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dc.contributor.advisorFlórez Betancourt, Clara Jimena 
dc.creatorPérez Pachón, Karen Johanna 
dc.date.accessioned2013-02-01T22:21:02Z
dc.date.available2013-02-01T22:21:02Z
dc.date.created2013-01-23
dc.date.issued2013
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/4163
dc.descriptionIntroducción: La preeclampsia severa es una de las principales patologías que afectan a las mujeres embarazadas, sus complicaciones tienen un alto impacto en la salud del binomio madre-hijo. Materiales y métodos: Se realizo una serie de casos, durante un periodo de 1 año se revisaron las historias clínicas de las pacientes que ingresaron a la unidad de cuidado intensivo obstétrico de la Clínica Orquídeas, con diagnóstico de preeclampsia severa. Se describieron los datos demográficos y las complicaciones. Se realizó análisis univariado con las variables de interés y se calcularon diferencias significativas por medio del test exacto de Fisher. Resultados: Se registraron 196 pacientes con preeclampsia severa en el periodo de estudio. Las complicaciones mas frecuentes fueron síndrome HELLP (30,6%), insuficiencia renal aguda (16,3%) y edema pulmonar (10,2%); el ingreso de las pacientes con preeclampsia severa a la UCIO en embarazo aumenta el riesgo de sufrir complicaciones. El síndrome de HELLP se presento con mayor frecuencia en pacientes que realizaron 6 o mas controles prenatales (p=0.066). Discusión: Los resultados evidencian una prevalencia de preeclampsia severa mayor que la observada por otros autores, probablemente por ser una UCI exclusivamente obstétrica. Las complicaciones mas frecuentes son concordantes con otros estudios publicados. El mayor riesgo de complicaciones asociadas en pacientes que ingresan embarazadas a la UCIO podría estar en relación a la severidad de la patología. Se requieren estudios analíticos para establecer asociaciones entre cada una de las complicaciones y sus factores condicionantes.
dc.description.abstractIntroduction: Severe preeclampsia is one of the major diseases affecting pregnant women, its complications have high impact on the health of mothers and children. Methods: We performed a cross-sectional descriptive study, over a period of 1 year. We included all patients admitted to the intensive care unit of the Clinica Orquídeas with severe preeclampsia. We describe the demographics and complications. Univariate analysis was performed with the variables of interest and significant differences were calculated using the Fisher exact test. Results: There were 196 patients with severe preeclampsia during the study period. The most frequent complications were HELLP syndrome, acute renal failure and pulmonary edema. The entry of patients with severe preeclampsia to UCIO in pregnancy increases the risk of complications. The HELLP syndrome were most frecuent in patients with 6 or more prenatal care controls (p=0.066). Discussion: The results show a higher prevalence of severe preeclampsia than observed by other authors, probably in relation to a reference obstetric ICU. The most frequent complications are HELLP syndrome, pulmonary edema and renal failure, same as other published studies. The increased risk of associated complications in pregnant patients admitted to ICU could be related to the severity of the pathology. Analytical studies are required to establish associations between each of the complications and associated factors.
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dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.subjectPreeclampsia severa
dc.subjectComplicaciones
dc.subject.lembComplicaciones del embarazo
dc.subject.lembPreeclampsia
dc.subject.lembObstetricia::Investigaciones
dc.titleComplicaciones de la preeclampsia severa y su relación con variables demográficas y obstétricas
dc.typemasterThesis
dc.publisherUniversidad del Rosario
dc.creator.degreeEspecialista en Ginecología y Obstericia
dc.publisher.programEspecialización en Ginecología y Obstericia
dc.publisher.departmentFacultad de Medicina
dc.subject.keywordSevere preeclampsia
dc.subject.keywordComplication
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.type.spaTrabajo de grado
dc.rights.accesoAbierto (Texto completo)
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.source.bibliographicCitation1. Curiel E., Prieto M., Muñoz J., Ruiz de Elvira M., Galeas J., Quesada G.. Análisis de la morbimortalidad materna de las pacientes con preeclampsia grave, eclampsia y síndrome HELLP que ingresan en una Unidad de Cuidados Intensivos gineco-obstétrica. Medicina Intensiva. 2011; 35(8):478-483
dc.source.bibliographicCitation2. Steegers EA, Von Dadelszen P, Duvekot JJ, Pijnenborg R. Pre-eclampsia. Lancet, 2010, 21;376(9741):631–44.
