a UCI y se aplicaron a las herramientas de angina renal (Cruz et al., Índice de angina renal (RAI) y AKIpredictor). La LRA se definió con la clasificación KDIGO. Resultados. Ingresaron 1625 pacientes a UCI y se incluyeron 490 pacientes. 160 (32,6%) pacientes presentaron LRA. El puntaje de Cruz et al. presentó una sensibilidad del 92,8% y una especificidad del 56,6%, con una razón de verosimilitud negativa (-LR) de 0,13. El RAI y AKIpredictor presentaron un área bajo la curva de 0,66 (IC 95% 0,6-0,73) y 0,66 (IC 95% 0,59-0,73) respectivamente, con una -LR de 0,73 (IC 95% 0,6-0,89) y 0,4 (IC del 95%:0,17-0,77) respectivamente. Conclusiones. La caracterización de las herramientas de angina renal mostró que su utilidad radica en determinar qué pacientes tienen bajo riesgo y requieren menos intervenciones para la prevención de la LRA.
dc.description.abstractIntroduction. Acute Kidney Injury (AKI) is characterized by an abrupt decrease in kidney function that triggers severe long term consequences after the event. Prediction of the development of AKI in the (ICU) is limited. Therefore, three prediction tools for AKI were characterized. Methodology. Retrospective observational study, developed from January 31 to September 30, 2020, in adults admitted to the ICU. Patients on renal replacement therapy prior to admission, AKI at the time of admission, history of kidney transplantation, referred from another ICU or a stay of < 48 hours were excluded. Data was collected for a week after admission to intensive care and applied to the renal angina tools (Cruz et al., renal angina index and AKIpredictor). AKI was defined with the KDIGO classification. Results. 1625 patients were admitted to the ICU, of which 490 patients were included. 160 (32.6%) patients presented AKI. The Cruz et al. score presented a sensitivity of 92.8% and specificity of 56.6%, with a negative likelihood ratio (-LR) of 0.13. The renal angina index and AKIpredictor presented an area under the curve of 0.66 (95% CI 0.6-0.73) and 0.66 (95% CI 0.59-0.73) respectively, with a -LR of 0.73 (95% CI 0.6-0.89) and 0.4 (95% CI 0.17-0.77) respectively. Conclusions. The characterization of renal angina tools showed that their usefulness lies in determining which patients are at low risk and require fewer interventions for the prevention of AKI.
dc.format.extent109 pp.
dc.format.mimetypeapplication/pdf
dc.language.isospa
dc.subjectAnálisis de herramientas de predicción de Lesión Renal Aguda (LRA)
dc.subjectBiomarcadores para el diagnóstico de Lesión Renal Aguda (LRA)
dc.subjectAngina renal (Metodología clínica para estratificación de riesgo de LRA)
dc.subjectEstrategias de evolución de riesgos de LRA en pacientes internados en UCI
dc.subject.ddcIncidencia & prevención de la enfermedad 
dc.titleAngina renal. Caracterización de las herramientas de predicción de lesión renal aguda en cuidado intensivo adultos
dc.typemasterThesis
dc.publisherUniversidad del Rosario
dc.creator.degreeEspecialista en Nefrología
dc.publisher.programEspecialización en Nefrología
dc.publisher.departmentEscuela de Medicina y Ciencias de la Salud
dc.subject.keywordAnalysis of Acute Kidney Injury (AKI) prediction tools
dc.subject.keywordBiomarkers for the diagnosis of Acute Kidney Injury (AKI)
dc.subject.keywordRenal Angina (Clinical Methodology for AKI Risk Stratification)
dc.subject.keywordStrategies for the evolution of AKI risk in patients admitted to intensive care
dc.subject.keywordRisk evolution strategies for AKI in patients admitted to the intensive care
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.type.spaTesis de maestría
dc.rights.accesoAbierto (Texto Completo)
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
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dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.
dc.type.documentRevisión sistemática
dc.creator.degreetypeFull time
dc.title.TranslatedTitleRenal angina. Characterization of the tools prediction of acute kidney injury in intensive care adults
dc.source.instnameUniversidad del Rosario
dc.source.reponameRepositorio Institucional EdocUR
dc.creator.degreeLevelMaestría


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