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Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria

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dc.creatorCubillos, Marciaspa
dc.creatorAlba, Martha Patriciaspa
dc.creatorBermudez, Adriana
dc.creatorTrujillo, Maryspa
dc.creatorPatarroyo, Manuel Elkinspa
dc.date.accessioned2020-08-19T14:40:09Z
dc.date.available2020-08-19T14:40:09Z
dc.date.created2003-07spa
dc.description.abstractThree Plasmodium falciparum serine repeat antigen (SERA) protein peptides were studied by NMR and structure calculations being done in 70:30 water:trifluoroethanol solution. Peptide 22834 was shown to be immunogenic and protective against malaria in Aotus monkeys, whilst native peptide 6737 and its analogue 14096 did not present protection against the disease in these monkeys. Results showed a relationship between these peptides’ secondary structure and their function as immunogen against malaria.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/S0300-9084(03)00136-6
dc.identifier.issnISSN: 0300-9084
dc.identifier.issnEISSN: 1638-6183
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/26739
dc.language.isoengspa
dc.publisherSociété Française de Biochimie et Biologie Moléculaire (SFBBM)spa
dc.publisherElsevierspa
dc.relation.citationEndPage657
dc.relation.citationIssueNo. 7
dc.relation.citationStartPage651
dc.relation.citationTitleBiochimie
dc.relation.citationVolumeVol. 85
dc.relation.ispartofBiochimie, ISSN: 0300-9084;EISSN: 1638-6183, Vol.85, No.7 (2003); pp. 651-657 spa
dc.relation.urihttps://www.sciencedirect.com/science/article/abs/pii/S0300908403001366spa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceBiochimiespa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordMalariaspa
dc.subject.keywordPeptidesspa
dc.subject.keywordSERA proteinspa
dc.subject.keywordStructurespa
dc.subject.keywordVaccinespa
dc.titlePlasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malariaspa
dc.title.TranslatedTitleLos análogos de péptidos de la proteína SERA de Plasmodium falciparum que tienen regiones helicoidales cortas inducen protección contra la malariaspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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