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Measuring Near-Infrared Spectroscopy Derived Cerebral Autoregulation in Neonates: From Research Tool Toward Bedside Multimodal Monitoring

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Caicedo Dorado, Alexande
Thewissen, Liesbeth
Naulaers, G
Van Huffel, S
Lemmers, Petra
Van Bel, Frank

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2018-04-14

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Frontiers Media S.A

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Abstract
Cerebral autoregulation (CAR), the ability of the human body to maintain cerebral blood flow (CBF) in a wide range of perfusion pressures, can be calculated by describing the relation between arterial blood pressure (ABP) and cerebral oxygen saturation measured by near-infrared spectroscopy (NIRS). In literature, disturbed CAR is described in different patient groups, using multiple measurement techniques and mathematical models. Furthermore, it is unclear to what extent cerebral pathology and outcome can be explained by impaired CAR.
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Cerebral autoregulation , NEAR-infrared spectroscopy (NIRS) , Neonate , Cerebral blood flow (CBF) , Arterial blood pressure , Outcome , Multimodal monitoring , Mathematical model
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