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Intrinsic properties and functional changes in spastic muscle after application of BTX-A in children with cerebral palsy: systematic review

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dc.creatorGarcía Salazar, Luisa Fernanda
dc.creatorLopes dos Santos, Gabrielaspa
dc.creatorPavao, Silvia Letíciaspa
dc.creatorCicuto Ferreira Rocha, Nelci Adrianaspa
dc.creatorde Russo, Thiago Luizspa
dc.date.accessioned2020-08-28T15:48:13Z
dc.date.available2020-08-28T15:48:13Z
dc.date.created2014-09-02spa
dc.description.abstractObjective: This article aimed to review the literature to verify the effect of botulinum toxin type A (BTX-A) on the intrinsic properties of spastic muscles and functionality in children with cerebral palsy (CP). Methods: A literature search was conducted in the following databases: CINAHL, SCOPUS, Web of Science and PubMed. Database searches were limited to the period from January 1993 to March 2014. Results: A total of 2182 papers were identified, and 17 met the inclusion criteria. Only one study analyzed the effect of the toxin on muscle intrinsic properties and others analyzed the effect on functionality. Conclusion: BTX-A application demonstrated no changes in the passive stiffness of spastic muscle. In relation to functional level, the evidence of BTX-A effect was controversial. These studies showed methodological quality limitations that restrict the interpretation of the results for the entire CP population, which justifies the need for further randomized controlled trials.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.3109/17518423.2014.948640
dc.identifier.issnISSN: 1751-8423
dc.identifier.issnEISSN: 1751-8431
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/28451
dc.language.isoengspa
dc.publisherTaylor & Francisspa
dc.relation.citationEndPage14
dc.relation.citationIssueNo. 1
dc.relation.citationStartPage1
dc.relation.citationTitleDevelopmental Neurorehabilitation
dc.relation.citationVolumeVol. 18
dc.relation.ispartofDevelopmental Neurorehabilitation, ISSN: 1751-8423;EISSN: 1751-8431, Vol. 18, No. 1 (2015); pp. 1-14spa
dc.relation.urihttps://www.tandfonline.com/doi/abs/10.3109/17518423.2014.948640spa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceDevelopmental Neurorehabilitationspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordBotulinum toxinspa
dc.subject.keywordFunctionalityspa
dc.subject.keywordMotor developmentalspa
dc.subject.keywordMuscle spasticityspa
dc.subject.keywordRehabilitationspa
dc.titleIntrinsic properties and functional changes in spastic muscle after application of BTX-A in children with cerebral palsy: systematic reviewspa
dc.title.TranslatedTitlePropiedades intrínsecas y cambios funcionales en el músculo espástico después de la aplicación de BTX-A en niños con parálisis cerebral: revisión sistemáticaspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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