dc.source.bibliographicCitation3. Tesis de Grado UNAL. ALZATE Andrea, Bracho Alcides, Fajardo Luisa. Análisis mortalidad materna en Bogotá en los años 2006, 2007 y 2008. Tesis (Especialista en Obstetricia y Ginecología). Bogotá, Colombia. Universidad Nacional de Colombia, Facultad de Medicina, 2010. 251h.
dc.source.bibliographicCitation4. WHO: Recommendations for Prevention and treatment of pre-eclampsia and eclampsia, Geneva,World Health Organization, 2011.
dc.source.bibliographicCitation5. Dildy G., A. Iii. Y Belfort M., A.. Complications of pre-eclampsia. EnLYALL, F. y BELFORT, M.. Pre-eclampsia Etiology and ClinicalPractice. New York, Cambridge UniversityPress, 2007. P 406
dc.source.bibliographicCitation6. Report of the National High Blood Pressure Education Program Working Groupon High Blood Pressure in Pregnancy. American Journal Obstetrics Gynecology 2000; 183: S1–S22.
dc.source.bibliographicCitation7. Anonymous, (2000). National High Blood Pressure Education Program Working Group report on high blood pressure in pregnancy. NIH Publication No. 00-3029
dc.source.bibliographicCitation8. Anonymous. (2002). American College of Obstetricians and Gynecologists. Diagnosis and management of preeclampsia and eclampsia. ACOG Practice Bulletin No. 33. Obstet. Gynecol., 99, 159_67.
dc.source.bibliographicCitation9. Sibai B., Stella C.. Diagnosis and management of atypical pre-eclampsia-eclampsia. American Journal of Obstetrics Gynecology 2009; 200: 481. e1–481.e7
dc.source.bibliographicCitation10. JOGC, 2008. Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy. Journal of Obstetrics and Gynaecology Canada, volume 30, numéro 3 March 2008, Supplement 1.
dc.source.bibliographicCitation11. Weinstein, L.. Syndrome of hemolysis, elevated liver enzymes, and low platelet count: a severe consequence of hypertension in pregnancy. American Journal of Obstetrics and Gynecology. 1982, 142, 159-67
dc.source.bibliographicCitation12. Vigil P., Montufar C., Smith A.. Pregnancy and Severe Chronic Hypertension: Maternal Outcome. HYPERTENSION IN PREGNANCY, 2004, Vol. 23, No. 3, pp. 285–293.
dc.source.bibliographicCitation13. WHO: The World Health Report 2005: Make every mother and child count. Geneva, World Health Organization, 2005
dc.source.bibliographicCitation14. Zhang J., Meikle S., Trumble A.,. Severe Maternal Morbidity Associated with Hypertensive Disorders in Pregnancy in the United States. Hypertension in Pregnancy, Vol. 22, No. 2, pp. 203–212, 2003.
