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Exercise dose-response of the V? E/V?CO 2 slope in postmenopausal women in the DREW study
| dc.creator | Anaya, Stephanie A. | spa |
| dc.creator | Church, Timothy S. | spa |
| dc.creator | Blair, Steven N. | spa |
| dc.creator | Myers, Jonathan N. | spa |
| dc.creator | Earnest, Conrad P. | spa |
| dc.date.accessioned | 2020-08-19T14:43:25Z | |
| dc.date.available | 2020-08-19T14:43:25Z | |
| dc.date.created | 2009-05 | spa |
| dc.description.abstract | Purpose: Being overweight/obese, having hypertension, and being postmenopausal are risk factors for the development of congestive heart failure (CHF). A characteristic of CHF is an abnormal V?E/V?CO2 slope, which is predictive of mortality in patients with CHF. Although the V?E/V?CO2 slope is well established in CHF patients, little is known regarding interventions for 'at-risk' populations. Methods: We examined the V?E/V?CO2 slope in 401 sedentary, overweight, moderately hypertensive women randomized to 6 m of nonexercise (control) or 4 kcal·kg?1·wk?1 (KKW), 8 KKW, or 12 KKW of exercise at an intensity corresponding to 50% of baseline V?O2max. We examined trends in exercise treatment dose versus change in mean V?E/V?CO2 slope using a linear regression model (KKW vs V?E/V?CO2 slope) and a linear mixed model. Results: Regression analysis showed a significant trend for a reduction in the V?E/V?CO2 slope from baseline (mean ± SD: 32.6 ± 6.3; P < 0.004). When expressed as mean change (95% confidence interval (CI)) from baseline, we observed significant reductions in the V?E/V?CO2 slope for the 8-KKW (?1.14; 95% CI, ?1.5 to ?0.2) and 12-KKW (?1.67; 95% CI, ?2.3 to ?0.3) groups. No significant effect was noted for the 4-KKW (?0.4; 95% CI, ?1.2 to 0.15) group. Conclusion: Moderate-intensity aerobic exercise at doses of 8 KKW or greater seems to present an adequate dose of exercise to promote small but significant reductions in the V?E/V?CO2 slope in postmenopausal women who exhibit risk factors associated with the development of CHF. | eng |
| dc.format.mimetype | application/pdf | |
| dc.identifier.doi | https://doi.org/10.1249/MSS.0b013e3181930009 | |
| dc.identifier.issn | ISSN: 0195-9131 | |
| dc.identifier.issn | EISSN: 1530-0315 | |
| dc.identifier.uri | https://repository.urosario.edu.co/handle/10336/27702 | |
| dc.language.iso | eng | spa |
| dc.publisher | American College of Sports Medicine | spa |
| dc.relation.citationEndPage | 976 | |
| dc.relation.citationIssue | No. 5 | |
| dc.relation.citationStartPage | 971 | |
| dc.relation.citationTitle | Medicine and Science in Sports and Exercise | |
| dc.relation.citationVolume | Vol. 41 | |
| dc.relation.ispartof | Medicine and Science in Sports and Exercise, ISSN: 0195-9131;EISSN: 1530-0315, Vol.41, No.5 (May 2009); pp. 971-976 | spa |
| dc.relation.uri | https://www.cooperinstitute.org/vault/2440/web/files/640.pdf | spa |
| dc.rights.accesRights | info:eu-repo/semantics/openAccess | |
| dc.rights.acceso | Abierto (Texto Completo) | spa |
| dc.source | Medicine and Science in Sports and Exercise | spa |
| dc.source.instname | instname:Universidad del Rosario | |
| dc.source.reponame | reponame:Repositorio Institucional EdocUR | |
| dc.subject.keyword | Blood pressure | spa |
| dc.subject.keyword | Sedentary | spa |
| dc.subject.keyword | Ventilatory efficiency | spa |
| dc.subject.keyword | Cardiorespiratory fitness | spa |
| dc.title | Exercise dose-response of the V? E/V?CO 2 slope in postmenopausal women in the DREW study | spa |
| dc.title.TranslatedTitle | Ejercicio dosis-respuesta de la pendiente V? E / V?CO 2 en mujeres posmenopáusicas en el estudio DREW | spa |
| dc.type | article | eng |
| dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | |
| dc.type.spa | Artículo | spa |
