Ítem
Solo Metadatos
Pulmonary involvement in systemic sclerosis
Título de la revista
Autores
Morales-Cárdenas, Adriana
Pérez-Madrid, Camila
Arias, Liliana
Ojeda, Paulina
Mahecha, María Paula
Rojas-Villarraga, Adriana
Carrillo-Bayona, Jorge A.
Anaya, Juan-Manuel
Fecha
2016
Directores
ISSN de la revista
Título del volumen
Editor
Elsevier B.V.
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Resumen
Abstract
Systemic sclerosis (SSc) is a multi-systemic autoimmune disease that mainly affects the skin, lungs, gastrointestinal tract, heart and kidneys. Pulmonary disease in patients with SSc is strongly associated with mortality. The mechanisms involved into its pathophysiology include the activation of autoimmune cells and hyperplasia of fibroblasts with an increased capacity to produce collagen and diminished collagen breakdown. Although pulmonary biopsy is the gold standard for the diagnosis of interstitial lung disease in SSc, the most commonly used method is high-resolution computed tomography due to its high sensitivity and specificity. Herein, a comprehensive review on the pulmonary involvement in SSc is presented highlighting the radiologic–pathologic correlations. © 2016 Elsevier B.V.
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Keywords
Biological marker , interstitial , x-ray computed , interstitial , systemic , Aspiration bronchiolitis , Aspiration pneumonia , Bronchiolitis , Bronchiolocentric fibrosis , Clinical feature , Combined pulmonary fibrosis and emphysema , Diaphragm disease , Diffuse alveolar damage , Epidemiology , Histopathology , Human , Interstitial pneumonia , Lung cancer , Lung disease , Lung emphysema , Lung fibrosis , Lung hemorrhage , Lung infection , Non specific interstitial pneumonia , Organizing pneumonia , Pathophysiology , Pulmonary capillary hemangiomatosis , Pulmonary hypertension , Pulmonary veno-occlusive disease , Review , Systematic review , Systemic sclerosis , Thorax radiography , Usual interstitial pneumonia , Complication , Diagnostic imaging , Female , Immunology , Lung , Lung diseases , Male , Pathology , Systemic sclerosis , X-ray computed tomography , Female , Humans , Lung , Lung diseases , Male , Scleroderma , Tomography , Pathology , Pulmonary involvement , Radiology , Systemic sclerosis , Tomography , X-ray computed
