Ítem
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Personalized medicine. Closing the gap between knowledge and clinical practice
Título de la revista
Autores
Anaya, Juan-Manuel
Duarte-Rey, Carolina
Sarmiento-Monroy, Juan C.
Bardey, David
Castiblanco, John
Rojas-Villarraga, Adriana
Fecha
2016
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Editor
Elsevier B.V.
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Resumen
Abstract
Personalized medicine encompasses a broad and evolving field informed by a patient distinctive information and biomarker profile. Although terminology is evolving and some semantic interpretations exist (e.g., personalized, individualized, precision), in a broad sense personalized medicine can be coined as: “To practice medicine as it once used to be in the past using the current biotechnological tools.” A humanized approach to personalized medicine would offer the possibility of exploiting systems biology and its concept of P5 medicine, where predictive factors for developing a disease should be examined within populations in order to establish preventive measures on at-risk individuals, for whom healthcare should be personalized and participatory. Herein, the process of personalized medicine is presented together with the options that can be offered in health care systems with limited resources for diseases like rheumatoid arthritis and type 1 diabetes. © 2016 Elsevier B.V.
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Keywords
Autoimmune disease , Clinical practice , human , Developing country , Human , Insulin dependent diabetes mellitus , Personalized medicine , Review , Rheumatoid arthritis , Systematic review (topic) , Autoimmune diseases , Health care delivery , Human genome , Personalized medicine , Preventive medicine , Procedures , Biological marker , Autoimmune diseases , Biomarkers , Delivery of health care , Developing countries , Genome , Humans , Precision medicine , Preventive medicine , Autoimmune ecology , Developing countries , Pharmacogenomics , Precision medicine , Rheumatoid arthritis , Type 1 diabetes
