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dc.creatorQuintero-Ronderos, Paula 
dc.creatorMontoya-Ortiz, Gladis 
dc.date.accessioned2014-08-11T19:52:24Z
dc.date.available2014-08-11T19:52:24Z
dc.date.created2012
dc.date.issued2012 
dc.identifier.issnISSN:2090-0430
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/8777
dc.description.abstractEpigenetics is defined as the study of all inheritable and potentially reversible changes in genome function that do not alter the nucleotide sequence within the DNA. Epigenetic mechanisms such as DNA methylation, histone modification, nucleosome positioning, and microRNAs (miRNAs) are essential to carry out key functions in the regulation of gene expression. Therefore, the epigenetic mechanisms are a window to understanding the possible mechanisms involved in the pathogenesis of complex diseases such as autoimmune diseases. It is noteworthy that autoimmune diseases do not have the same epidemiology, pathology, or symptoms but do have a common origin that can be explained by the sharing of immunogenetic mechanisms. Currently, epigenetic research is looking for disruption in one or more epigenetic mechanisms to provide new insights into autoimmune diseases. The identification of cell-specific targets of epigenetic deregulation will serve us as clinical markers for diagnosis, disease progression, and therapy approaches.
dc.format.mediumRecurso electrónico
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.relation.ispartofAutoimmune Diseases, ISSN 2090-04-30, 2012
dc.sourcereponame:Repositorio Institucional EdocUR
dc.sourceinstname:Universidad del Rosario
dc.subject.ddcEnfermedades 
dc.titleEpigenetics and autoimmune diseases
dc.typearticle
dc.audienceComunidad Rosarista
dc.publisherUniversidad del Rosario
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.subject.decsGenética
dc.subject.decsRepresión Epigenética
dc.subject.decsEnfermedades autoinmunes
dc.subject.decsInmunología
dc.type.spaArtículo
dc.rights.accesoAbierto (Texto completo)
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.format.tipoDocumento
dc.rights.licenciaEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma.
dc.creator.googleQuintero-Ronderos, Paula
dc.creator.googleMontoya-Ortiz, Gladis


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