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Factores de riesgo para transfusión intraoperatoria de globulos rojos en trasplante hepático en la Fundación Cardioinfatil

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dc.contributorMejia, Gilberto
dc.contributorRivera, Jairo
dc.contributor.advisorFranco Gruntorad, Germán Andrés
dc.contributor.advisorAlzate, Juan Pablo
dc.creatorBallen Tole, Manuel Camilo
dc.creator.degreeEspecialista en Anestesiología FCIspa
dc.date.accessioned2018-08-17T20:28:31Z
dc.date.available2018-08-17T20:28:31Z
dc.date.created2018-07-26
dc.date.issued2018
dc.descriptionIntroducción: El trasplante hepático es un procedimiento salvador en pacientes con patología hepática terminal. La hemorragia que requiere transfusión de glóbulos rojos empaquetados (GRE) es una de las complicaciones más frecuentes y se asocia con un aumento de la morbimortalidad. Objetivo: Identificar factores de riesgo asociados a la transfusión de GRE durante el intraoperatorio en los pacientes adultos sometidos a trasplante hepático en la Fundación CardioInfantil. Métodos: Estudio analítico de casos y controles, se dividió la población de pacientes que fueron llevados al procedimiento en aquellos que requirieron transfusión de GRE y aquellos que no, se analizaron factores de riesgo identificados y conductas que podrían disminuir la probabilidad de transfusión de GRE. La población de referencia fueron los pacientes en quienes se realizó trasplante hepático ortotópico durante 2013-2017. Resultados: Se identificaron 190 procedimientos, la frecuencia de transfusión de GRE fue de 54,2%, posterior al análisis multivariado contrario a lo que había sido concluido por otros investigadores el uso de salvador de células se comportó como factor de riesgo; coincidiendo con lo reportado por otros grupos de trasplante hepático el tiempo de fase anhepática superior a 50 minutos, edad del donante mayor a 39,5 años y como factor protector hemoglobina (Hb) mayor a 12,6 g/dl siendo este último parámetro el que puede ser optimizado previo al procedimiento. Discusión: Se considera que para optimizar la morbimortalidad de los pacientes que van a ser llevados a este procedimiento se debe optimizar la Hb mientras el paciente se encuentre en lista de espera.spa
dc.description.abstractIntroduction: Liver transplant is a salvage procedure in patients with terminal liver pathology. Hemorrhage with requirement of red blood cell (RBC) transfusion is a common complication associated with increased morbidity and mortality. Objective: To Recognize risk factors associated with intraoperative use of RBC transfusion in adult patients undergoing liver transplantation at CardioInfantil Foundation Center. Method: Sample population consists of patients who required orthotopic liver transplant between 2013-2017. A case control study was performed. the group of patients undergoing the procedure was divided between patients who required RBC transfusion and those who did not require RBC transfusion, risk factors and strategies that could decrease RBC transfusion were analyzed. Results: 190 procedures were included, RBC transfusion requirement frequency was 54,2%; after multivariate analysis and contrary to previous publications, use of cell saver was a risk factor RBC transfusion. Like results reported by other liver transplant groups anhepatic phase more than 50 minutes, donor age more than 39,5 years old and hemoglobin (hb) greater than 12,6 g/dl were protector variables for RBC transfusion. Discussion: To optimize morbidity and mortality of patients undergoing liver transplantation, hb must be optimized.spa
dc.description.embargo2019-08-18 01:01:01: Script de automatizacion de embargos. info:eu-repo/date/embargoEnd/2019-08-17spa
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dc.identifier.doihttps://doi.org/10.48713/10336_18312
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/18312
dc.language.isospa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentFacultad de Medicinaspa
dc.publisher.programEspecialización en Anestesiología FCIspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
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dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectTrasplante hepáticospa
dc.subjectTransfusiónspa
dc.subjectGlóbulos rojosspa
dc.subjectGlóbulos rojos empaquetadosspa
dc.subjectFactores de riesgospa
dc.subjectSalvador de células hemoglobinaspa
dc.subject.ddcVarias ramas de la medicina, Cirugía spa
dc.subject.keywordTranfusionspa
dc.subject.keywordLiver transplantspa
dc.subject.keywordRed blood cellsspa
dc.subject.keywordRisk factorsspa
dc.subject.keywordCell saverspa
dc.subject.keywordHemoglobinspa
dc.subject.lembTrasplantes de hígadospa
dc.subject.lembEritrocitosspa
dc.titleFactores de riesgo para transfusión intraoperatoria de globulos rojos en trasplante hepático en la Fundación Cardioinfatilspa
dc.typemasterThesiseng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTrabajo de gradospa
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