Ítem
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The nature and nurture of common autoimmunity
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Autores
CASTIBLANCO, JOHN
Anaya, Juan-Manuel
Fecha
2007
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Editor
Blackwell Publishing Inc.
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Resumen
Abstract
Autoimmune diseases are a heterogeneous group of disorders where multiple alterations in the immune system result in a spectrum of syndromes that either target specific organs or affect the body systematically. Although their heterogeneity is due to a collection of diverse conditions based on epidemiology, pathology, or diagnostic criteria, the underlying immunogenetic mechanism might be similar. Herein the nature and nurture of autoimmune diseases considered as a trait are reviewed, and a discussion is given on their multifactorial characteristics. © 2007 New York Academy of Sciences.
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Keywords
Autoimmune disease , Autoimmunity , Conference paper , Genetic linkage , Heredity , Human , Immune system , Immunogenetics , Immunopathogenesis , Phenotype , Animal , Article , Autoimmune disease , Autoimmunity , Biological model , Disease predisposition , Genetics , Immunology , Pathology , Animals , Autoimmune diseases , Autoimmunity , Disease susceptibility , Humans , Models , Aggregation , Autoimmune disease , Inheritance patterns , Linkage , Segregation
