Ítem
Acceso Abierto
Refractory Immunological Thrombocytopenia Purpura and Splenectomy in Pregnancy
Título de la revista
Autores
Bernal-Macías, Santiago
Fino-Velásquez, Laura-Marcela
Vargas-Barato, Felipe E
Guerra-Galue, Lucio
Reyes-Beltran, Benjamin
Rojas-Villarraga, Adriana
Archivos
Fecha
2015
Directores
ISSN de la revista
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Editor
Case Reports in Immunology
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Resumen
Abstract
Thrombocytopenia is defined as a platelet count of less than 100,000 platelets per microlitre (mcL). Thrombocytopenia develops in approximately 6-7% of women during pregnancy and at least 3% of these cases are caused by immunological platelet destruction. Herein, we present a pregnant woman who develops at the first trimester autoimmune thrombocytopenia purpura associated with positive antiphospholipid antibodies. The disease was refractory to pharmacological treatments but had a favourable response to splenectomy. The patient carried the pregnancy to term without complication and gave birth to a healthy baby girl.
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Keywords
Thrombocytopenia , Pregnancy , Immunological platelet destruction , Pharmacological treatments