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Are autoimmune diseases predictable?

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dc.creatorTobón, Gabriel J.spa
dc.creatorPers, Jacques-Olivierspa
dc.creatorCañas, Carlos A.spa
dc.creatorRojas-Villarraga, Adrianaspa
dc.creatorYouinou, Pierrespa
dc.creatorAnaya, Juan-Manuelspa
dc.date.accessioned2020-05-25T23:59:56Z
dc.date.available2020-05-25T23:59:56Z
dc.date.created2012spa
dc.description.abstractAutoimmune diseases are complex diseases resulting of the interaction between both genetics and environmental factors over time. Different phases in the development of autoimmune diseases are characterized by the detection of serum autoantibodies several months or years before the onset of clinical manifestations and subsequent diagnosis. In addition to serum antibodies, genetic susceptibility factors may predict the future development of the disease. Currently, prediction in type 1 diabetes is the most accurate, with the analysis of genetic susceptibility factors in first-degree relatives of patients and several autoantibody tests. In the future, multiple antibodies test, in combination with the analysis of genetics, epigenetics and immunological anomalies in fine models may allow the precise prediction in autoimmune diseases. Prevention measures might thus be introduced as an attempt to avoid or delay the disease. © 2011 Elsevier B.V.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.autrev.2011.10.004
dc.identifier.issn15689972
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23133
dc.language.isoengspa
dc.relation.citationEndPage266
dc.relation.citationIssueNo. 4
dc.relation.citationStartPage259
dc.relation.citationTitleAutoimmunity Reviews
dc.relation.citationVolumeVol. 11
dc.relation.ispartofAutoimmunity Reviews, ISSN:15689972, Vol.11, No.4 (2012); pp. 259-266spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84857055126&doi=10.1016%2fj.autrev.2011.10.004&partnerID=40&md5=7b7b793910f5797e7ae59e2376218682spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAntinuclear antibodyspa
dc.subject.keywordAutoantibodyspa
dc.subject.keywordanimaleng
dc.subject.keywordGlutamate decarboxylasespa
dc.subject.keywordImmunosuppressive agentspa
dc.subject.keywordPhospholipid antibodyspa
dc.subject.keywordAcquired immune deficiency syndromespa
dc.subject.keywordAllelespa
dc.subject.keywordAntibody detectionspa
dc.subject.keywordAutoimmune diseasespa
dc.subject.keywordClinical trialspa
dc.subject.keywordGenetic susceptibilityspa
dc.subject.keywordGeneticsspa
dc.subject.keywordHumanspa
dc.subject.keywordInsulin dependent diabetes mellitusspa
dc.subject.keywordReviewspa
dc.subject.keywordRheumatoid arthritisspa
dc.subject.keywordSystemic lupus erythematosusspa
dc.subject.keywordAnimalsspa
dc.subject.keywordAutoantibodiesspa
dc.subject.keywordAutoimmune diseasesspa
dc.subject.keywordDisease modelseng
dc.subject.keywordGene-environment interactionspa
dc.subject.keywordGenetic predisposition to diseasespa
dc.subject.keywordGenetic testingspa
dc.subject.keywordHumansspa
dc.subject.keywordPrognosisspa
dc.subject.keywordSerologyspa
dc.subject.keywordAuto-antibodiesspa
dc.subject.keywordAutoimmune diseasesspa
dc.subject.keywordGenetic susceptibilityspa
dc.subject.keywordPositive predictive valuespa
dc.subject.keywordPredictionspa
dc.titleAre autoimmune diseases predictable?spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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