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Autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA) after quadrivalent human papillomavirus vaccination in Colombians: a call for personalised medicine

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Autores
Anaya, Juan-Manuel
Reyes-Beltran, Benjamin
Perdomo-Arciniegas, Ana M
Camacho-Rodríguez, Bernardo
Rojas-Villarraga, Adriana

Fecha
2015-07-20

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Editor
Clinical and Experimental Rheumatology

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Abstract
This was a case study in which 3 patients with autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA) after quadrivalent human papillomavirus vaccination (HPV) were evaluated and described. All the patients were women. Diagnosis consisted of HLA-B27 enthesitis related arthritis, rheumatoid arthritis and systemic lupus erythematous, respectively. Our results highlight the risk of developing ASIA after HPV vaccination and may serve to increase the awareness of such a complication. Factors that are predictive of developing autoimmune diseases should be examined at the population level in order to establish preventive measures in at-risk individuals for whom healthcare should be personalised and participatory.
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Keywords
ASIA human , Papillomavirus vaccine , Autoimmune disease , Spondyloarthritis , HLA
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