dc.source.bibliographicCitation15. Berg CJ, Atrash HK, Koonin LM, Tucker M. Pregnancy-related mortality in the United States, 1987–1990. Obstet Gynecol 1996; 88:161–167
dc.source.bibliographicCitation16. Khan KS, Wojdyla D, Say L et al. WHO analysis of causes of maternal death: a systematic review. Lancet 2006; 367: 1066–1074
dc.source.bibliographicCitation17. CDC. Health, United States, 2008. Hyattsville, MD: National Center for Health Statistics; 2008
dc.source.bibliographicCitation18. Duley L: Maternal mortality associated with hypertensive disorders of pregnancy in Africa, Asia, Latin America and the Caribbean. British Journal Obstetrics and Gynaecology 99:547-553, 1992
dc.source.bibliographicCitation19. American College of Obstetricians and Gynecologists. Hypertension in pregnancy. ACOG Tech Bull 1996; 219:1–8
dc.source.bibliographicCitation20. Salazar J., Triana J., Prieto F.. Caracterización de los trastornos hipertensivos del embarazo. Revista Colombiana de Obstetricia y Ginecología, vol. 55, núm. 4, 2004, pp. 279-286
dc.source.bibliographicCitation21. Hutcheon J., Lisonkova S., Joseph K.. Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy. Best Practice & Research Clinical Obstetrics and Gynaecology, 25(2011) 391–403.
dc.source.bibliographicCitation22. World Health Organization international collaborative study of hypertensive disorders of pregnancy. Geographic variation in the incidence of hypertension in pregnancy. American Journal of Obstetrics and Gynecology, 158:80-83, 1988.
dc.source.bibliographicCitation23. Kaaja R, Kinnunen T, Luoto R. Regional differences in the prevalence of pre-eclampsia in relation to the risk factors for coronary artery disease in women in Finland. European Heart Journal. 2005;26:44-50
dc.source.bibliographicCitation24. Tricia T. Gilbert, MD, John C. Smulian, MD, MPH, Andrew A. Martin, MD. Obstetric Admissions to the Intensive Care Unit: Outcomes and Severity of Illness. Obstet Gynecol 2003;102:897–903. © 2003 American College of Obstetricians and Gynecologists
dc.source.bibliographicCitation25. Neal g. Mahutte, md, lynn murphy-kaulbeck, md, quynh le, md. Obstetric Admissions to the Intensive Care Unit. Obstet Gynecol 1999;94:263– 6.
dc.source.bibliographicCitation26. H. M. Mirghani, M. Hamed,* M. Ezimokhai, D. S. L. Weerasinghe. Pregnancy-related admissions to the intensive care unit. International Journal of Obstetric Anesthesia (2004) 13, 82–85
dc.source.bibliographicCitation27. U. V. Okafor, U. Aniebue. Admission pattern and outcome in critical care obstetric patients. International Journal of Obstetric Anesthesia (2004) 13, 164–166.
dc.source.bibliographicCitation28. O. Demirkiran, Y. Dikmen, T. Utku, S. Urkmez. Critically ill obstetric patients in the intensive care unit. International Journal of Obstetric Anesthesia (2003) 12, 266–270
dc.source.bibliographicCitation29. Rojas JA., Miranda JE., Ramos E. y Fernández JC.. Cuidado crítico en la paciente obstétrica. Complicaciones, intervenciones y desenlace materno fetal. Clínica e Investigación en Ginecología y Obstetricia, 2011;38(2):44—49.
dc.source.bibliographicCitation30. Mogollón SP., Salcedo F., Ramos E.. Resultados materno perinatales de la preeclampsia lejos del término. Clínica de Maternidad Rafael Calvo. Cartagena. Colombia. Revista Ciencias Biomédicas, 2011; 2 (2): 262-269.
dc.source.bibliographicCitation31. American College of Obstetricians and Gynecologists. Diagnosis and management of Preeclampsia and Eclampsia. ACOG practice bulletin, Number 33, January 2002
dc.source.bibliographicCitation32. Meza RA., Pareja M., Navas F.. Síndrome HELLP, una patología del cuidado crítico. Acta Colombiana de Cuidado Intensivo, 2010; 10(2): 111-120.
dc.source.bibliographicCitation33. Audibert F, Friedman SA, Frangieh AY, Sibai BM.. Clinical utility of strict diagnostic criteria for the HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome. American Journal of Obstetrics and Gynecology,1996, 175:460-464.
