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Cerebral tissue oxygenation and regional oxygen saturation can be used to study cerebral autoregulation in prematurely born infants

dc.creatorCaicedo Dorado, Alexander
dc.creatorDe Smet, Dominiquespa
dc.creatorNaulaers, Gunnarspa
dc.creatorAmeye, Lievekespa
dc.creatorVanderhaegen, Jokespa
dc.creatorLemmers, Petraspa
dc.creatorvan Bel, Frankspa
dc.creatorVan Huffel, Sabinespa
dc.date.accessioned2020-08-19T14:41:51Z
dc.date.available2020-08-19T14:41:51Z
dc.date.created2011-06spa
dc.description.abstractThe coupling of cerebral intravascular oxygenation (dHbD) with mean arterial blood pressure (MABP) was taken as a reflection of autoregulation assuming constant arterial oxygen content. However, this method is sensitive to movement artifacts. We examined whether the cerebral tissue oxygenation index (cTOI) and regional oxygen saturation (rScO2) may replace dHbD and changes in total Hb (dHbT), respectively. Correlation (COR) and coherence (COH) were used to measure the agreement of MABP with rScO2/dHbT and cTOI/dHbD. dHbD/cTOI and dHbT/rScO2 recordings of, respectively, 34 and 20 preterm infants in need for intensive care were studied during the first days of life. dHbD and cTOI were obtained with the NIRO300 and rScO2 and dHbT with the INVOS4100. Invasive MABP was measured continuously. COR and COH scores of MABP versus dHbD/dHbT were compared with the corresponding ones by replacing dHbD/dHbT by cTOI/rScO2, respectively. Generally, no significant score differences were found for dHbD/cTOI. Differences for dHbT/rScO2 were slightly larger but still within the normal variation of the parameters. Differences become insignificant when restricting calculations to epochs of larger variation in MABP (>10 mm Hg). Hence, we suggest that cTOI and rScO2 can be used to study cerebral autoregulation in newborns.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1203/PDR.0b013e3182176d85
dc.identifier.issnISSN: 0031-3998
dc.identifier.issnEISSN: 1530-0447
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/27350
dc.language.isoengspa
dc.publisherInternational Pediatric Research Foundationspa
dc.publisherSpringer Naturespa
dc.relation.citationEndPage553
dc.relation.citationIssueNo. 6
dc.relation.citationStartPage548
dc.relation.citationTitlePediatric Research
dc.relation.citationVolumeVol. 69
dc.relation.ispartofPediatric Research, ISSN: 0031-3998;EISSN: 1530-0447, Vol 69, No.6 (2011); pp. 548-553spa
dc.relation.urihttps://www.nature.com/articles/pr2011115.pdfspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.sourcePediatric Researchspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordPaediatricsspa
dc.subject.keywordPhysiologyspa
dc.titleCerebral tissue oxygenation and regional oxygen saturation can be used to study cerebral autoregulation in prematurely born infantsspa
dc.title.TranslatedTitleLa oxigenación del tejido cerebral y la saturación regional de oxígeno se pueden utilizar para estudiar la autorregulación cerebral en bebés prematuros.spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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