2026-04-26T23:30:46Zhttps://repository.urosario.edu.co/oai/request

oai:repository.urosario.edu.co:10336/190322019-09-19T07:37:54Zcom_10336_39998com_10336_563col_10336_683

Galindo-Mendez, Brahyan Mayor, Luis C. Velandia Hurtado, Fernando Alfredo Calderón Ospina, Carlos Alberto Galindo-Mendez, Brahyan Mayor, Luis C. Velandia-Hurtado, Fernando Calderon-Ospina, Carlos 2019-02-08T21:09:10Z 2019-02-08T21:09:10Z 2015 2015 Medically intractable epilepsy is a clinical condition of concern that arises when a patient with epilepsy suffers seizures, despite a trial of two or more antiepileptic drugs (AEDs) suitable for the type of epilepsy that are prescribed at maximum tolerated doses, does not achieve control of seizures. This diagnosis could be related to cortical dysplasias. We report the case of a 5-year-old girl with a previous normal neurological development and no family history of epilepsy who presented with focal-type seizures at age 4. She started treatment by taking different AEDs for seizure control. She continued having frequent seizures that sometimes progressed to generalized seizures and status epilepticus. After a focal cortical resection performed in the area where interictal spikes were detected, the pathology confirmed a type IIb cortical dysplasia as the cause of the epilepsy. This article discusses cortical dysplasias as a cause of pharmacoresistant epilepsy and its treatment. © 2015 The Authors. application/pdf ISSN 2213-3232 http://repository.urosario.edu.co/handle/10336/19032 eng 8 6 Epilepsy and Behavior Case Reports Vol. 4 Epilepsy and Behavior Case Reports, ISSN: 2213-3232, Vol. 4 (2015) pp. 6-8 https://ac.els-cdn.com/S2213323215000122/1-s2.0-S2213323215000122-main.pdf?_tid=49d8aeaf-6824-4c12-9de0-f79b4ba884c5&acdnat=1540056559_255e913a891300b3ccc0f5611b6541f6 info:eu-repo/semantics/openAccess Abierto (Texto Completo) https://creativecommons.org/licenses/by-nc-nd/4.0/ Wirrel, E.C., Predicting pharmacoresistance in pediatric epilepsy (2013) Epilepsia, 54, pp. 19-22 instname:Universidad del Rosario reponame:Repositorio Institucional EdocUR Anticonvulsants Cortical Dysplasia-Focal Epilepsy Syndrome Drug Resistance Epilepsy Malformations Of Cortical Development Enfermedades Anticonvulsive Agent Carbamazepine Clonazepam Etiracetam Gabapentin Harkoseride Lamotrigine Midazolam Oxcarbazepine Phenobarbital Primidone Topiramate Article Ataxia Brain Cortex Lesion Brain Surgery Case Report Child Cortical Dysplasia Disease Control Disease Course Drug Eruption Drug Treatment Failure Epileptic State Family History Female Focal Epilepsy Human Intractable Epilepsy Nervous System Development Onset Age Preschool Child Priority Journal Seizure Tonic Clonic Seizure Epilepsia Convulsiones Niños epilépticos Failure of antiepileptic drugs in controlling seizures in epilepsy : What do we do next? article info:eu-repo/semantics/publishedVersion Artículo