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Hallazgos radiológicos de la enfermedad pulmonar en pacientes Colombianos con esclerodermia

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dc.contributor.advisorAnaya, Juan-Manuel
dc.contributor.advisorMolano González,Nicolás
dc.creatorMorales, Adriana
dc.creatorPérez, Camila
dc.creatorMolano González, Nicolás
dc.creatorRojas-Villarraga, Adriana
dc.creatorCarrillo Bayona, Jorge Alberto
dc.creatorAnaya, Juan-Manuel
dc.creator.degreeEspecialista en Epidemiología (en Convenio con el CES)
dc.date.accessioned2015-11-13T20:50:29Z
dc.date.available2015-11-13T20:50:29Z
dc.date.created2015-06-26
dc.date.issued2015
dc.descriptionLa esclerosis sistémica (ES) es una enfermedad autoinmune multisistémica que afecta principalmente la piel, los pulmones, el tracto gastrointestinal, el corazón y los riñones. La enfermedad pulmonar, presente en casi el 100% de los casos, es el factor con mayor influencia en la mortalidad. El propósito de este estudio es realizar un análisis detallado de la enfermedad pulmonar por tomografía computarizada de alta resolución(TCAR) en pacientes Colombianos con ES, para lo cual se realizó un estudio de prevalencia analítica en 44 pacientes con ES valorados en el Hospital Universitario Mayor Méderi en los últimos 7 años. Los resultados mostraron características demográficas y clínicas similares a las previamente descritas. La prevalencia de enfermedad pulmonar intersticial fue alta, y los hallazgos de fibrosis pulmonar como vidrio esmerilado y panal de abejas se asociaron con la presencia del autoanticuerpo antiSCL70. La medida del diámetro esofágico por TCAR fue mayor en los pacientes con disfagia, antiSCL 70 y linfopenia, los cuales son marcadores de mal pronóstico.spa
dc.description.abstractSystemic sclerosis (SSc) is a multisystem autoimmune disease that primarily affects the skin, lungs, gastrointestinal tract, heart and kidneys. Lung disease, present in almost 100% of cases, is the most influential factor in mortality. The purpose of this study is to perform a detailed analysis of lung disease CT high resolution in Colombian patients with SSc, for which a study of analytical prevalence was performed in 44 patients with ES valued at University Hospital Mayor mederi in the last 7 years. The results showed demographic characteristics similar to those previously described clinics. The prevalence of interstitial lung disease was high, and the findings of pulmonary fibrosis as "ground glass" and "honeycomb" were associated with the presence of autoantibody antiSCL70. The measure HRCT esophageal diameter was greater in patients with dysphagia, antiSCL 70 and lymphopenia, which are markers of poor prognosis.eng
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dc.identifier.doihttps://doi.org/10.48713/10336_11507
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/11507
dc.language.isospa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentFacultad de medicinaspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto completo)spa
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dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectEsclerodermiaspa
dc.subjectenfermedad pulmonarspa
dc.subjectfibrosis pulmonarspa
dc.subjecthipertensión pulmonarspa
dc.subjectesofagopatíaspa
dc.subject.ddcEnfermedades
dc.subject.decsEnfermedades Pulmonaresspa
dc.subject.decsFibrosis Pulmonarspa
dc.subject.decsEsclerodermia Sistémicaspa
dc.subject.keywordSystemic sclerosiseng
dc.subject.keywordpulmonary diseaseeng
dc.subject.keywordpulmonary fibrosiseng
dc.subject.keywordpulmonary hypertensioneng
dc.subject.keywordesophagopathyeng
dc.subject.lembEpidemiologíaspa
dc.subject.lembEnfermedades de los pulmonesspa
dc.titleHallazgos radiológicos de la enfermedad pulmonar en pacientes Colombianos con esclerodermiaspa
dc.title.TranslatedTitleRadiologic findings of pulmonary involvement in Colombian patients with systemic sclerosiseng
dc.typebachelorThesiseng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTrabajo de gradospa
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Especialización en Epidemiología