dc.source.bibliographicCitation34. Sibai BM.. The HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): much a do about nothing?. American Journal of Obstetrics and Gynecology, 1990, 162:311-316.
dc.source.bibliographicCitation35. Barton JR, Sibai BM.. Diagnosis and management of hemolysis, elevated liver enzymes, and low platelets syndrome. Clinics in Perinatology,2004, 31:807-33.
dc.source.bibliographicCitation36. Martin JN., Blake PG., Lowry SL., Perry KG., Files JC., Morrison JC.. Pregnancy complicated by preeclampsia-eclampsia with the syndrome of hemolysis, elevated liver enzymes and low platelet count: How rapid is postpartum recovery ?. Obstetrics and Gynecology, 1990;76:737-41.
dc.source.bibliographicCitation37. AETIOLOGY, MATERNAL AND FOETAL OUTCOME IN 60 CASES OF OBSTETRICAL ACUTE RENAL FAILURE. Muhammad Abdul MaboodKhalil, AmerAzhar, NisarAnwar, Aminullah, Najm-ud-Din,Raj Wali.
dc.source.bibliographicCitation38. Pre-eclampsia and theKidneyFadi G. Mirza, MD, and Kirsten Lawrence Cleary, MD
dc.source.bibliographicCitation39. Parkash J, Kumar H, Sinha DK, Kedalaya PG, Pandey LK, Srivastva PK, et al. Acute renal failure in pregnancy in a developing country: twenty years of experience. Ren Fail 2006;28(4):309–13.
dc.source.bibliographicCitation40. Creasy RK, Resnick R, Iams J, et al: Maternal-fetal medicine: Principles 
and practice (ed 6), in Philadelphia, PA, WB Saunders, 2009
dc.source.bibliographicCitation41. Moran P, Baylis PH, Lindheimer MD, et al: Glomerular ultrafiltration in normal and preeclamptic pregnancy. J Am SocNephrol 14:648-652, 
2003
dc.source.bibliographicCitation42. Thadhani R, Pascual M, Bonventre J: Acute renal failure. N Engl J Med1996; 334: 1448 –1460
dc.source.bibliographicCitation43. Bouman C, Kellum JA, Lamiere N, et al: Definitionf or Acute Renal Failure. In: Acute Dialysis Quality Initiative: 2nd International Consensus Conference, Workgroup I, 2003
dc.source.bibliographicCitation44. Ghada Bourjeily, MD, Margaret Miller, MD. Obstetric Disorders in the ICU. ClinChestMed 30 (2009) 89–102
dc.source.bibliographicCitation45. Sibai BM, Mabie BC, Harvey CJ, et al. Pulmonary edema in severe preeclampsia-eclampsia: analysis of thirty-seven consecutive cases
Am J ObstetGyne- col. 1987;156:1174-9. 25. 

dc.source.bibliographicCitation46. Saketh R. Guntupalli, MD; JaySteingrub, MD. Hepatic disease and pregnancy: An overview of diagnosis and management. CritCareMed 2005 Vol. 33, No. 10 (Suppl.)
dc.source.bibliographicCitation47. John R. Barton, MD,* and Baha M. Sibai, MD†.Gastrointestinal Complications of Pre-eclampsia. SeminPerinatol 33:179-188 © 2009
dc.source.bibliographicCitation48. S.K. Mishra, R.R. Bhat, K. Sudeep, M. Nagappa, A. swain, A. Badhe: PRES (Posterior Reversible Encephalopathy Syndrome) and Eclampsia:-Review. The Internet Journal of Neurology. 2009 Volume 12 Number 1. DOI: 10.5580/c6
dc.source.bibliographicCitation49. Judy hinchey, m.d., claudia chaves, m.d., barbara appignani, m.d., joan breen, m.d., “A reversible posterior leuko encephalopathy syndrome. N Engl J Med 1996;334:494-500
dc.source.bibliographicCitation50. David R. Hall, MBChB, MMed, MD. Abruptio Placentae and
Disseminated Intravascular Coagulopathy. SeminPerinatol 33:189-195 © 2009
dc.source.bibliographicCitation51. Aali BS, Ghafoorian J, Mohamed- Alizadeh S. Severe preeclamp- sia and eclampsia in Kerman, Iran: complication and outcomes. MedSciMonit. 2004;10:163—7.
