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dc.contributor.advisorMateus Arbelaez, Heidi Eliana 
dc.contributor.advisorFonseca-Mendoza, Dora Janeth 
dc.creatorAmado González, Paula 
dc.date.accessioned2012-07-19T12:29:20Z
dc.date.available2012-07-19T12:29:20Z
dc.date.created2011-12-15
dc.date.issued2011
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/3616
dc.descriptionLa Fibrosis Quística es la enfermedad autosómica recesiva mas frecuente en caucásicos. En Colombia no se conoce la incidencia de la enfermedad, pero investigaciones del grupo de la Universidad del Rosario indican que podría ser relativamente alta. Objetivo: Determinar la incidencia de afectados por Fibrosis Quística en una muestra de recién nacidos de la ciudad de Bogotá. Metodología: Se analizan 8.297 muestras de sangre de cordón umbilical y se comparan tres protocolos de tamizaje neonatal: TIR/TIR, TIR/DNA y TIR/DNA/TIR. Resultados: El presente trabajo muestra una incidencia de 1 en 8.297 afectados en la muestra analizada. Conclusiones: Dada la relativamente alta incidencia demostrada en Bogotá, se justifica la implementación de Tamizaje Neonatal para Fibrosis Quística en Colombia.
dc.description.abstractCystic Fibrosis is the most common autosomic recessive disease in caucasic population. The incidence in Colombia is still unknown, but previous studies at Universidad del Rosario have shown that it is relatively high . Objective: To establish the incidence of the disease on a newborn population from Bogota. Methods: 8.297 cordblood samples were analyzed. Three neonatal screening test protocols were compared: IRT/IRT, IRT/DNA and IRT/DNA/IRT. Results: The present study showed an incidence of 1 in 8.297 for Cystic Fibrosis in the population. Conclusions: Given the relatively high incidence observed in Bogota, Cystic Fibrosis Neonatal screening is advisable for the colombian population.
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dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.sourceinstname:Universidad del Rosario
dc.sourcereponame:Repositorio Institucional EdocUR
dc.subjectFibrosis quística
dc.subjectTamizaje neonatal
dc.subjectTripsinogeno
dc.subjectSangre de cordón umbilical
dc.subject.lembFibrosis quística::Investigaciones
dc.subject.lembExámenes médicos::Investigaciones
dc.subject.lembEnfermedades de los niños recién nacidos::Investigaciones
dc.titleTamizaje neonatal para fibrosis quística en una muestra de la ciudad de Bogotá
dc.typemasterThesis
dc.publisherUniversidad del Rosario
dc.creator.degreeMagíster en Ciencias con Énfasis en Genética Humana
dc.publisher.programMaestría en Ciencias con Énfasis en Genética Humana
dc.publisher.departmentFacultad de medicina
dc.subject.keywordCystic fibrosis
dc.subject.keywordNeonatal Screening
dc.subject.keywordTripsinogen
dc.subject.keywordCord blood
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.type.spaTesis de maestría
dc.rights.accesoAbierto (Texto completo)
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
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