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Anti-cyclic citrullinated peptide antibodies in patients with primary Sjögren's syndrome

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dc.creatorTobón, G Jspa
dc.creatorCorrea, P Aspa
dc.creatorAnaya, Juan-Manuelspa
dc.date.accessioned2020-08-19T14:41:07Z
dc.date.available2020-08-19T14:41:07Z
dc.date.created2005-05spa
dc.description.abstractPrimary Sjögren’s syndrome (pSS) is an autoimmune late onset disease characterised mainly by sicca symptoms. Lymphocytic infiltrate of the minor salivary glands and the presence of autoantibodies are the hallmarks of disease.1 The spectrum of pSS extends from an organ-specific autoimmune disorder (autoimmune exocrinopathy) to a systemic process that may involve the musculoskeletal system, leading to arthralgias and arthritis. In the latter case differential diagnosis with other autoimmune diseases like rheumatoid arthritis (RA) is a challenge. In these situations, specific antibodies may be useful for making a correct diagnosis and, consequently, guide treatment. Anti-cyclic citrullinated peptide (anti-CCP) antibodies have been shown to be a specific marker for the diagnosis of RA.2 They bind to determinants rich in the unusual amino acid, citrulline, generated by deamination of arginine.3 We have read the recent article by Gottenberg et al,4 in which a 7.5% prevalence of anti-CCP antibodies in 134 French patients with pSS was reported. Here, we describe a similar experience in Colombian patients with pSS.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttp://dx.doi.org/10.1136/ard.2004.029603
dc.identifier.issnISSN: 0003-4967
dc.identifier.issnEISSN: 1468-2060
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/27139
dc.language.isoengspa
dc.publisherEuropean League Against Rheumatismspa
dc.publisherBMJ Publishingspa
dc.relation.citationEndPage792
dc.relation.citationIssueNo. 5
dc.relation.citationStartPage791
dc.relation.citationTitleAnnals of the Rheumatic Diseases
dc.relation.citationVolumeVol. 64
dc.relation.ispartofAnnals of the Rheumatic Diseases, ISSN: 0003-4967;EISSN: 1468-2060, Vol.64, No.5 (2005); pp. 791-792spa
dc.relation.urihttps://ard.bmj.com/content/annrheumdis/64/5/791.full.pdfspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.sourceAnnals of the Rheumatic Diseasesspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordArthritisspa
dc.subject.keywordrheumatoid immunologyspa
dc.subject.keywordSjogren's Syndrome immunologyspa
dc.subject.keywordHumansspa
dc.subject.keywordAutoantibodies analysisspa
dc.titleAnti-cyclic citrullinated peptide antibodies in patients with primary Sjögren's syndromespa
dc.title.TranslatedTitleAnticuerpos anti-péptido cíclico citrulinado en pacientes con síndrome de Sjögren primariospa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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