dc.source.bibliographicCitation52. Villar J, Carroli G, Wojdyla D et al. Pre-eclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions? Am J ObstetGynecol 2006; 194: 921–931.
dc.source.bibliographicCitation53. Basso O, Rasmussen S, Weinberg CR et al. Trends in fetal and infant survival following pre-eclampsia. JAMA 2006; 296: 1357–1362.
dc.source.bibliographicCitation54. Ananth CV, Savitz DA, Luther ER et al. Pre-eclampsia and preterm birth subtypes in Nova Scotia, 1986 to 1992. Am J Perinatol 1997; 14: 17–23.
dc.source.bibliographicCitation55. Xiong X, Demianczuk NN, Buekens P & Saunders LD. Association of pre-eclampsia with high birth weightf orage. Am J ObstetGynecol 2000; 183: 148–155.
dc.source.bibliographicCitation56. Baldwin KJ., Leighton NA., Kilby MD., Wyldes M., Churchill D., Johanson RB.. The west midlands “severe hypertensive illness in pregnancy” (ship) audit. hypertension in pregnancy, 2001, 20(3), 257–268
dc.source.bibliographicCitation57. Monsalve G., Martínez C., Gallo T., González MV., Arango G, Upegui A. Y cols.. Cuidado crítico materno: desenlaces y características de los pacientes de una unidad obstétrica combinada de alta dependencia en Medellín, Colombia. Revista Colombiana Anestesiología. Mayo - julio 2011. Vol. 39 - No. 2: 190-205
dc.source.bibliographicCitation58. Roiz J, Jimenez J. Preeclampsia-eclampsia. Experiencia en el centro médico nacional de Torreón. GinecolObstetMex. 2001; 69:341—5.
dc.source.bibliographicCitation59. Drakeley AJ, Le Roux PA, Anthony J, et al. Acute renal failure complicating severe preeclampsia requiring admission to an obstetric intensive care unit. Am J ObstetGynecol. 2002;186:253-6
dc.source.bibliographicCitation60. Alanis MC, Robinson CJ, Hulsey TC, Ebeling M, Johnson DD. Early-onset severe preeclampsia: induction of labor vs elective cesarean delivery and neonatal outcomes. Am J ObstetGynecol 2008:199:262.e1-6.
dc.source.bibliographicCitation61. Wessel G, Rep A, de Vries J, Bonsel GJ, Hans W. Prediction of maternal complications and adverse infant outcome at admission for temporizing management of early-on set severe hypertensive disorders of pregnancy. Am J Obstet Gynecol 2006:195;495-503.
dc.source.bibliographicCitation62. Mesa CM., Mesa LE, Jimeno MP., Mora AM. Factores de riesgo para la preeclampsia severa y temprana en el Hospital general de Medellin 1999-2000. CES Medicina. 2001:15 (1) ;20-8
dc.source.bibliographicCitation63. Barreto S. Preeclampsia severa, eclampsia y sindrome de hellp: características maternas y resultados neonatales. Unidad de cuidados intensivos maternos Instituto materno perinatal. 
Lima, Peru 1999-2000 Revista Instituto Materno Perinatal. Lima, Peru 2002:17-23
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dc.rights.ccAtribución-NoComercial-SinDerivadas 2.5 Colombia
dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma.
dc.identifier.doihttps://doi.org/10.48713/10336_4163
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR


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